Search Results - "CORTEZ GUILLERMO S" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

by Bonday, Zahid Q., Cortez, Guillermo S., Grogan, Michael J., Antonysamy, Stephen, Weichert, Ken, Bocchinfuso, Wayne P., Li, Fengling, Kennedy, Steven, Li, Binghui, Mader, Mary M., Arrowsmith, Cheryl H., Brown, Peter J., Eram, Mohammad S., Szewczyk, Magdalena M., Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Guccione, Ernesto, Campbell, Robert M.
Published in ACS medicinal chemistry letters (12.07.2018)

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Journal Article

Studies of zoanthamine alkaloids. A general scheme for the preparation of functionalized 8-oxa-6-azabicyclo[3.2.1]octanes

Studies of zoanthamine alkaloids. A general scheme for the preparation of functionalized 8-oxa-6-azabicyclo[3.2.1]octanes

by Williams, David R., Patnaik, Samarjit, Cortez, Guillermo S.
Published in Heterocycles (13.04.2007)

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Journal Article

Discovery of dual positive allosteric modulators (PAMs) of the metabotropic glutamate 2 receptor and CysLT1 antagonists for treating migraine headache

Discovery of dual positive allosteric modulators (PAMs) of the metabotropic glutamate 2 receptor and CysLT1 antagonists for treating migraine headache

by Blanco, Maria-Jesus, Benesh, Dana R., Knobelsdorf, James A., Khilevich, Albert, Cortez, Guillermo S., Mokube, Fese, Aicher, Thomas D., Groendyke, Todd M., Marmsater, Fredrik P., Tang, Tony P., Johnson, Kirk W., Clemens-Smith, Amy, Muhlhauser, Mark A., Swanson, Steven, Catlow, John, Emkey, Renee, Johnson, Michael P., Schkeryantz, Jeffrey M.
Published in Bioorganic & medicinal chemistry letters (15.01.2017)

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Journal Article

Asymmetric Synthesis of Bicyclic β-Lactones via the Intramolecular, Nucleophile-Catalyzed Aldol Lactonization: Improved Efficiency and Expanded Scope

Asymmetric Synthesis of Bicyclic β-Lactones via the Intramolecular, Nucleophile-Catalyzed Aldol Lactonization: Improved Efficiency and Expanded Scope

by Oh, Seong Ho, Cortez, Guillermo S, Romo, Daniel
Published in Journal of organic chemistry (01.04.2005)

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Journal Article

Intramolecular, Nucleophile-Catalyzed Aldol-Lactonization (NCAL) Reactions: Catalytic, Asymmetric Synthesis of Bicyclic β-Lactones

Intramolecular, Nucleophile-Catalyzed Aldol-Lactonization (NCAL) Reactions: Catalytic, Asymmetric Synthesis of Bicyclic β-Lactones

by Cortez, Guillermo S, Tennyson, Reginald L, Romo, Daniel
Published in Journal of the American Chemical Society (15.08.2001)

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Journal Article

Nucleophilic openings of bicyclic β-lactones via acyl C–O and alkyl C–O cleavage: catalytic, asymmetric synthesis of a versatile, carbocyclic nucleoside precursor and protected transpentacin

Nucleophilic openings of bicyclic β-lactones via acyl C–O and alkyl C–O cleavage: catalytic, asymmetric synthesis of a versatile, carbocyclic nucleoside precursor and protected transpentacin

by Yokota, Yasuno, Cortez, Guillermo S, Romo, Daniel
Published in Tetrahedron (26.08.2002)

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Journal Article

Studies of zoanthamine alkaloids. Enantiocontrolled construction of the tetracyclic hemi-aminal core

Studies of zoanthamine alkaloids. Enantiocontrolled construction of the tetracyclic hemi-aminal core

by Williams, David R., Cortez, Guillermo S.
Published in Tetrahedron letters (30.04.1998)

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Journal Article

A β-Lactone Route to Chiral γ-Substituted α-Amino Acids: Application to the Concise Synthesis of (S)-α-Azidobutyro Lactone and a Natural Amino Acid

A β-Lactone Route to Chiral γ-Substituted α-Amino Acids: Application to the Concise Synthesis of (S)-α-Azidobutyro Lactone and a Natural Amino Acid

by Tennyson, Reginald L, Cortez, Guillermo S, Galicia, Héctor J, Kreiman, Charles R, Thompson, Christina M, Romo, Daniel
Published in Organic letters (21.02.2002)

