Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations
Paul, Fabian, Wehmeyer, Christoph, Abualrous, Esam T., Wu, Hao, Crabtree, Michael D., Schöneberg, Johannes, Clarke, Jane, Freund, Christian, Weikl, Thomas R., Noé, Frank
Published in Nature communications (23.10.2017)
Published in Nature communications (23.10.2017)
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Journal Article
Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies
Shammas, Sarah L., Crabtree, Michael D., Dahal, Liza, Wicky, Basile I.M., Clarke, Jane
Published in The Journal of biological chemistry (25.03.2016)
Published in The Journal of biological chemistry (25.03.2016)
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Journal Article
Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein:Target Affinity by Altering the Lifetime of the Bound Complex
Crabtree, Michael D, Borcherds, Wade, Poosapati, Anusha, Shammas, Sarah L, Daughdrill, Gary W, Clarke, Jane
Published in Biochemistry (Easton) (09.05.2017)
Published in Biochemistry (Easton) (09.05.2017)
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Journal Article
Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins
Crabtree, Michael D., Mendonça, Carolina A.T.F., Bubb, Quenton R., Clarke, Jane
Published in The Journal of biological chemistry (22.06.2018)
Published in The Journal of biological chemistry (22.06.2018)
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Journal Article
Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions
Crabtree, Michael D., Holland, Jack, Pillai, Arvind S., Kompella, Purnima S., Babl, Leon, Turner, Noah N., Eaton, James T., Hochberg, Georg K.A., Aarts, Dirk G.A.L., Redfield, Christina, Baldwin, Andrew J., Nott, Timothy J.
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
Bradley, Sophie J, Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J, Thompson, Karen J, Dwomoh, Louis, Sanger, Helen E, Crabtree, Michael D, Brooke, Simon M, Sexton, Patrick M, Felder, Christian C, Christopoulos, Arthur, Broad, Lisa M, Tobin, Andrew B, Langmead, Christopher J
Published in Molecular pharmacology (01.06.2018)
Published in Molecular pharmacology (01.06.2018)
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Journal Article
Bitopic Binding Mode of an M 1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes
Bradley, Sophie J, Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J, Thompson, Karen J, Dwomoh, Louis, Sanger, Helen E, Crabtree, Michael D, Brooke, Simon M, Sexton, Patrick M, Felder, Christian C, Christopoulos, Arthur, Broad, Lisa M, Tobin, Andrew B, Langmead, Christopher J
Published in Molecular pharmacology (01.06.2018)
Published in Molecular pharmacology (01.06.2018)
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Journal Article
A Systematic Review and Meta-Analysis of Single-Incision Versus Multiport Laparoscopic Complete Mesocolic Excision Colectomy for Colon Cancer
Athanasiou, Christos, Pitt, James, Malik, Arshad, Crabtree, Michael, Markides, Georgios A
Published in Surgical innovation (01.04.2020)
Published in Surgical innovation (01.04.2020)
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Journal Article
A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD + Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple-Blind, Placebo-Controlled, Cross-Over Pilot Clinical Trial
Xue, Yongquan, Shamp, Trisha, Nagana Gowda, G A, Crabtree, Michael, Bagchi, Debasis, Raftery, Daniel
Published in Nutrients (26.05.2022)
Published in Nutrients (26.05.2022)
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Journal Article
Author Correction: Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations
Paul, Fabian, Wehmeyer, Christoph, Abualrous, Esam T., Wu, Hao, Crabtree, Michael D., Schöneberg, Johannes, Clarke, Jane, Freund, Christian, Weikl, Thomas R., Noé, Frank
Published in Nature communications (09.03.2018)
Published in Nature communications (09.03.2018)
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Journal Article
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
Harmon, Tyler S., Crabtree, Michael D., Shammas, Sarah L., Posey, Ammon E., Clarke, Jane, Pappu, Rohit V.
Published in Protein engineering, design and selection (01.09.2016)
Published in Protein engineering, design and selection (01.09.2016)
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Journal Article
In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography
Mogg, Adrian J, Eessalu, Thomas, Johnson, Megan, Wright, Rebecca, Sanger, Helen E, Xiao, Hongling, Crabtree, Michael G, Smith, Alex, Colvin, Ellen M, Schober, Douglas, Gehlert, Donald, Jesudason, Cynthia, Goldsmith, Paul J, Johnson, Michael P, Felder, Christian C, Barth, Vanessa N, Broad, Lisa M
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
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Journal Article
Thermodynamic Mapping of Effector Protein Interfaces with RalA and RalB
Campbell, Louise J, Peppa, Maria, Crabtree, Michael D, Shafiq, Arooj, McGough, Nicholas F, Mott, Helen R, Owen, Darerca
Published in Biochemistry (Easton) (17.02.2015)
Published in Biochemistry (Easton) (17.02.2015)
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Journal Article
Mutation Cluster Region, Association Between Germline and Somatic Mutations and Genotype-Phenotype Correlation in Upper Gastrointestinal Familial Adenomatous Polyposis
Groves, Christopher, Lamlum, Hanan, Crabtree, Michael, Williamson, Jill, Taylor, Claire, Bass, Sylvia, Cuthbert-Heavens, Darren, Hodgson, Shirley, Phillips, Robin, Tomlinson, Ian
Published in The American journal of pathology (01.06.2002)
Published in The American journal of pathology (01.06.2002)
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Journal Article
Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients
CRABTREE, Michael, SIEBER, Oliver M, LIPTON, Lara, HODGSON, Shirley V, LAMLUM, Hanan, THOMAS, Hunu J. W, NEALE, Kay, PHILLIPS, Robin K. S, HEINIMANN, Karl, TOMLINSON, Ian P. M
Published in Oncogene (03.07.2003)
Published in Oncogene (03.07.2003)
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Journal Article
RAGE mRNA Expression and Its Correlation with Nuclear Factor Kappa Beta mRNA Expression in Inflamed Human Periradicular Tissues
Crabtree, Michael, DDS, Pileggi, Roberta, DDS, MS, Bhattacharyya, Indraneel, DMD, MS, Caudle, Robert, PhD, Perez, Federico, MS, Riley, Joseph, PhD, Vertucci, Frank, DMD, Katz, Joseph, DMD
Published in Journal of endodontics (01.06.2008)
Published in Journal of endodontics (01.06.2008)
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Journal Article
Better cloning through expression
Crabtree, Michael D.
Published in Science (American Association for the Advancement of Science) (19.12.2014)
Published in Science (American Association for the Advancement of Science) (19.12.2014)
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Journal Article