Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase‑2 as Targeted Optical Imaging Agents
Uddin, Md. Jashim, Crews, Brenda C, Ghebreselasie, Kebreab, Marnett, Lawrence J
Published in Bioconjugate chemistry (17.04.2013)
Published in Bioconjugate chemistry (17.04.2013)
Get full text
Journal Article
Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents
JASHIM UDDIN, Md, CREWS, Brenda C, MARNETT, Lawrence J, BLOBAUM, Anna L, KINGSLEY, Philip J, LEE GORDEN, D, MCINTYRE, J. Oliver, MATRISIAN, Lynn M, SUBBARAMAIAH, Kotha, DANNENBERG, Andrew J, PISTON, David W
Published in Cancer research (Chicago, Ill.) (01.05.2010)
Published in Cancer research (Chicago, Ill.) (01.05.2010)
Get full text
Journal Article
Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6
Brüser, Antje, Zimmermann, Anne, Crews, Brenda C., Sliwoski, Gregory, Meiler, Jens, König, Gabriele M., Kostenis, Evi, Lede, Vera, Marnett, Lawrence J., Schöneberg, Torsten
Published in Scientific reports (24.05.2017)
Published in Scientific reports (24.05.2017)
Get full text
Journal Article
Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold
Liedtke, Andy J, Crews, Brenda C, Daniel, Cristina M, Blobaum, Anna L, Kingsley, Philip J, Ghebreselasie, Kebreab, Marnett, Lawrence J
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
Get full text
Journal Article
nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2
Neumann, Wilma, Xu, Shu, Sárosi, Menyhárt B., Scholz, Matthias S., Crews, Brenda C., Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J., Hey-Hawkins, Evamarie
Published in ChemMedChem (19.01.2016)
Published in ChemMedChem (19.01.2016)
Get full text
Journal Article
Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
Boutaud, Olivier, Sosa, I Romina, Amin, Taneem, Oram, Denise, Adler, David, Hwang, Hyun S, Crews, Brenda C, Milne, Ginger, Harris, Bradford K, Hoeksema, Megan, Knollmann, Bjorn C, Lammers, Philip E, Marnett, Lawrence J, Massion, Pierre P, Oates, John A
Published in Cancer prevention research (Philadelphia, Pa.) (01.11.2016)
Published in Cancer prevention research (Philadelphia, Pa.) (01.11.2016)
Get full text
Journal Article
Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides
Kozak, Kevin R, Crews, Brenda C, Morrow, Jason D, Wang, Lee-Ho, Ma, Y Henry, Weinander, Rolf, Jakobsson, Per-Johan, Marnett, Lawrence J
Published in The Journal of biological chemistry (22.11.2002)
Published in The Journal of biological chemistry (22.11.2002)
Get full text
Journal Article
Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors
Kalgutkar, Amit S, Marnett, Alan B, Crews, Brenda C, Remmel, Rory P, Marnett, Lawrence J
Published in Journal of medicinal chemistry (27.07.2000)
Published in Journal of medicinal chemistry (27.07.2000)
Get full text
Journal Article
Trifluoromethyl Fluorocoxib A Detects Cyclooxygenase‑2 Expression in Inflammatory Tissues and Human Tumor Xenografts
Uddin, Md. Jashim, Crews, Brenda C, Huda, Imran, Ghebreselasie, Kebreab, Daniel, Cristina K, Marnett, Lawrence J
Published in ACS medicinal chemistry letters (10.04.2014)
Published in ACS medicinal chemistry letters (10.04.2014)
Get full text
Journal Article
The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells
Nirodi, Chaitanya S, Crews, Brenda C, Kozak, Kevin R, Morrow, Jason D, Marnett, Lawrence J
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Get full text
Journal Article
Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX‑1 in Ovarian Cancer
Uddin, Md. Jashim, Wilson, Andrew J, Crews, Brenda C, Malerba, Paola, Uddin, Md. Imam, Kingsley, Philip J, Ghebreselasie, Kebreab, Daniel, Cristina K, Nickels, Michael L, Tantawy, Mohammed N, Jashim, Elma, Manning, H. Charles, Khabele, Dineo, Marnett, Lawrence J
Published in ACS omega (31.05.2019)
Published in ACS omega (31.05.2019)
Get full text
Journal Article
Peroxynitrite, the Coupling Product of Nitric Oxide and Superoxide, Activates Prostaglandin Biosynthesis
Landino, Lisa M., Crews, Brenda C., Timmons, Michael D., Morrow, Jason D., Marnett, Lawrence J.
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
Get full text
Journal Article
Biochemically Based Design of Cyclooxygenase-2 (COX-2) Inhibitors: Facile Conversion of Nonsteroidal Antiinflammatory Drugs to Potent and Highly Selective COX-2 Inhibitors
Kalgutkar, Amit S., Crews, Brenda C., Rowlinson, Scott W., Marnett, Alan B., Kozak, Kevin R., Remmel, Rory P., Marnett, Lawrence J.
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2000)
Get full text
Journal Article
In vivo Oxidative Metabolism of a Major Peroxidation-Derived DNA Adduct, M₁dG
Otteneder, Michael B., Knutson, Charles G., Daniels, J. Scott, Hashim, Muhammed, Crews, Brenda C., Remmel, Rory P., Wang, Hao, Rizzo, Carmelo, Marnett, Lawrence J.
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2006)
Get full text
Journal Article
Metabolism in Vitro and in Vivo of the DNA Base Adduct, M1G
Knutson, Charles G, Akingbade, Dapo, Crews, Brenda C, Voehler, Markus, Stec, Donald F, Marnett, Lawrence J
Published in Chemical research in toxicology (01.03.2007)
Published in Chemical research in toxicology (01.03.2007)
Get full text
Journal Article
Conjugation of Cisplatin Analogues and Cyclooxygenase Inhibitors to Overcome Cisplatin Resistance
Neumann, Wilma, Crews, Brenda C., Sárosi, Menyhárt B., Daniel, Cristina M., Ghebreselasie, Kebreab, Scholz, Matthias S., Marnett, Lawrence J., Hey-Hawkins, Evamarie
Published in ChemMedChem (01.01.2015)
Published in ChemMedChem (01.01.2015)
Get full text
Journal Article
Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer
Uddin, Md. Jashim, Werfel, Thomas A, Crews, Brenda C, Gupta, Mukesh K, Kavanaugh, Taylor E, Kingsley, Philip J, Boyd, Kelli, Marnett, Lawrence J, Duvall, Craig L
Published in Biomaterials (01.06.2016)
Published in Biomaterials (01.06.2016)
Get full text
Journal Article
Harmaline Analogs as Substrate-Selective Cyclooxygenase‑2 Inhibitors
Uddin, Md. Jashim, Xu, Shu, Crews, Brenda C, Aleem, Ansari M, Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J
Published in ACS medicinal chemistry letters (08.10.2020)
Published in ACS medicinal chemistry letters (08.10.2020)
Get full text
Journal Article
Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages
Aleem, Ansari M., Kang, Weixi, Lin, Shuyang, Milad, Matthew, Kingsley, Philip J., Crews, Brenda C., Uddin, Md. Jashim, Rouzer, Carol A., Marnett, Lawrence J.
Published in ACS chemical biology (17.02.2023)
Published in ACS chemical biology (17.02.2023)
Get full text
Journal Article