Assessing Environmental Risks during the Drug Development Process for Parasitic Vector-Borne Diseases: A Critical Reflection
Ilbeigi, Kayhan, Barata, Carlos, Barbosa, João, Bertram, Michael G., Caljon, Guy, Costi, Maria Paola, Kroll, Alexandra, Margiotta-Casaluci, Luigi, Thoré, Eli S.J., Bundschuh, Mirco
Published in ACS infectious diseases (12.04.2024)
Published in ACS infectious diseases (12.04.2024)
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Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents
Francesconi, Valeria, Rizzo, Marco, Pozzi, Cecilia, Tagliazucchi, Lorenzo, Konchie Simo, Claude U., Saporito, Giulia, Landi, Giacomo, Mangani, Stefano, Carbone, Anna, Schenone, Silvia, Santarém, Nuno, Tavares, Joana, Cordeiro-da-Silva, Anabela, Costi, Maria Paola, Tonelli, Michele
Published in ACS infectious diseases (09.08.2024)
Published in ACS infectious diseases (09.08.2024)
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The Hippo Pathway and YAP/TAZ–TEAD Protein–Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment: Miniperspective
Santucci, Matteo, Vignudelli, Tatiana, Ferrari, Stefania, Mor, Marco, Scalvini, Laura, Bolognesi, Maria Laura, Uliassi, Elisa, Costi, Maria Paola
Published in Journal of medicinal chemistry (25.06.2015)
Published in Journal of medicinal chemistry (25.06.2015)
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Journal Article
Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase
Salo-Ahen, Outi M. H, Tochowicz, Anna, Pozzi, Cecilia, Cardinale, Daniela, Ferrari, Stefania, Boum, Yap, Mangani, Stefano, Stroud, Robert M, Saxena, Puneet, Myllykallio, Hannu, Costi, Maria Paola, Ponterini, Glauco, Wade, Rebecca C
Published in Journal of medicinal chemistry (23.04.2015)
Published in Journal of medicinal chemistry (23.04.2015)
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Journal Article
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds
Borsari, Chiara, Santarem, Nuno, Torrado, Juan, Olías, Ana Isabel, Corral, María Jesús, Baptista, Catarina, Gul, Sheraz, Wolf, Markus, Kuzikov, Maria, Ellinger, Bernhard, Witt, Gesa, Gribbon, Philip, Reinshagen, Jeanette, Linciano, Pasquale, Tait, Annalisa, Costantino, Luca, Freitas-Junior, Lucio H., Moraes, Carolina B., Bruno dos Santos, Pascoalino, Alcântara, Laura Maria, Franco, Caio Haddad, Bertolacini, Claudia Danielli, Fontana, Vanessa, Tejera Nevado, Paloma, Clos, Joachim, Alunda, José María, Cordeiro-da-Silva, Anabela, Ferrari, Stefania, Costi, Maria Paola
Published in European journal of medicinal chemistry (27.01.2017)
Published in European journal of medicinal chemistry (27.01.2017)
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Journal Article
Optimization of Peptides That Target Human Thymidylate Synthase to Inhibit Ovarian Cancer Cell Growth
Pelà, Michela, Saxena, Puneet, Luciani, Rosaria, Santucci, Matteo, Ferrari, Stefania, Marverti, Gaetano, Marraccini, Chiara, Martello, Andrea, Pirondi, Silvia, Genovese, Filippo, Salvadori, Severo, D’Arca, Domenico, Ponterini, Glauco, Costi, Maria Paola, Guerrini, Remo
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Journal Article
Design, synthesis and biological evaluation of non-covalent AmpC β-lactamases inhibitors
Genovese, Filippo, Lazzari, Sandra, Venturi, Ettore, Costantino, Luca, Blazquez, Jesus, Ibacache-Quiroga, Claudia, Costi, Maria Paola, Tondi, Donatella
Published in Medicinal chemistry research (01.05.2017)
Published in Medicinal chemistry research (01.05.2017)
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Journal Article
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance
Tagliazucchi, Lorenzo, Pinetti, Diego, Genovese, Filippo, Malpezzi, Giulia, Perea Martinez, Ana, Manzano, José I., García-Hernández, Raquel, Cole, Alexander R., Kwon, Ba Reum, Aiello, Daniele, Brooks, Bryan W., Thoré, Eli S. J., Bertram, Michael G., Gamarro, Francisco, Costi, Maria Paola
Published in ACS infectious diseases (13.09.2024)
Published in ACS infectious diseases (13.09.2024)
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Journal Article
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes
Piras, Sandra, Carta, Antonio, Briguglio, Irene, Corona, Paola, Paglietti, Giuseppe, Luciani, Rosaria, Costi, Maria Paola, Ferrari, Stefania
Published in European journal of medicinal chemistry (21.03.2014)
Published in European journal of medicinal chemistry (21.03.2014)
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Journal Article
Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
Uliassi, Elisa, Piazzi, Lorna, Belluti, Federica, Mazzanti, Andrea, Kaiser, Marcel, Brun, Reto, Moraes, Carolina B., Freitas‐Junior, Lucio H., Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, Borsari, Chiara, Costi, Maria Paola, Bolognesi, Maria Laura
