The hCMEC/D3 cell line as a model of the human blood brain barrier
Weksler, Babette, Romero, Ignacio A, Couraud, Pierre-Olivier
Published in Fluids and barriers of the CNS (26.03.2013)
Published in Fluids and barriers of the CNS (26.03.2013)
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The blood-brain barrier in brain homeostasis and neurological diseases
Weiss, Nicolas, Miller, Florence, Cazaubon, Sylvie, Couraud, Pierre-Olivier
Published in Biochimica et biophysica acta (01.04.2009)
Published in Biochimica et biophysica acta (01.04.2009)
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Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Luissint, Anny-Claude, Artus, Cédric, Glacial, Fabienne, Ganeshamoorthy, Kayathiri, Couraud, Pierre-Olivier
Published in Fluids and barriers of the CNS (09.11.2012)
Published in Fluids and barriers of the CNS (09.11.2012)
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Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells
Ochiai, Yusuke, Uchida, Yasuo, Tachikawa, Masanori, Couraud, Pierre‐Olivier, Terasaki, Tetsuya
Published in Journal of neurochemistry (01.08.2019)
Published in Journal of neurochemistry (01.08.2019)
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Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
Shawahna, Ramzi, Uchida, Yasuo, Declèves, Xavier, Ohtsuki, Sumio, Yousif, Salah, Dauchy, Sandrine, Jacob, Aude, Chassoux, Francine, Daumas-Duport, Catherine, Couraud, Pierre-Olivier, Terasaki, Tetsuya, Scherrmann, Jean-Michel
Published in Molecular pharmaceutics (01.08.2011)
Published in Molecular pharmaceutics (01.08.2011)
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Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models
Hatherell, Kathryn, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Pilkington, Geoffrey J.
Published in Journal of neuroscience methods (15.08.2011)
Published in Journal of neuroscience methods (15.08.2011)
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Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood–brain barrier
Hoshi, Yutaro, Uchida, Yasuo, Tachikawa, Masanori, Ohtsuki, Sumio, Couraud, Pierre-Olivier, Suzuki, Takashi, Terasaki, Tetsuya
Published in Journal of cerebral blood flow and metabolism (01.02.2020)
Published in Journal of cerebral blood flow and metabolism (01.02.2020)
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Differential effects of hydrocortisone and TNFα on tight junction proteins in an in vitro model of the human blood–brain barrier
Förster, Carola, Burek, Malgorzata, Romero, Ignacio A., Weksler, Babette, Couraud, Pierre‐Olivier, Drenckhahn, Detlev
Published in The Journal of physiology (01.04.2008)
Published in The Journal of physiology (01.04.2008)
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Journal Article
human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies
Poller, Birk, Gutmann, Heike, Krähenbühl, Stephan, Weksler, Babette, Romero, Ignacio, Couraud, Pierre-Olivier, Tuffin, Gerald, Drewe, Jürgen, Huwyler, Jörg
Published in Journal of neurochemistry (01.12.2008)
Published in Journal of neurochemistry (01.12.2008)
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Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis
Uchida, Yasuo, Sumiya, Tomohito, Tachikawa, Masanori, Yamakawa, Tatsuya, Murata, Sho, Yagi, Yuta, Sato, Kazuki, Stephan, Alice, Ito, Katsuaki, Ohtsuki, Sumio, Couraud, Pierre-Olivier, Suzuki, Takashi, Terasaki, Tetsuya
Published in Molecular neurobiology (01.03.2019)
Published in Molecular neurobiology (01.03.2019)
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Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood–brain barrier transporters
Hoshi, Yutaro, Uchida, Yasuo, Kuroda, Takashi, Tachikawa, Masanori, Couraud, Pierre-Olivier, Suzuki, Takashi, Terasaki, Tetsuya
Published in Journal of cerebral blood flow and metabolism (01.07.2020)
Published in Journal of cerebral blood flow and metabolism (01.07.2020)
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Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging
Li, Tengfei, Bourgeois, Jean-Pierre, Celli, Susanna, Glacial, Fabienne, Le Sourd, Anne-Marie, Mecheri, Salah, Weksler, Babette, Romero, Ignacio, Couraud, Pierre-Olivier, Rougeon, François, Lafaye, Pierre
Published in The FASEB journal (01.10.2012)
Published in The FASEB journal (01.10.2012)
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Astrocytes facilitate melanoma brain metastasis via secretion of IL-23
Klein, Anat, Schwartz, Hila, Sagi-Assif, Orit, Meshel, Tsipi, Izraely, Sivan, Ben Menachem, Shlomit, Bengaiev, Roman, Ben-Shmuel, Amir, Nahmias, Clara, Couraud, Pierre-Olivier, Witz, Isaac P, Erez, Neta
Published in The Journal of pathology (01.05.2015)
Published in The Journal of pathology (01.05.2015)
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Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model
Ohtsuki, Sumio, Ikeda, Chiemi, Uchida, Yasuo, Sakamoto, Yumi, Miller, Florence, Glacial, Fabienne, Decleves, Xavier, Scherrmann, Jean-Michel, Couraud, Pierre-Olivier, Kubo, Yoshiyuki, Tachikawa, Masanori, Terasaki, Tetsuya
Published in Molecular pharmaceutics (07.01.2013)
Published in Molecular pharmaceutics (07.01.2013)
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Primary Angiitis of the Central Nervous System: Description of the First Fifty‐Two Adults Enrolled in the French Cohort of Patients With Primary Vasculitis of the Central Nervous System
Boysson, Hubert, Zuber, Mathieu, Naggara, Olivier, Neau, Jean‐Philippe, Gray, Françoise, Bousser, Marie‐Germaine, Crassard, Isabelle, Touzé, Emmanuel, Couraud, Pierre‐Olivier, Kerschen, Philippe, Oppenheim, Catherine, Detante, Olivier, Faivre, Anthony, Gaillard, Nicolas, Arquizan, Caroline, Bienvenu, Boris, Néel, Antoine, Guillevin, Loïc, Pagnoux, Christian
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2014)
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The Wnt/Planar Cell Polarity Signaling Pathway Contributes to the Integrity of Tight Junctions in Brain Endothelial Cells
Artus, Cédric, Glacial, Fabienne, Ganeshamoorthy, Kayathiri, Ziegler, Nicole, Godet, Maeva, Guilbert, Thomas, Liebner, Stefan, Couraud, Pierre-Olivier
Published in Journal of cerebral blood flow and metabolism (01.03.2014)
Published in Journal of cerebral blood flow and metabolism (01.03.2014)
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Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4
Duperray, Alain, Barbe, Delphin, Raguenez, Gilda, Weksler, Babette B, Romero, Ignacio A, Couraud, Pierre-Olivier, Perron, Hervé, Marche, Patrice N
Published in International immunology (01.11.2015)
Published in International immunology (01.11.2015)
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Cyclocreatine Transport by SLC6A8, the Creatine Transporter, in HEK293 Cells, a Human Blood-Brain Barrier Model Cell, and CCDSs Patient-Derived Fibroblasts
Uemura, Tatsuki, Ito, Shingo, Masuda, Takeshi, Shimbo, Hiroko, Goto, Tomohide, Osaka, Hitoshi, Wada, Takahito, Couraud, Pierre-Olivier, Ohtsuki, Sumio
Published in Pharmaceutical research (01.03.2020)
Published in Pharmaceutical research (01.03.2020)
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