Search Results - "COTTAM, HOWARD B" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses

Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses

by Goff, Peter H, Hayashi, Tomoko, Martínez-Gil, Luis, Corr, Maripat, Crain, Brian, Yao, Shiyin, Cottam, Howard B, Chan, Michael, Ramos, Irene, Eggink, Dirk, Heshmati, Mitra, Krammer, Florian, Messer, Karen, Pu, Minya, Fernandez-Sesma, Ana, Palese, Peter, Carson, Dennis A
Published in Journal of virology (01.03.2015)

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Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides

Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides

by Shinchi, Hiroyuki, Crain, Brian, Yao, Shiyin, Chan, Michael, Zhang, Shannon S, Ahmadiiveli, Alast, Suda, Yasuo, Hayashi, Tomoko, Cottam, Howard B, Carson, Dennis A
Published in Bioconjugate chemistry (19.08.2015)

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Structure–Activity Relationship Studies of Pyrimido[5,4‑b]indoles as Selective Toll-Like Receptor 4 Ligands

Structure–Activity Relationship Studies of Pyrimido[5,4‑b]indoles as Selective Toll-Like Receptor 4 Ligands

by Chan, Michael, Kakitsubata, Yuhei, Hayashi, Tomoko, Ahmadi, Alast, Yao, Shiyin, Shukla, Nikunj M, Oyama, Shin-ya, Baba, Akihito, Nguyen, Brandon, Corr, Maripat, Suda, Yasuo, Carson, Dennis A, Cottam, Howard B, Wakao, Masahiro
Published in Journal of medicinal chemistry (22.11.2017)

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Identification of Substituted Pyrimido[5,4‑b]indoles as Selective Toll-Like Receptor 4 Ligands

Identification of Substituted Pyrimido[5,4‑b]indoles as Selective Toll-Like Receptor 4 Ligands

by Chan, Michael, Hayashi, Tomoko, Mathewson, Richard D, Nour, Afshin, Hayashi, Yuki, Yao, Shiyin, Tawatao, Rommel I, Crain, Brian, Tsigelny, Igor F, Kouznetsova, Valentina L, Messer, Karen, Pu, Minya, Corr, Maripat, Carson, Dennis A, Cottam, Howard B
Published in Journal of medicinal chemistry (13.06.2013)

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Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

by Wu, Raymond P., Hayashi, Tomoko, Cottam, Howard B., Jin, Guangyi, Yao, Shiyin, Wu, Christina C. N., Rosenbach, Michael D., Corr, Maripat, Schwab, Richard B., Carson, Dennis A.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2010)

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Synthesis and immunostimulatory activity of sugar-conjugated TLR7 ligands

Synthesis and immunostimulatory activity of sugar-conjugated TLR7 ligands

by Baba, Akihito, Wakao, Masahiro, Shinchi, Hiroyuki, Chan, Michael, Hayashi, Tomoko, Yao, Shiyin, Cottam, Howard B., Carson, Dennis A., Suda, Yasuo
Published in Bioorganic & medicinal chemistry letters (01.02.2020)

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Molecular Basis for the Immunostimulatory Activity of Guanine Nucleoside Analogs: Activation of Toll-like Receptor 7

Molecular Basis for the Immunostimulatory Activity of Guanine Nucleoside Analogs: Activation of Toll-like Receptor 7

by Lee, Jongdae, Chuang, Tsung-Hsien, Redecke, Vanessa, She, Liping, Pitha, Paula M., Carson, Dennis A., Raz, Eyal, Cottam, Howard B.
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)

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Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release

Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release

by Shpigelman, Jonathan, Lao, Fitzgerald S, Yao, Shiyin, Li, Chenyang, Saito, Tetsuya, Sato-Kaneko, Fumi, Nolan, John P, Shukla, Nikunj M, Pu, Minya, Messer, Karen, Cottam, Howard B, Carson, Dennis A, Corr, Maripat, Hayashi, Tomoko
Published in Frontiers in pharmacology (16.04.2021)

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A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity

A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity

by Sato-Kaneko, Fumi, Yao, Shiyin, Lao, Fitzgerald S, Shpigelman, Jonathan, Messer, Karen, Pu, Minya, Shukla, Nikunj M, Cottam, Howard B, Chan, Michael, Chu, Paul J, Burkhart, David, Schoener, Roman, Matsutani, Takaji, Carson, Dennis A, Corr, Maripat, Hayashi, Tomoko
Published in Frontiers in immunology (19.06.2020)

