Next-Generation Machine Learning for Biological Networks
Camacho, Diogo M., Collins, Katherine M., Powers, Rani K., Costello, James C., Collins, James J.
Published in Cell (14.06.2018)
Published in Cell (14.06.2018)
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GSEA-InContext: identifying novel and common patterns in expression experiments
Powers, Rani K, Goodspeed, Andrew, Pielke-Lombardo, Harrison, Tan, Aik-Choon, Costello, James C
Published in Bioinformatics (01.07.2018)
Published in Bioinformatics (01.07.2018)
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Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics
Goodspeed, Andrew, Heiser, Laura M, Gray, Joe W, Costello, James C
Published in Molecular cancer research (01.01.2016)
Published in Molecular cancer research (01.01.2016)
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Journal Article
Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells
Kalghatgi, Sameer, Spina, Catherine S, Costello, James C, Liesa, Marc, Morones-Ramirez, J Ruben, Slomovic, Shimyn, Molina, Anthony, Shirihai, Orian S, Collins, James J
Published in Science translational medicine (03.07.2013)
Published in Science translational medicine (03.07.2013)
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Crowdsourcing biomedical research: leveraging communities as innovation engines
Saez-Rodriguez, Julio, Costello, James C, Friend, Stephen H, Kellen, Michael R, Mangravite, Lara, Meyer, Pablo, Norman, Thea, Stolovitzky, Gustavo
Published in Nature reviews. Genetics (01.08.2016)
Published in Nature reviews. Genetics (01.08.2016)
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Journal Article
Wisdom of crowds for robust gene network inference
Marbach, Daniel, Costello, James C, Küffner, Robert, Vega, Nicole M, Prill, Robert J, Camacho, Diogo M, Allison, Kyle R, Kellis, Manolis, Collins, James J, Stolovitzky, Gustavo
Published in Nature methods (15.07.2012)
Published in Nature methods (15.07.2012)
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TERT promoter mutations and telomerase reactivation in urothelial cancer
Borah, Sumit, Xi, Linghe, Zaug, Arthur J., Powell, Natasha M., Dancik, Garrett M., Cohen, Scott B., Costello, James C., Theodorescu, Dan, Cech, Thomas R.
Published in Science (American Association for the Advancement of Science) (27.02.2015)
Published in Science (American Association for the Advancement of Science) (27.02.2015)
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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia
Pei, Shanshan, Pollyea, Daniel A, Gustafson, Annika, Stevens, Brett M, Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A, Gillen, Austin E, Sheridan, Ryan M, Kim, Jihye, Costello, James C, Amaya, Maria L, Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L, Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R, Ashton, John M, Nemkov, Travis, D'Alessandro, Angelo, Gutman, Jonathan A, Ramsey, Haley E, Savona, Michael R, Smith, Clayton A, Jordan, Craig T
Published in Cancer discovery (01.04.2020)
Published in Cancer discovery (01.04.2020)
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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
Powers, Rani K, Culp-Hill, Rachel, Ludwig, Michael P, Smith, Keith P, Waugh, Katherine A, Minter, Ross, Tuttle, Kathryn D, Lewis, Hannah C, Rachubinski, Angela L, Granrath, Ross E, Carmona-Iragui, María, Wilkerson, Rebecca B, Kahn, Darcy E, Joshi, Molishree, Lleó, Alberto, Blesa, Rafael, Fortea, Juan, D'Alessandro, Angelo, Costello, James C, Sullivan, Kelly D, Espinosa, Joaquin M
Published in Nature communications (18.10.2019)
Published in Nature communications (18.10.2019)
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Journal Article
Metastatic cells are preferentially vulnerable to lysosomal inhibition
Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2018)
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Journal Article
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
Kwong, Lawrence N, Costello, James C, Liu, Huiyun, Jiang, Shan, Helms, Timothy L, Langsdorf, Aliete E, Jakubosky, David, Genovese, Giannicola, Muller, Florian L, Jeong, Joseph H, Bender, Ryan P, Chu, Gerald C, Flaherty, Keith T, Wargo, Jennifer A, Collins, James J, Chin, Lynda
Published in Nature medicine (01.10.2012)
Published in Nature medicine (01.10.2012)
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Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes
Stern, Josh Lewis, Paucek, Richard D., Huang, Franklin W., Ghandi, Mahmoud, Nwumeh, Ronald, Costello, James C., Cech, Thomas R.
Published in Cell reports (Cambridge) (26.12.2017)
Published in Cell reports (Cambridge) (26.12.2017)
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Magnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials
Arias-Lorza, Andrés M, Costello, James R, Hingorani, Sunil R, Von Hoff, Daniel D, Korn, Ronald L, Raghunand, Natarajan
Published in Scientific reports (21.05.2024)
Published in Scientific reports (21.05.2024)
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Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer
Nickerson, Michael L, Dancik, Garrett M, Im, Kate M, Edwards, Michael G, Turan, Sevilay, Brown, Joseph, Ruiz-Rodriguez, Christina, Owens, Charles, Costello, James C, Guo, Guangwu, Tsang, Shirley X, Li, Yingrui, Zhou, Quan, Cai, Zhiming, Moore, Lee E, Lucia, M Scott, Dean, Michael, Theodorescu, Dan
Published in Clinical cancer research (15.09.2014)
Published in Clinical cancer research (15.09.2014)
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Incidence and Risk Factors for Gadolinium-Based Contrast Agent Immediate Reactions
Costello, James R, Kalb, Bobby, Martin, Diego R
Published in Topics in magnetic resonance imaging (01.12.2016)
Published in Topics in magnetic resonance imaging (01.12.2016)
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Journal Article
GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis
Agarwal, Neeraj, Dancik, Garrett M, Goodspeed, Andrew, Costello, James C, Owens, Charles, Duex, Jason E, Theodorescu, Dan
Published in Cancer research (Chicago, Ill.) (01.09.2016)
Published in Cancer research (Chicago, Ill.) (01.09.2016)
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