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Hauschild, Janet, Petersen, Bjoern, Santiago, Yolanda, Queisser, Anna-Lisa, Carnwath, Joseph W, Lucas-Hahn, Andrea, Zhang, Lei, Meng, Xiangdong, Gregory, Philip D, Schwinzer, Reinhard, Cost, Gregory J, Niemann, Heiner
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Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2011)
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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells
Hoban, Megan D., Cost, Gregory J., Mendel, Matthew C., Romero, Zulema, Kaufman, Michael L., Joglekar, Alok V., Ho, Michelle, Lumaquin, Dianne, Gray, David, Lill, Georgia R., Cooper, Aaron R., Urbinati, Fabrizia, Senadheera, Shantha, Zhu, Allen, Liu, Pei-Qi, Paschon, David E., Zhang, Lei, Rebar, Edward J., Wilber, Andrew, Wang, Xiaoyan, Gregory, Philip D., Holmes, Michael C., Reik, Andreas, Hollis, Roger P., Kohn, Donald B.
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In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration
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Published in Biotechnology and bioengineering (01.03.2013)
Published in Biotechnology and bioengineering (01.03.2013)
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Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
Geurts, Aron M, Cost, Gregory J, Freyvert, Yevgeniy, Zeitler, Bryan, Miller, Jeffrey C, Choi, Vivian M, Jenkins, Shirin S, Wood, Adam, Cui, Xiaoxia, Meng, Xiangdong, Vincent, Anna, Lam, Stephen, Michalkiewicz, Mieczyslaw, Schilling, Rebecca, Foeckler, Jamie, Kalloway, Shawn, Weiler, Hartmut, Ménoret, Séverine, Anegon, Ignacio, Davis, Gregory D, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Jacob, Howard J, Buelow, Roland
Published in Science (American Association for the Advancement of Science) (24.07.2009)
Published in Science (American Association for the Advancement of Science) (24.07.2009)
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Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation
Sexton, Alec N, Regalado, Samuel G, Lai, Christine S, Cost, Gregory J, O'Neil, Colleen M, Urnov, Fyodor D, Gregory, Philip D, Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk
Published in Genes & development (01.09.2014)
Published in Genes & development (01.09.2014)
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Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes
Aliaga Goltsman, Daniela S., Alexander, Lisa M., Lin, Jyun-Liang, Fregoso Ocampo, Rodrigo, Freeman, Benjamin, Lamothe, Rebecca C., Perez Rivas, Andres, Temoche-Diaz, Morayma M., Chadha, Shailaja, Nordenfelt, Natalie, Janson, Owen P., Barr, Ian, Devoto, Audra E., Cost, Gregory J., Butterfield, Cristina N., Thomas, Brian C., Brown, Christopher T.
Published in Nature communications (15.12.2022)
Published in Nature communications (15.12.2022)
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Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells
Forster, Ryan, Chiba, Kunitoshi, Schaeffer, Lorian, Regalado, Samuel G., Lai, Christine S., Gao, Qing, Kiani, Samira, Farin, Henner F., Clevers, Hans, Cost, Gregory J., Chan, Andy, Rebar, Edward J., Urnov, Fyodor D., Gregory, Philip D., Pachter, Lior, Jaenisch, Rudolf, Hockemeyer, Dirk
Published in Stem cell reports (03.06.2014)
Published in Stem cell reports (03.06.2014)
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Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases
Remy, Séverine, Tesson, Laurent, Menoret, Séverine, Usal, Claire, De Cian, Anne, Thepenier, Virginie, Thinard, Reynald, Baron, Daniel, Charpentier, Marine, Renaud, Jean-Baptiste, Buelow, Roland, Cost, Gregory J, Giovannangeli, Carine, Fraichard, Alexandre, Concordet, Jean-Paul, Anegon, Ignacio
Published in Genome research (01.08.2014)
Published in Genome research (01.08.2014)
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Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases
Liu, Pei-Qi, Chan, Edmond M, Cost, Gregory J, Zhang, Lin, Wang, Jianbin, Miller, Jeffrey C, Guschin, Dmitry Y, Reik, Andreas, Holmes, Michael C, Mott, John E, Collingwood, Trevor N, Gregory, Philip D
Published in Biotechnology and bioengineering (01.05.2010)