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Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes

by Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Promessi, Victor J, Shyu, Luke, Sheng, Caroline, Kang, McNancy, Cottam, Howard B, Carson, Dennis A, Corr, Maripat
Published in PloS one (15.06.2015)

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Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses

Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses

by Abdelwahab, Walid M, Auclair, Sarah, Borgogna, Timothy, Siram, Karthik, Riffey, Alexander, Bazin, Hélène G, Cottam, Howard B, Hayashi, Tomoko, Evans, Jay T, Burkhart, David J
Published in Pharmaceutics (01.01.2024)

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Activation of the Wnt Signaling Pathway in Chronic Lymphocytic Leukemia

Activation of the Wnt Signaling Pathway in Chronic Lymphocytic Leukemia

by Lu, Desheng, Zhao, Yandong, Tawatao, Rommel, Cottam, Howard B., Sen, Malini, Leoni, Lorenzo M., Kipps, Thomas J., Corr, Maripat, Carson, Dennis A.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)

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A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity

A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity

by Shukla, Nikunj M, Sato-Kaneko, Fumi, Yao, Shiyin, Pu, Minya, Chan, Michael, Lao, Fitzgerald S, Sako, Yukiya, Saito, Tetsuya, Messer, Karen, Hayashi, Tomoko, Cottam, Howard B, Corr, Maripat, Carson, Dennis A
Published in Frontiers in pharmacology (11.04.2022)

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Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge

Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge

by Saito, Tetsuya, Sako, Yukiya, Sato-Kaneko, Fumi, Hosoya, Tadashi, Yao, Shiyin, Lao, Fitzgerald S, Shpigelman, Jonathan, Messer, Karen, Pu, Minya, Shukla, Nikunj M, Chan, Michael, Chu, Paul J, Cottam, Howard B, Hayashi, Tomoko, Carson, Dennis A, Corr, Maripat
Published in Frontiers in immunology (28.09.2021)

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Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes

by Hosoya, Tadashi, Shukla, Nikunj M, Fujita, Yuya, Yao, Shiyin, Lao, Fitzgerald S, Baba, Hiroyuki, Yasuda, Shinsuke, Cottam, Howard B, Carson, Dennis A, Hayashi, Tomoko, Corr, Maripat
Published in Frontiers in pharmacology (17.12.2020)

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Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

Synthesis and Immunological Characterization of Toll-Like Receptor 7 Agonistic Conjugates

by Chan, Michael, Hayashi, Tomoko, Kuy, Crystal S, Gray, Christine S, Wu, Christina C. N, Corr, Maripat, Wrasidlo, Wolfgang, Cottam, Howard B, Carson, Dennis A
Published in Bioconjugate chemistry (17.06.2009)

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Activation of Anti-Hepatitis C Virus Responses via Toll-like Receptor 7

Activation of Anti-Hepatitis C Virus Responses via Toll-like Receptor 7

by Lee, Jongdae, Wu, Christina C. N., Lee, Ki Jeong, Chuang, Tsung-Hsien, Katakura, Kyoko, Liu, Yu-Tsueng, Chan, Michael, Tawatao, Rommel, Chung, Michelle, Shen, Carol, Cottam, Howard B., Lai, Michael M. C., Raz, Eyal, Carson, Dennis A.
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)

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A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination

A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination

by Sato-Kaneko, Fumi, Yao, Shiyin, Lao, Fitzgerald S, Sako, Yukiya, Jin, Jasmine, Shukla, Nikunj M, Cottam, Howard B, Chan, Michael, Belsuzarri, Masiel M, Carson, Dennis A, Hayashi, Tomoko
Published in Vaccines (Basel) (01.10.2022)

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Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

by Wu, Christina C.N, Hayashi, Tomoko, Takabayashi, Kenji, Sabet, Mojgan, Smee, Donald F, Guiney, Donald D, Cottam, Howard B, Carson, Dennis A
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2007)

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Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system

Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system

by Hayashi, Tomoko, Yao, Shiyin, Crain, Brian, Chan, Michael, Tawatao, Rommel I, Gray, Christine, Vuong, Linda, Lao, Fitzgerald, Cottam, Howard B, Carson, Dennis A, Corr, Maripat
Published in PloS one (28.09.2012)

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