The therapeutical potential of a novel pterocarpanquinone LQB-118 to target inhibitor of apoptosis proteins in acute myeloid leukemia cells
de Souza Reis, Flaviana R, de Faria, Fernanda C Casal, Castro, Carolina P, de Souza, Paloma S, da Cunha Vasconcelos, Flavia, Bello, Reinaldo D, da Silva, Alcides J, Costa, Paulo R R, Maia, Raquel C
Published in Anti-cancer agents in medicinal chemistry (01.02.2013)
Published in Anti-cancer agents in medicinal chemistry (01.02.2013)
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The pterocarpanquinone LQB‑118 compound induces apoptosis of cytarabine‑resistant acute myeloid leukemia cells
Hancio, Thaís, Mazzoccoli, Luciano, Guimarães, Gustavo, Robaina, Marcela, Mendonça, Bruna Dos Santos, Nestal De Moraes, Gabriela, Monte-Mor, Barbara Da Costa Reis, Mayumi Gutiyama, Luciana, De Carvalho, Luíze Otero, Netto, Chaquip Daher, Costa, Paulo R R, De Faria, Fernanda Costas Casal, Maia, Raquel Ciuvalschi
Published in International journal of oncology (01.06.2021)
Published in International journal of oncology (01.06.2021)
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LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells
Bernardo, Paula Sabbo, Guimarães, Gustavo Henrique C, De Faria, Fernanda Costas C, Longo, Gabriel M Da Cunha, Lopes, Giselle P De Faria, Netto, Chaquip Daher, Costa, Paulo R R, Maia, Raquel C
Published in Oncology reports (01.01.2020)
Published in Oncology reports (01.01.2020)
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Insights into the Biological Evaluation of Pterocarpanquinones and Carbapterocarpans with Anti-tumor Activity against MDR Leukemias
Rumjanek, Vivian M, Maia, Raquel C, Salustiano, Eduardo J, Costa, Paulo R R
Published in Anti-cancer agents in medicinal chemistry (01.01.2019)
Published in Anti-cancer agents in medicinal chemistry (01.01.2019)
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Bifunctional primary amine 2-aminobenzimidazole organocatalyst anchored to trans-cyclohexane-1,2-diamine in enantioselective conjugate additions of aldehydes
Fernandes, Talita de A., Vizcaíno-Milla, Pascuala, Ravasco, João M.J.M., Ortega-Martínez, Aitor, Sansano, José M., Nájera, Carmen, Costa, Paulo R.R., Fiser, Béla, Gómez-Bengoa, Enrique
Published in Tetrahedron: asymmetry (15.02.2016)
Published in Tetrahedron: asymmetry (15.02.2016)
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Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors
Kaushik-Basu, Neerja, Bopda-Waffo, Alain, Talele, Tanaji T, Basu, Amartya, Costa, Paulo R.R, da Silva, Alcides J.M, Sarafianos, Stefan G, Noël, François
Published in Nucleic acids research (01.03.2008)
Published in Nucleic acids research (01.03.2008)
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Binap-silver salts as chiral catalysts for the enantioselective 1,3-dipolar cycloaddition of azomethine ylides and alkenes
Mancebo-Aracil, Juan, Martín-Rodríguez, María, Nájera, Carmen, Sansano, José M., Costa, Paulo R.R., de Lima, Evanoel Crizanto, Dias, Ayres G.
Published in Tetrahedron: asymmetry (15.12.2012)
Published in Tetrahedron: asymmetry (15.12.2012)
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11a-N-tosyl-5-carbapterocarpans: Synthesis, antineoplastic evaluation and in silico prediction of ADMETox properties
Mendes, Joseane A., Salustiano, Eduardo J., Pires, Carulini de S., Oliveira, Thaís, Barcellos, Julio C.F., Cifuentes, Jhonny M.C., Costa, Paulo R.R., Rennó, Magdalena N., Buarque, Camilla D.
