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BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency
Pache, Lars, Dutra, Miriam S., Spivak, Adam M., Marlett, John M., Murry, Jeffrey P., Hwang, Young, Maestre, Ana M., Manganaro, Lara, Vamos, Mitchell, Teriete, Peter, Martins, Laura J., König, Renate, Simon, Viviana, Bosque, Alberto, Fernandez-Sesma, Ana, Cosford, Nicholas D.P., Bushman, Frederic D., Young, John A.T., Planelles, Vicente, Chanda, Sumit K.
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Kim, InKi, Shu, Chih-Wen, Xu, Wenjie, Shiau, Chung-Wai, Grant, Daniel, Vasile, Stefan, Cosford, Nicholas D.P., Reed, John C.
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Barnes, Samuel A., Sheffler, Douglas J., Semenova, Svetlana, Cosford, Nicholas D.P., Bespalov, Anton
Published in Biological psychiatry (1969) (01.06.2018)
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Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo
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Identification and Development of a New Positron Emission Tomography Ligand 4‑(2-Fluoro-4‑[11C]methoxyphenyl)-5-((1-methyl‑1H‑pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)
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Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
Noberini, Roberta, Koolpe, Mitchell, Peddibhotla, Satyamaheshwar, Dahl, Russell, Su, Ying, Cosford, Nicholas D.P., Roth, Gregory P., Pasquale, Elena B.
Published in The Journal of biological chemistry (24.10.2008)
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Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis
Welsh, Kate, Milutinovic, Snezana, Ardecky, Robert J, Gonzalez-Lopez, Marcos, Ganji, Santhi Reddy, Teriete, Peter, Finlay, Darren, Riedl, Stefan, Matsuzawa, Shu-Ichi, Pinilla, Clemencia, Houghten, Richard, Vuori, Kristiina, Reed, John C, Cosford, Nicholas D P
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Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor
Pinkerton, Anthony B., Sergienko, Eduard, Bravo, Yalda, Dahl, Russell, Ma, Chen-Ting, Sun, Qing, Jackson, Michael R., Cosford, Nicholas D.P., Millán, José Luis
Published in Bioorganic & medicinal chemistry letters (01.01.2018)
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Detection of Cellular Target Engagement for Small-Molecule Modulators of Striatal-Enriched Protein Tyrosine Phosphatase (STEP)
Han, Ye Na, Lambert, Lester J, De Backer, Laurent J S, Wu, Jiaqian, Cosford, Nicholas D P, Tautz, Lutz
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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Targeting Unc51-like Autophagy Activating Kinase 1 (ULK1) Overcomes Adaptive Drug Resistance in Acute Myelogenous Leukemia
Bhattacharya, Seemana, Piya, Sujan, Ma, Huaxian, Sharma, Priyanka, Zhang, Qi, Baran, Natalia, Ruvolo, Vivian R, McQueen, Teresa, Davis, R Eric, Pourebrahim, Rasoul, Konopleva, Marina, Kantarjian, Hagop, Cosford, Nicholas D P, Andreeff, Michael, Borthakur, Gautam
Published in Molecular cancer research (01.06.2023)
Published in Molecular cancer research (01.06.2023)
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