The dual PI3K/mTOR inhibitor NVP‐BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial‐lysosomal cross‐talk
Seitz, Christian, Hugle, Manuela, Cristofanon, Silvia, Tchoghandjian, Aurélie, Fulda, Simone
Published in International journal of cancer (01.06.2013)
Published in International journal of cancer (01.06.2013)
Get full text
Journal Article
Smac Mimetic Bypasses Apoptosis Resistance in FADD- or Caspase-8-Deficient Cells by Priming for Tumor Necrosis Factor α-Induced Necroptosis
Laukens, Bram, Jennewein, Claudia, Schenk, Barbara, Vanlangenakker, Nele, Schier, Alexander, Cristofanon, Silvia, Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu J.M, Vandenabeele, Peter, Fulda, Simone
Published in Neoplasia (New York, N.Y.) (01.10.2011)
Published in Neoplasia (New York, N.Y.) (01.10.2011)
Get full text
Journal Article
Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network
Signaroldi, Elena, Laise, Pasquale, Cristofanon, Silvia, Brancaccio, Arianna, Reisoli, Elisa, Atashpaz, Sina, Terreni, Maria Rosa, Doglioni, Claudio, Pruneri, Giancarlo, Malatesta, Paolo, Testa, Giuseppe
Published in Nature communications (29.02.2016)
Published in Nature communications (29.02.2016)
Get full text
Journal Article
Requirement of Nuclear Factor κB for Smac Mimetic–Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis
Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Published in Neoplasia (New York, N.Y.) (01.12.2011)
Published in Neoplasia (New York, N.Y.) (01.12.2011)
Get full text
Journal Article
Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275
Bangert, Annette, Häcker, Sabine, Cristofanon, Silvia, Debatin, Klaus-Michael, Fulda, Simone
Published in Anti-cancer drugs (01.07.2011)
Published in Anti-cancer drugs (01.07.2011)
Get more information
Journal Article
Subapoptogenic Oxidative Stress Strongly Increases the Activity of the Glycolytic Key Enzyme Glyceraldehyde 3-Phosphate Dehydrogenase
Cerella, Claudia, D'Alessio, Maria, Cristofanon, Silvia, De Nicola, Milena, Radogna, Flavia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina
Published in Annals of the New York Academy of Sciences (01.08.2009)
Published in Annals of the New York Academy of Sciences (01.08.2009)
Get full text
Journal Article
Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis
UNTERKIRCHER, Thomas, CRISTOFANON, Silvia, KRISHNA VELLANKI, Sri Hari, NONNENMACHER, Lisa, KARPEL-MASSLER, Georg, WIRTZ, Christian Rainer, DEBATIN, Klaus-Michael, FULDA, Simone
Published in Clinical cancer research (15.06.2011)
Published in Clinical cancer research (15.06.2011)
Get full text
Journal Article
Intracellular Prooxidant Activity of Melatonin Induces a Survival Pathway Involving NF-κB Activation
Cristofanon, Silvia, Uguccioni, Francesco, Cerella, Claudia, Radogna, Flavia, Dicato, Mario, Ghibelli, Lina, Diederich, Marc
Published in Annals of the New York Academy of Sciences (01.08.2009)
Published in Annals of the New York Academy of Sciences (01.08.2009)
Get full text
Journal Article
Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2
Radogna, Flavia, Cristofanon, Silvia, Paternoster, Laura, D'Alessio, Maria, De Nicola, Milena, Cerella, Claudia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina
Published in Journal of pineal research (01.04.2008)
Published in Journal of pineal research (01.04.2008)
Get full text
Journal Article
NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis
Berger, Rebecca, Jennewein, Claudia, Marschall, Viola, Karl, Sabine, Cristofanon, Silvia, Wagner, Liane, Vellanki, Sri HariKrishna, Hehlgans, Stephanie, Rödel, Franz, Debatin, Klaus-Michael, Ludolph, Albert C, Fulda, Simone