Published in Bioorganic chemistry (01.10.2018)
Published in Bioorganic chemistry (01.10.2018)
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The pterocarpanquinone LQB 118 induces apoptosis in tumor cells through the intrinsic pathway and the endoplasmic reticulum stress pathway
de Sá Bacelar, Thiago, da Silva, Alcides J, Costa, Paulo R R, Rumjanek, Vivian M
Published in Anti-cancer drugs (01.01.2013)
Published in Anti-cancer drugs (01.01.2013)
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NFκB pathway and microRNA-9 and -21 are involved in sensitivity to the pterocarpanquinone LQB-118 in different CML cell lines
de Faria, Fernanda Costas C, Leal, Maria Eduarda Bento, Bernardo, Paula Sabbo, Costa, Paulo R R, Maia, Raquel C
Published in Anti-cancer agents in medicinal chemistry (01.01.2015)
Published in Anti-cancer agents in medicinal chemistry (01.01.2015)
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Palladium-catalyzed oxyarylation of olefins using silver carbonate as the base. Probing the mechanism by electrospray ionization mass spectrometry
Buarque, Camilla D., Pinho, Vagner D., Vaz, Boniek Gontijo, Eberlin, Marcos N., da Silva, Alcides J.M., Costa, Paulo R.R.
Published in Journal of organometallic chemistry (15.08.2010)
Published in Journal of organometallic chemistry (15.08.2010)
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Reactive Oxygen Species Release, Alkylating Ability, and DNA Interactions of a Pterocarpanquinone: A Test Case for Electrochemistry
Silva, Thaissa L., Ferreira, Fabricia R., de Vasconcelos, Camila C., da Silva, Rosanny Christhinny, Lima, Dimas José da P., Costa, Paulo R. R., Netto, Chaquip D., Goulart, Marília O. F.
Published in ChemElectroChem (01.12.2016)
Published in ChemElectroChem (01.12.2016)
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Synthesis and preliminary pharmacological evaluation of new (±) 1,4-naphthoquinones structurally related to lapachol
DA SILVA, Alcides J. M, BUARQUE, Camilla D, SILVA, Noelson M. V, MELO, Paulo A, CARUSO, Rodrigo R. B, CASTRO, Newton G, COSTA, Paulo R. R, BRITO, Flavia V, AURELIAN, Laure, MACEDO, Luciana F, MALKAS, Linda H, HICKEY, Robert J, LOPES, Daniele V. S, NOËL, Francois, MURAKAMI, Yugo L. B
Published in Bioorganic & medicinal chemistry (01.08.2002)
Published in Bioorganic & medicinal chemistry (01.08.2002)
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Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation
DA SILVA, Alcides J. M, MELO, Paulo A, COSTA, Paulo R. R, SILVA, Noelson M. V, BRITO, Flavia V, BUARQUE, Camilla D, DE SOUZA, Daniele V, RODRIGUES, Veronica P, POCAS, Elisa S. C, NOËL, Francois, ALBUQUERQUE, Edson X
Published in Bioorganic & medicinal chemistry letters (12.02.2001)
Published in Bioorganic & medicinal chemistry letters (12.02.2001)
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Stereoselective preparation of pyrrolidin-2-ones from a Z-enoate derived from d-(+)-mannitol
Domingos, Jorge L.O, Lima, Evanoel C, Dias, Ayres G, Costa, Paulo R.R
Published in Tetrahedron: asymmetry (09.08.2004)
Published in Tetrahedron: asymmetry (09.08.2004)
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Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor
Lopes, Daniele V.S, Caruso, Rodrigo R.B, Castro, Newton G, Costa, Paulo R.R, da Silva, Alcides J.M, Noël, François
Published in European journal of pharmacology (14.07.2004)
Published in European journal of pharmacology (14.07.2004)
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Ru(II)-Catalyzed Asymmetric Transfer Hydrogenation of Chalcones in Water: Application to the Enantioselective Synthesis of Flavans BW683C and Tephrowatsin E
Demidoff, Felipe C., Caleffi, Guilherme S., Figueiredo, Marcella, Costa, Paulo R. R.
Published in Journal of organic chemistry (04.11.2022)
Published in Journal of organic chemistry (04.11.2022)
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