Asymptomatic hyperuricaemia: a silent activator of the innate immune system
Joosten, Leo A. B., Crişan, Tania O., Bjornstad, Petter, Johnson, Richard J.
Published in Nature reviews. Rheumatology (01.02.2020)
Published in Nature reviews. Rheumatology (01.02.2020)
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Journal Article
Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia
Cabău, Georgiana, Crișan, Tania O., Klück, Viola, Popp, Radu A., Joosten, Leo A. B.
Published in Immunological reviews (01.03.2020)
Published in Immunological reviews (01.03.2020)
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Journal Article
Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway
Crişan, Tania O., Cleophas, Maartje C. P., Novakovic, Boris, Erler, Kathrin, van de Veerdonk, Frank L., Stunnenberg, Hendrik G., Netea, Mihai G., Dinarello, Charles A., Joosten, Leo A. B.
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2017)
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Journal Article
GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells
Gaal, Orsolya I., Liu, Ruiqi, Marginean, Dragoș, Badii, Medeea, Cabău, Georgiana, Hotea, Ioana, Nica, Valentin, Colcear, Doina, Pamfil, Cristina, Merriman, Tony R., Rednic, Simona, Popp, Radu A., Crișan, Tania O., Joosten, Leo A. B.
Published in Scientific reports (12.02.2024)
Published in Scientific reports (12.02.2024)
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Journal Article
Innate immune memory: Implications for host responses to damage‐associated molecular patterns
Crișan, Tania O., Netea, Mihai G., Joosten, Leo A. B.
Published in European journal of immunology (01.04.2016)
Published in European journal of immunology (01.04.2016)
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Journal Article
Inflammasome-independent modulation of cytokine response by autophagy in human cells
Crişan, Tania O, Plantinga, Theo S, van de Veerdonk, Frank L, Farcaş, Marius F, Stoffels, Monique, Kullberg, Bart-Jan, van der Meer, Jos W M, Joosten, Leo A B, Netea, Mihai G
Published in PloS one (07.04.2011)
Published in PloS one (07.04.2011)
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Journal Article
Factors modulating the inflammatory response in acute gouty arthritis
Cleophas, Maartje C, Crişan, Tania O, Joosten, Leo A B
Published in Current opinion in rheumatology (01.03.2017)
Published in Current opinion in rheumatology (01.03.2017)
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Journal Article
Immune Profiling of Patients with Systemic Sclerosis through Targeted Proteomic Analysis
Szabo, Iulia, Badii, Medeea, Gaál, Ildikó O, Szabo, Robert, Sîrbe, Claudia, Humiță, Oana, Joosten, Leo A B, Crișan, Tania O, Rednic, Simona
Published in International journal of molecular sciences (18.12.2023)
Published in International journal of molecular sciences (18.12.2023)
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Journal Article
Enhanced Innate and Acquired Immune Responses in Systemic Sclerosis Primary Peripheral Blood Mononuclear Cells (PBMCs)
Szabo, Iulia, Badii, Medeea, Gaál, Ildikó O., Szabo, Robert, Popp, Radu A., Joosten, Leo A. B., Crişan, Tania O., Rednic, Simona
Published in International journal of molecular sciences (01.10.2023)
Published in International journal of molecular sciences (01.10.2023)
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Journal Article
Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases
Cleophas, Maartje C P, Crişan, Tania O, Lemmers, Heidi, Toenhake-Dijkstra, Helga, Fossati, Gianluca, Jansen, Tim L, Dinarello, Charles A, Netea, Mihai G, Joosten, Leo A B
Published in Annals of the rheumatic diseases (01.03.2016)
Published in Annals of the rheumatic diseases (01.03.2016)
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Journal Article
Detection of Novel Biomarkers in Pediatric Autoimmune Hepatitis by Proteomic Profiling
Sîrbe, Claudia, Badii, Medeea, Crişan, Tania O, Bența, Gabriel, Grama, Alina, Joosten, Leo A B, Rednic, Simona, Pop, Tudor Lucian
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Journal Article
TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells
Klück, Viola, Cabău, Georgiana, Mies, Linda, Bukkems, Femke, van Emst, Liesbeth, Bakker, René, van Caam, Arjan, Crişan, Tania O, Joosten, Leo A B
Published in Arthritis research & therapy (27.02.2023)
Published in Arthritis research & therapy (27.02.2023)
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Journal Article
Trained immunity and inflammation in rheumatic diseases
Badii, Medeea, Gaal, Orsolya, Popp, Radu A., Crișan, Tania O., Joosten, Leo A.B.
Published in Joint, bone, spine : revue du rhumatisme (01.07.2022)
Published in Joint, bone, spine : revue du rhumatisme (01.07.2022)
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Journal Article
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2
Plantinga, Theo S, Crisan, Tania O, Oosting, Marije, van de Veerdonk, Frank L, de Jong, Dirk J, Philpott, Dana J, van der Meer, Jos W M, Girardin, Stephen E, Joosten, Leo A B, Netea, Mihai G
Published in Gut (01.09.2011)
Published in Gut (01.09.2011)
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Journal Article
Soluble urate-induced effects on cytokine production in vitro - Assessment of methodologies and cell types
Liu, Ruiqi, Klück, Viola, Kischkel, Brenda, Tercan, Helin, Netea, Mihai G, Crişan, Tania O, Joosten, Leo A B
Published in Cytokine (Philadelphia, Pa.) (01.03.2024)
Published in Cytokine (Philadelphia, Pa.) (01.03.2024)
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Journal Article
Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra
Crișan, Tania O, Cleophas, Maartje C P, Oosting, Marije, Lemmers, Heidi, Toenhake-Dijkstra, Helga, Netea, Mihai G, Jansen, Tim L, Joosten, Leo A B
Published in Annals of the rheumatic diseases (01.04.2016)
Published in Annals of the rheumatic diseases (01.04.2016)
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Journal Article
Downregulation of type I interferon signalling pathway by urate in primary human PBMCs
Badii, Medeea, Nica, Valentin, Straton, Ancuța R, Kischkel, Brenda, Gaal, Orsolya, Cabău, Georgiana, Klück, Viola, Hotea, Ioana, Novakovic, Boris, Pamfil, Cristina, Rednic, Simona, Netea, Mihai G, Popp, Radu A, Joosten, Leo A B, Crișan, Tania O
Published in Immunology (01.10.2024)
Published in Immunology (01.10.2024)
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Journal Article
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout
Klück, Viola, van Deuren, Rosanne C, Cavalli, Giulio, Shaukat, Amara, Arts, Peer, Cleophas, Maartje C, Crișan, Tania O, Tausche, Anne-Kathrin, Riches, Philip, Dalbeth, Nicola, Stamp, Lisa K, Hindmarsh, Jennie Harré, Jansen, Tim L Th A, Janssen, Matthijs, Steehouwer, Marloes, Lelieveld, Stefan, van de Vorst, Maartje, Gilissen, Christian, Dagna, Lorenzo, Van de Veerdonk, Frank L, Eisenmesser, Elan Z, Kim, SooHyun, Merriman, Tony R, Hoischen, Alexander, Netea, Mihai G, Dinarello, Charles A, Joosten, Leo AB
Published in Annals of the rheumatic diseases (01.04.2020)
Published in Annals of the rheumatic diseases (01.04.2020)
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