Published in ChemMedChem (06.04.2018)
Published in ChemMedChem (06.04.2018)
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Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology
Ponterini, Glauco, Martello, Andrea, Pavesi, Giorgia, Lauriola, Angela, Luciani, Rosaria, Santucci, Matteo, Pelà, Michela, Gozzi, Gaia, Pacifico, Salvatore, Guerrini, Remo, Marverti, Gaetano, Costi, Maria Paola, D’Arca, Domenico
Published in Scientific reports (02.06.2016)
Published in Scientific reports (02.06.2016)
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Journal Article
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase‑1 Inhibitors
Landi, Giacomo, Linciano, Pasquale, Borsari, Chiara, Bertolacini, Claudia P, Moraes, Carolina B, Cordeiro-da-Silva, Anabela, Gul, Sheraz, Witt, Gesa, Kuzikov, Maria, Costi, Maria Paola, Pozzi, Cecilia, Mangani, Stefano
Published in ACS infectious diseases (12.07.2019)
Published in ACS infectious diseases (12.07.2019)
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Journal Article
Internalization and Stability of a Thymidylate Synthase Peptide Inhibitor in Ovarian Cancer Cells
Cannazza, Giuseppe, Cazzato, Addolorata Stefania, Marraccini, Chiara, Pavesi, Giorgia, Pirondi, Silvia, Guerrini, Remo, Pelà, Michela, Frassineti, Chiara, Ferrari, Stefania, Marverti, Gaetano, Ponterini, Glauco, Costi, Maria Paola
Published in Journal of medicinal chemistry (26.12.2014)
Published in Journal of medicinal chemistry (26.12.2014)
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Journal Article
Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides
Genovese, Filippo, Gualandi, Alessandra, Taddia, Laura, Marverti, Gaetano, Pirondi, Silvia, Marraccini, Chiara, Perco, Paul, Pelà, Michela, Guerrini, Remo, Amoroso, Maria Rosaria, Esposito, Franca, Martello, Andrea, Ponterini, Glauco, D’Arca, Domenico, Costi, Maria Paola
Published in Journal of proteome research (07.11.2014)
Published in Journal of proteome research (07.11.2014)
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Journal Article
Correction to “Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides”
Genovese, Filippo, Gualandi, Alessandra, Taddia, Laura, Marverti, Gaetano, Pirondi, Silvia, Marraccini, Chiara, Perco, Paul, Pelà, Michela, Guerrini, Remo, Amoroso, Maria Rosaria, Esposito, Franca, Martello, Andrea, Ponterini, Glauco, D’Arca, Domenico, Costi, Maria Paola
Published in Journal of proteome research (07.10.2016)
Published in Journal of proteome research (07.10.2016)
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Journal Article
Feasibility Study on a Measurement Method and a Portable Measuring System to Estimate the Concentration of Cloxacillin and β-Lactamase in Milk
Venturelli, Alberto, Luciani, Rosaria, Costi, Maria Paola, Rovati, Luigi, Ferrari, Luca, Cattini, Stefano
Published in Journal of sensors (01.01.2017)
Published in Journal of sensors (01.01.2017)
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Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells
Marverti, Gaetano, Guaitoli, Giambattista, Ligabue, Alessio, Frassineti, Chiara, Monti, Maria Giuseppina, Lombardi, Paolo, Costi, Maria Paola
Published in Amino acids (01.02.2012)
Published in Amino acids (01.02.2012)
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Journal Article
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells
Marverti, Gaetano, Ligabue, Alessio, Paglietti, Giuseppe, Corona, Paola, Piras, Sandra, Vitale, Gabriella, Guerrieri, Davide, Luciani, Rosaria, Costi, Maria Paola, Frassineti, Chiara, Moruzzi, Maria Stella
Published in European journal of pharmacology (01.08.2009)
Published in European journal of pharmacology (01.08.2009)
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Journal Article
SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent
Borsari, Chiara, Santarem, Nuno, Macedo, Sara, Jiménez-Antón, María Dolores, Torrado, Juan J, Olías-Molero, Ana Isabel, Corral, María J, Tait, Annalisa, Ferrari, Stefania, Costantino, Luca, Luciani, Rosaria, Ponterini, Glauco, Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, Behrens, Birte, Reinshagen, Jeanette, Alunda, José María, Cordeiro-da-Silva, Anabela, Costi, Maria Paola
Published in ACS medicinal chemistry letters (11.04.2019)
Published in ACS medicinal chemistry letters (11.04.2019)
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Journal Article
Structural study of phenyl boronic acid derivatives as AmpC b-lactamase inhibitors
Tondi, Donatella, Calo, Samuele, Shoichet, Brian K, Costi, Maria Paola
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
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