Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges
Terrier, Olivier, Si-Tahar, Mustapha, Ducatez, Mariette, Chevalier, Christophe, Pizzorno, Andrés, Le Goffic, Ronan, Crépin, Thibaut, Simon, Gaëlle, Naffakh, Nadia
Published in PLoS pathogens (30.12.2021)
Published in PLoS pathogens (30.12.2021)
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The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
Bouvier, Denis, McCarthy, Andrew A, Crépin, Thibaut, Cusack, Stephen, Dias, Alexandre, Ruigrok, Rob W. H, Baudin, Florence, Hart, Darren J
Published in Nature (16.04.2009)
Published in Nature (16.04.2009)
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Monomeric nucleoprotein of influenza A virus
Chenavas, Sylvie, Estrozi, Leandro F, Slama-Schwok, Anny, Delmas, Bernard, Di Primo, Carmelo, Baudin, Florence, Li, Xinping, Crépin, Thibaut, Ruigrok, Rob W H
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
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Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria
HERNANDEZ, Vincent, CREPIN, Thibaut, MEEWAN, Maliwan, MOHAN, Manisha, WEIMIN MAO, ROCK, Fernando L, SEXTON, Holly, SHEORAN, Anita, YANCHEN ZHANG, ZHANG, Yong-Kang, ZHOU, Yasheen, NIEMAN, James A, PALENCIA, Andrés, MAHIPAL REDDY ANUGULA, EL MEHDI KERAMANE, SAVARIRAJ, Kingsley, SHEKHAR REDDY, D, SHARMA, Rashmi, SUBEDI, Rajendra, SINGH, Rajeshwar, O'LEARY, Ann, SIMON, Nerissa L, DE MARSH, Peter L, CUSACK, Stephen, MUSHTAQ, Shazad, WARNER, Marina, LIVERMORE, David M, ALLEY, M. R. K, PLATTNER, Jacob J, AKAMA, Tsutomu, BAKER, Stephen J, WEI BU, LISA FENG, FREUND, Yvonne R, LIANG LIU
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
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X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking
Swale, Christopher, Da Costa, Bruno, Sedano, Laura, Garzoni, Frédéric, McCarthy, Andrew A., Berger, Imre, Bieniossek, Christoph, Ruigrok, Rob W.H., Delmas, Bernard, Crépin, Thibaut
Published in Journal of molecular biology (01.05.2020)
Published in Journal of molecular biology (01.05.2020)
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The structural basis for cap binding by influenza virus polymerase subunit PB2
Crepin, Thibaut, Tarendeau, Franck, Resa-Infante, Patricia, Coloma, Rocío, Sehr, Peter, Lewis, Joe, Ruigrok, Rob W H, Guilligay, Delphine, Hart, Darren J, Cusack, Stephen, Ortin, Juan
Published in Nature structural & molecular biology (01.05.2008)
Published in Nature structural & molecular biology (01.05.2008)
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The structure of the nucleoprotein of Influenza D shows that all Orthomyxoviridae nucleoproteins have a similar NPCORE, with or without a NPTAIL for nuclear transport
Donchet, Amélie, Oliva, Justine, Labaronne, Alice, Tengo, Laura, Miloudi, Myriam, C.A. Gerard, Francine, Mas, Caroline, Schoehn, Guy, W.H. Ruigrok, Rob, Ducatez, Mariette, Crépin, Thibaut
Published in Scientific reports (24.01.2019)
Published in Scientific reports (24.01.2019)
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Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein
Guillon, Antoine, Brea‐Diakite, Deborah, Cezard, Adeline, Wacquiez, Alan, Baranek, Thomas, Bourgeais, Jérôme, Picou, Frédéric, Vasseur, Virginie, Meyer, Léa, Chevalier, Christophe, Auvet, Adrien, Carballido, José M, Nadal Desbarats, Lydie, Dingli, Florent, Turtoi, Andrei, Le Gouellec, Audrey, Fauvelle, Florence, Donchet, Amélie, Crépin, Thibaut, Hiemstra, Pieter S, Paget, Christophe, Loew, Damarys, Herault, Olivier, Naffakh, Nadia, Le Goffic, Ronan, Si‐Tahar, Mustapha
Published in The EMBO journal (14.06.2022)
Published in The EMBO journal (14.06.2022)
