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Published in Current medicinal chemistry (01.01.2015)
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Published in Journal of medicinal chemistry (25.06.2015)
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Published in Chembiochem : a European journal of chemical biology (14.05.2021)
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Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities
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Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors
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Polito, Maria Pia, Romaldini, Alessio, Tagliazucchi, Lorenzo, Marini, Grazia, Radice, Federica, Gozza, Gaia Andrea, Bergamini, Giulia, Costi, Maria Paola, Enzo, Elena
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TRAP1: a viable therapeutic target for future cancer treatments?
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Published in Expert opinion on therapeutic targets (03.08.2017)
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Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase
Tassone, Giusy, Landi, Giacomo, Linciano, Pasquale, Francesconi, Valeria, Tonelli, Michele, Tagliazucchi, Lorenzo, Costi, Maria Paola, Mangani, Stefano, Pozzi, Cecilia
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Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics
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Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors
Pozzi, Cecilia, Ferrari, Stefania, Luciani, Rosaria, Costi, Maria Paola, Mangani, Stefano
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Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells
MARVERTI, GAETANO, LIGABUE, ALESSIO, LOMBARDI, PAOLO, FERRARI, STEFANIA, MONTI, MARIA GIUSEPPINA, FRASSINETI, CHIARA, COSTI, MARIA PAOLA
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A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells
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Published in International journal of molecular sciences (23.06.2020)
Published in International journal of molecular sciences (23.06.2020)
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Cavazzuti, Antonio, Paglietti, Giuseppe, Hunter, William N, Gamarro, Francisco, Piras, Sandra, Loriga, Mario, Allecca, Sergio, Corona, Paola, McLuskey, Karen, Tulloch, Lindsay, Gibellini, Federica, Ferrari, Stefania, Costi, Maria Paola
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
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Design, Synthesis and Antiparasitic Evaluation of Click Phospholipids
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Published in Molecules (Basel, Switzerland) (10.07.2021)
Published in Molecules (Basel, Switzerland) (10.07.2021)
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Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth
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Published in Molecules (Basel, Switzerland) (26.09.2019)
Published in Molecules (Basel, Switzerland) (26.09.2019)
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Oxaliplatin plus leucovorin and 5-fluorouracil (FOLFOX-4) as a salvage chemotherapy in heavily-pretreated platinum-resistant ovarian cancer
Conteduca, Vincenza, Gurioli, Giorgia, Rossi, Lorena, Scarpi, Emanuela, Lolli, Cristian, Schepisi, Giuseppe, Farolfi, Alberto, De Lisi, Delia, Gallà, Valentina, Burgio, Salvatore Luca, Menna, Cecilia, Amadori, Andrea, Losi, Lorena, Amadori, Dino, Costi, Maria Paola, De Giorgi, Ugo
Published in BMC cancer (19.12.2018)
Published in BMC cancer (19.12.2018)
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