Published in Molecular cancer therapeutics (01.10.2011)
Published in Molecular cancer therapeutics (01.10.2011)
Get full text
Journal Article
Tumor necrosis factor α inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation
Buck, Isabelle, Morceau, Franck, Cristofanon, Silvia, Heintz, Caroline, Chateauvieux, Sébastien, Reuter, Simone, Dicato, Mario, Diederich, Marc
Published in Biochemical pharmacology (15.11.2008)
Published in Biochemical pharmacology (15.11.2008)
Get full text
Journal Article
Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4)
Cerella, Claudia, Scherer, Christiane, Cristofanon, Silvia, Henry, Estelle, Anwar, Awais, Busch, Corinna, Montenarh, Mathias, Dicato, Mario, Jacob, Claus, Diederich, Marc
Published in Apoptosis (London) (01.05.2009)
Published in Apoptosis (London) (01.05.2009)
Get full text
Journal Article
The inhibition of TNF-α-induced NF-κB activation by marine natural products
Folmer, Florence, Jaspars, Marcel, Solano, Godofredo, Cristofanon, Silvia, Henry, Estelle, Tabudravu, Jioji, Black, Kenny, Green, David H., Küpper, Frithjof C., Aalbersberg, William, Feussner, Klaus, Dicato, Mario, Diederich, Marc
Published in Biochemical pharmacology (15.09.2009)
Published in Biochemical pharmacology (15.09.2009)
Get full text
Journal Article
Abstract 2278: Smac mimetic primes FADD- or caspase-8-deficient leukemia cells for TNFα-induced necroptosis and overcomes apoptosis resistance
Schenk, Barbara, Laukens, Bram, Jennewein, Claudia, Vanlangenakker, Nele, Cristofanon, Silvia, Vucic, Domagoj, Jeremias, Irmela, Bertrand, Mathieu, Vandenabeele, Peter, Fulda, Simone
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Get full text
Journal Article
Tumor necrosis factor α induces γ-glutamyltransferase expression via nuclear factor-κB in cooperation with Sp1
Reuter, Simone, Schnekenburger, Michael, Cristofanon, Silvia, Buck, Isabelle, Teiten, Marie-Hélène, Daubeuf, Sandrine, Eifes, Serge, Dicato, Mario, Aggarwal, Bharat B., Visvikis, Athanase, Diederich, Marc
Published in Biochemical pharmacology (01.02.2009)
Published in Biochemical pharmacology (01.02.2009)
Get full text
Journal Article
Requirement of Nuclear Factor κB for Smac Mimetic-Mediated Sensitization of Pancreatic Carcinoma Cells for Gemcitabine-Induced Apoptosis12
Stadel, Dominic, Cristofanon, Silvia, Abhari, Behnaz Ahangarian, Deshayes, Kurt, Zobel, Kerry, Vucic, Domagoj, Debatin, Klaus-Michael, Fulda, Simone
Published in Neoplasia (New York, N.Y.) (01.12.2011)
Get full text
Published in Neoplasia (New York, N.Y.) (01.12.2011)
Journal Article
Subapoptogenic Oxidative Stress Strongly Increases the Activity of the Glycolytic Key Enzyme Glyceraldehyde 3‐Phosphate Dehydrogenase: Possible Involvement in an Adaptative Response to the Stress
Cerella, Claudia, D’Alessio, Maria, Cristofanon, Silvia, De Nicola, Milena, Radogna, Flavia, Dicato, Mario, Diederich, Marc, Ghibelli, Lina
Published in Annals of the New York Academy of Sciences (01.01.2009)
Published in Annals of the New York Academy of Sciences (01.01.2009)
Get full text
Journal Article
Intracellular Prooxidant Activity of Melatonin Induces a Survival Pathway Involving NF-KB Activation
Cristofanon, Silvia, Uguccioni, Francesco, Cerella, Claudia, Radogna, Flavia, Dicato, Mario, Ghibelli, Lina, Diederich, Marc
Published in Annals of the New York Academy of Sciences (01.08.2009)
Published in Annals of the New York Academy of Sciences (01.08.2009)
Get full text
Journal Article