GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function
Zaïmia, Nour, Obeid, Joelle, Varrault, Annie, Sabatier, Julia, Broca, Christophe, Gilon, Patrick, Costes, Safia, Bertrand, Gyslaine, Ravier, Magalie A.
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions
Brown, Matthew R, Laouteouet, Damien, Delobel, Morgane, Villard, Orianne, Broca, Christophe, Bertrand, Gyslaine, Wojtusciszyn, Anne, Dalle, Stéphane, Ravier, Magalie A, Matveyenko, Aleksey V, Costes, Safia
Published in Cell death & disease (15.04.2022)
Published in Cell death & disease (15.04.2022)
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Journal Article
The CDK4-pRB-E2F1 pathway controls insulin secretion
Annicotte, Jean-Sébastien, Blanchet, Emilie, Chavey, Carine, Iankova, Irena, Costes, Safia, Assou, Said, Teyssier, Jacques, Dalle, Stéphane, Sardet, Claude, Fajas, Lluis
Published in Nature cell biology (01.08.2009)
Published in Nature cell biology (01.08.2009)
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Journal Article
Calcium-activated Calpain-2 Is a Mediator of Beta Cell Dysfunction and Apoptosis in Type 2 Diabetes
Huang, Chang-jiang, Gurlo, Tatyana, Haataja, Leena, Costes, Safia, Daval, Marie, Ryazantsev, Sergey, Wu, Xiuji, Butler, Alexandra E., Butler, Peter C.
Published in The Journal of biological chemistry (01.01.2010)
Published in The Journal of biological chemistry (01.01.2010)
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Journal Article
Degradation of cAMP-Responsive Element–Binding Protein by the Ubiquitin-Proteasome Pathway Contributes to Glucotoxicity in β-Cells and Human Pancreatic Islets
COSTES, Safia, VANDEWALLE, Brigitte, DALLE, Stéphane, TOURREL-CUZIN, Cécile, BROCA, Christophe, LINCK, Nathalie, BERTRAND, Gyslaine, KERR-CONTE, Julie, PORTHA, Bernard, PATTOU, François, BOCKAERT, Joel
Published in Diabetes (New York, N.Y.) (01.05.2009)
Published in Diabetes (New York, N.Y.) (01.05.2009)
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Journal Article
ERK1/2 Control Phosphorylation and Protein Level of cAMP-Responsive Element–Binding Protein
Costes, Safia, Broca, Christophe, Bertrand, Gyslaine, Lajoix, Anne-Dominique, Bataille, Dominique, Bockaert, Joel, Dalle, Stéphane
Published in Diabetes (New York, N.Y.) (01.08.2006)
Published in Diabetes (New York, N.Y.) (01.08.2006)
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Journal Article
Glucagon Promotes cAMP-response Element-binding Protein Phosphorylation via Activation of ERK1/2 in MIN6 Cell Line and Isolated Islets of Langerhans
Dalle, Stéphane, Longuet, Christine, Costes, Safia, Broca, Christophe, Faruque, Omar, Fontés, Ghislaine, Hani, El Habib, Bataille, Dominique
Published in The Journal of biological chemistry (07.05.2004)
Published in The Journal of biological chemistry (07.05.2004)
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Journal Article
Activation of Melatonin Signaling Promotes β-Cell Survival and Function
Costes, Safia, Boss, Marti, Thomas, Anthony P, Matveyenko, Aleksey V
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2015)
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2015)
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Journal Article
β-Cell Failure in Type 2 Diabetes: A Case of Asking Too Much of Too Few?
COSTES, Safia, LANGEN, Ralf, GURLO, Tatyana, MATVEYENKO, Aleksey V, BUTLER, Peter C
Published in Diabetes (New York, N.Y.) (01.02.2013)
Published in Diabetes (New York, N.Y.) (01.02.2013)
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Journal Article
Erratum. β-Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide–Induced UCH-L1 Deficiency. Diabetes 2011;60:227–238
Costes, Safia, Huang, Chang-jiang, Gurlo, Tatyana, Daval, Marie, Matveyenko, Aleksey V., Rizza, Robert A., Butler, Alexandra E., Butler, Peter C.
Published in Diabetes (New York, N.Y.) (01.12.2023)
Published in Diabetes (New York, N.Y.) (01.12.2023)
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Journal Article
GLP-1 Mediates Antiapoptotic Effect by Phosphorylating Bad through a β-Arrestin 1-mediated ERK1/2 Activation in Pancreatic β-Cells
Quoyer, Julie, Longuet, Christine, Broca, Christophe, Linck, Nathalie, Costes, Safia, Varin, Elodie, Bockaert, Joël, Bertrand, Gyslaine, Dalle, Stéphane
Published in The Journal of biological chemistry (15.01.2010)
Published in The Journal of biological chemistry (15.01.2010)
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Journal Article
325-LB: Circadian Clock Nuclear Receptor REV-ERBa Is a Novel Regulator of Beta-Cell Function, Survival, and Autophagy under Diabetogenic Conditions
COSTES, SAFIA, LAOUTEOUET, DAMIEN, RAVIER, MAGALIE A., DELOBEL, MORGANE, BERTRAND, GYSLAINE, DALLE, STéPHANE, MATVEYENKO, ALEKSEY
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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Journal Article
β-Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide-Induced UCH-L1 Deficiency
COSTES, Safia, HUANG, Chang-Jiang, GURLO, Tatyana, DAVAL, Marie, MATVEYENKO, Aleksey V, RIZZA, Robert A, BUTLER, Alexandra E, BUTLER, Peter C
Published in Diabetes (New York, N.Y.) (01.01.2011)
Published in Diabetes (New York, N.Y.) (01.01.2011)
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Journal Article
Cyclin-Dependent Kinase 5 Promotes Pancreatic β-Cell Survival via Fak-Akt Signaling Pathways
DAVAL, Marie, GURLO, Tatyana, COSTES, Safia, HUANG, Chang-Jiang, BUTLER, Peter C
Published in Diabetes (New York, N.Y.) (01.04.2011)
Published in Diabetes (New York, N.Y.) (01.04.2011)
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Journal Article
ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB
Leduc, Michele, Richard, Joy, Costes, Safia, Muller, Dany, Varrault, Annie, Compan, Vincent, Mathieu, Julia, Tanti, Jean-François, Pagès, Gilles, Pouyssegur, Jacques, Bertrand, Gyslaine, Dalle, Stéphane, Ravier, Magalie A.
Published in Diabetologia (01.10.2017)
Published in Diabetologia (01.10.2017)
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