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Journal Article

ERK [23-c]-4- THIENO[23-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

ERK [23-c]-4- THIENO[23-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

by JOSEPH SAJAN, MCMILLEN WILLIAM T, ZHAO GAIYING, CORTEZ GUILLERMO S, MCLEAN JOHNATHAN ALEXANDER, RODRIGUEZ MICHAEL JOHN
Year of Publication 17.07.2017

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Patent

5'-치환된 뉴클레오시드 유사체

5'-치환된 뉴클레오시드 유사체

by DAHNKE KARL ROBERT, GROGAN MICHAEL JOHN, HERGUETA ANTONIO RODRIGUEZ, WATSON BRIAN MORGAN, CORTEZ GUILLERMO S, JAMISON JAMES ANDREW, BONDAY ZAHID QUYOOM, WOODS TIMOTHY ANDREW
Year of Publication 04.12.2017

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Patent

Total Synthesis of Lankacyclinol Generous financial support for this research was provided by the National Institutes of Health (Award no.: GM41560). Additionally, a National Institutes of Health Minority Predoctoral Fellowship (Award no.: GM18547) to G.S.C. is gratefully acknowledged. We also wish to thank Dr. Tsuneaki Hida and Dr. Yoshio Kozai, Takeda Chemical Ltd. (Japan), for providing us with an authentic sample of lankacyclinol as well as copies of the original (1)H NMR spectrum

Total Synthesis of Lankacyclinol Generous financial support for this research was provided by the National Institutes of Health (Award no.: GM41560). Additionally, a National Institutes of Health Minority Predoctoral Fellowship (Award no.: GM18547) to G.S.C. is gratefully acknowledged. We also wish to thank Dr. Tsuneaki Hida and Dr. Yoshio Kozai, Takeda Chemical Ltd. (Japan), for providing us with an authentic sample of lankacyclinol as well as copies of the original (1)H NMR spectrum

by Williams, David R., Cortez, Guillermo S., Bogen, Stéphane L., Rojas, Christian M.
Published in Angewandte Chemie International Edition (15.12.2000)

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Journal Article

SELF-HYDROLYZING MALEIMIDES FOR BIOCONJUGATION

SELF-HYDROLYZING MALEIMIDES FOR BIOCONJUGATION

by ALAM, Riazul, CORTEZ, Guillermo S, WANG, Yan
Year of Publication 02.05.2024

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Patent

Bicyclic beta-lactones via intramolecular NCAL reactions with cinchona alkaloids: Effect of the C9-substituent on enantioselectivity and catalyst conformation

Bicyclic beta-lactones via intramolecular NCAL reactions with cinchona alkaloids: Effect of the C9-substituent on enantioselectivity and catalyst conformation

by Cortez, GS, Oh, SH, Romo, D
Published in Synthesis (Stuttgart) (2001)

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Journal Article

Total Synthesis of Lankacyclinol

Total Synthesis of Lankacyclinol

by Williams, David R., Cortez, Guillermo S., Bogen, Stéphane L., Rojas, Christian M.
Published in Angewandte Chemie (International ed.) (15.12.2000)

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Journal Article

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

by ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 12.09.2024

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Patent

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

by ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 30.05.2024

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Patent

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

LONG-ACTING NATRIURETIC PEPTIDES AND USES THEREOF

by ALSINA-FERNANDEZ, Jorge, CORTEZ, Guillermo S, LIU, Wen, WANG, Yan, ELMUCCIO, Michael Lawrence, BAKER, Hana Elisabeth, LOPES, Daniel Christopher, VALENZUELA, Francisco Alcides, MUPPIDI, Avinash, ZHANG, Lin
Year of Publication 25.04.2024

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Patent

5′-substituted nucleoside compounds

5′-substituted nucleoside compounds

by Cortez Guillermo S, Bonday Zahid Quyoom
Year of Publication 12.12.2017

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Patent

ERK inhibitors

ERK inhibitors

by Zhao, Gaiying, Joseph, Sajan, Rodriguez, Michael John, McMillen, William T, Cortez, Guillermo S, McLean, Johnathan Alexander
Year of Publication 13.07.2021

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Patent

THIENO[2,3-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

THIENO[2,3-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS

by SAJAN JOSEPH, WILLIAM T. MCMILLEN, MICHAEL JOHN RODRIGUEZ, GAIYING ZHAO, JOHNATHAN ALEXANDER MCLEAN, GUILLERMO S. CORTEZ
Year of Publication 13.10.2020

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Patent

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