Published in Biotechnology and bioengineering (01.05.2010)
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Generation of gene-specific mutated rats using zinc-finger nucleases
Geurts, Aron M, Cost, Gregory J, Rémy, Séverine, Cui, Xiaoxia, Tesson, Laurent, Usal, Claire, Ménoret, Séverine, Jacob, Howard J, Anegon, Ignacio, Buelow, Roland
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2010)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2010)
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Characterization of immunoglobulin heavy chain knockout rats
Ménoret, Séverine, Iscache, Anne-L, Tesson, Laurent, Rémy, Séverine, Usal, Claire, Osborn, Michel J, Cost, Gregory J, Brüggemann, Marianne, Buelow, Roland, Anegon, Ignacio
Published in European journal of immunology (01.10.2010)
Published in European journal of immunology (01.10.2010)
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Sequence-Directed DNA Translocation by Purified FtsK
Pease, Paul J, Levy, Oren, Cost, Gregory J, Gore, Jeff, Ptacin, Jerod L, Sherratt, David, Bustamante, Carlos, Cozzarelli, Nicholas R
Published in Science (American Association for the Advancement of Science) (28.01.2005)
Published in Science (American Association for the Advancement of Science) (28.01.2005)
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Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency
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Published in Hepatology communications (01.03.2023)
Published in Hepatology communications (01.03.2023)
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Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability
Alexander, Lisa M, Aliaga Goltsman, Daniela S, Liu, Jason, Lin, Jyun-Liang, Temoche-Diaz, Morayma M, Laperriere, Sarah M, Neerincx, Andreas, Bednarski, Christien, Knyphausen, Philipp, Cohnen, Andre, Albers, Justine, Gonzalez-Osorio, Liliana, Fregoso Ocampo, Rodrigo, Oki, Jennifer, Devoto, Audra E, Castelle, Cindy J, Lamothe, Rebecca C, Cost, Gregory J, Butterfield, Cristina N, Thomas, Brian C, Brown, Christopher T
Published in CRISPR journal (01.06.2023)
Published in CRISPR journal (01.06.2023)
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Retrotransposon overdose and genome integrity
Scheifele, Lisa Z, Cost, Gregory J, Zupancic, Margaret L, Caputo, Emerita M, Boeke, Jef D
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2009)
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Genetic engineering of human pluripotent cells using TALE nucleases
Jaenisch, Rudolf, Hockemeyer, Dirk, Wang, Haoyi, Kiani, Samira, Lai, Christine S, Gao, Qing, Cassady, John P, Cost, Gregory J, Zhang, Lei, Santiago, Yolanda, Miller, Jeffrey C, Zeitler, Bryan, Cherone, Jennifer M, Meng, Xiangdong, Hinkley, Sarah J, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D
Published in Nature biotechnology (01.08.2011)
Published in Nature biotechnology (01.08.2011)
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Knockout rats generated by embryo microinjection of TALENs
Tesson, Laurent, Usal, Claire, Ménoret, Séverine, Leung, Elo, Niles, Brett J, Remy, Séverine, Santiago, Yolanda, Vincent, Anna I, Meng, Xiangdong, Zhang, Lei, Gregory, Philip D, Anegon, Ignacio, Cost, Gregory J
Published in Nature biotechnology (01.08.2011)
Published in Nature biotechnology (01.08.2011)
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A TALE nuclease architecture for efficient genome editing
Rebar, Edward J, Miller, Jeffrey C, Tan, Siyuan, Qiao, Guijuan, Barlow, Kyle A, Wang, Jianbin, Xia, Danny F, Meng, Xiangdong, Paschon, David E, Leung, Elo, Hinkley, Sarah J, Dulay, Gladys P, Hua, Kevin L, Ankoudinova, Irina, Cost, Gregory J, Urnov, Fyodor D, Zhang, H Steve, Holmes, Michael C, Zhang, Lei, Gregory, Philip D
Published in Nature biotechnology (01.02.2011)
Published in Nature biotechnology (01.02.2011)
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Dissection of splicing regulation at an endogenous locus by zinc-finger nuclease-mediated gene editing
Cristea, Sandra, Gregory, Philip D, Urnov, Fyodor D, Cost, Gregory J
Published in PloS one (08.02.2011)
Published in PloS one (08.02.2011)
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