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Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5
Swale, Christopher, Monod, Alexandre, Tengo, Laura, Labaronne, Alice, Garzoni, Frédéric, Bourhis, Jean-Marie, Cusack, Stephen, Schoehn, Guy, Berger, Imre, Ruigrok, Rob WH, Crépin, Thibaut
Published in Scientific reports (20.04.2016)
Published in Scientific reports (20.04.2016)
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Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing
Tarbouriech, Nicolas, Chenavier, Florian, Kawasaki, Junna, Bachiri, Kamel, Bourhis, Jean-Marie, Legrand, Pierre, Freslon, Lily L, Laurent, Estelle M N, Suberbielle, Elsa, Ruigrok, Rob W H, Tomonaga, Keizo, Gonzalez-Dunia, Daniel, Horie, Masayuki, Coyaud, Etienne, Crépin, Thibaut
Published in Viruses (26.10.2022)
Published in Viruses (26.10.2022)
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Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit
Tarendeau, Franck, Crepin, Thibaut, Guilligay, Delphine, Ruigrok, Rob W H, Cusack, Stephen, Hart, Darren J
Published in PLoS pathogens (01.08.2008)
Published in PLoS pathogens (01.08.2008)
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Mammalian translation elongation factor eEF1A2: X-ray structure and new features of GDP/GTP exchange mechanism in higher eukaryotes
Crepin, Thibaut, Shalak, Vyacheslav F, Yaremchuk, Anna D, Vlasenko, Dmytro O, McCarthy, Andrew, Negrutskii, Boris S, Tukalo, Michail A, El'skaya, Anna V
Published in Nucleic acids research (10.11.2014)
Published in Nucleic acids research (10.11.2014)
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Structural insight into cap-snatching and RNA synthesis by influenza polymerase
Reich, Stefan, Guilligay, Delphine, Pflug, Alexander, Malet, Hélène, Berger, Imre, Crépin, Thibaut, Hart, Darren, Lunardi, Thomas, Nanao, Max, Ruigrok, Rob W. H., Cusack, Stephen
Published in Nature (London) (18.12.2014)
Published in Nature (London) (18.12.2014)
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Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site
Rock, Fernando L, Mao, Weimin, Yaremchuk, Anya, Tukalo, Mikhail, Crépin, Thibaut, Zhou, Huchen, Zhang, Yong-Kang, Hernandez, Vincent, Akama, Tsutomu, Baker, Stephen J, Plattner, Jacob J, Shapiro, Lucy, Martinis, Susan A, Benkovic, Stephen J, Cusack, Stephen, Alley, M.R.K
Published in Science (American Association for the Advancement of Science) (22.06.2007)
Published in Science (American Association for the Advancement of Science) (22.06.2007)
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Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation
Camacho-Zarco, Aldo R., Yu, Lefan, Krischuns, Tim, Dedeoglu, Selin, Maurin, Damien, Bouvignies, Guillaume, Crépin, Thibaut, Ruigrok, Rob W. H., Cusack, Stephan, Naffakh, Nadia, Blackledge, Martin
Published in Journal of the American Chemical Society (27.09.2023)
Published in Journal of the American Chemical Society (27.09.2023)
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Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
Bessonne, Mélissa, Morel, Jessica, Nevers, Quentin, Da Costa, Bruno, Ballandras-Colas, Allison, Chenavier, Florian, Grange, Magali, Roussel, Alain, Crépin, Thibaut, Delmas, Bernard
Published in PLoS pathogens (14.06.2024)
Published in PLoS pathogens (14.06.2024)
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Structure of the Dimerization Domain of the Rabies Virus Phosphoprotein
IVANOV, Ivan, CREPIN, Thibaut, JAMIN, Marc, RUIGROK, Rob W. H
Published in Journal of Virology (01.04.2010)
Published in Journal of Virology (01.04.2010)
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