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Published in Cell (07.03.2019)
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Designed protein logic to target cells with precise combinations of surface antigens
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Published in Science (American Association for the Advancement of Science) (25.09.2020)
Published in Science (American Association for the Advancement of Science) (25.09.2020)
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Accurate de novo design of hyperstable constrained peptides
Bhardwaj, Gaurav, Mulligan, Vikram Khipple, Bahl, Christopher D., Gilmore, Jason M., Harvey, Peta J., Cheneval, Olivier, Buchko, Garry W., Pulavarti, Surya V. S. R. K., Kaas, Quentin, Eletsky, Alexander, Huang, Po-Ssu, Johnsen, William A., Greisen, Per Jr, Rocklin, Gabriel J., Song, Yifan, Linsky, Thomas W., Watkins, Andrew, Rettie, Stephen A., Xu, Xianzhong, Carter, Lauren P., Bonneau, Richard, Olson, James M., Coutsias, Evangelos, Correnti, Colin E., Szyperski, Thomas, Craik, David J., Baker, David
Published in Nature (London) (20.10.2016)
Published in Nature (London) (20.10.2016)
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Proof of principle for epitope-focused vaccine design
Correia, Bruno E., Bates, John T., Loomis, Rebecca J., Baneyx, Gretchen, Carrico, Chris, Jardine, Joseph G., Rupert, Peter, Correnti, Colin, Kalyuzhniy, Oleksandr, Vittal, Vinayak, Connell, Mary J., Stevens, Eric, Schroeter, Alexandria, Chen, Man, MacPherson, Skye, Serra, Andreia M., Adachi, Yumiko, Holmes, Margaret A., Li, Yuxing, Klevit, Rachel E., Graham, Barney S., Wyatt, Richard T., Baker, David, Strong, Roland K., Crowe, James E., Johnson, Philip R., Schief, William R.
Published in Nature (London) (13.03.2014)
Published in Nature (London) (13.03.2014)
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Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
McGuire, Andrew T., Gray, Matthew D., Dosenovic, Pia, Gitlin, Alexander D., Freund, Natalia T., Petersen, John, Correnti, Colin, Johnsen, William, Kegel, Robert, Stuart, Andrew B., Glenn, Jolene, Seaman, Michael S., Schief, William R., Strong, Roland K., Nussenzweig, Michel C., Stamatatos, Leonidas
Published in Nature communications (24.02.2016)
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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways
Pattwell, Siobhan S., Arora, Sonali, Cimino, Patrick J., Ozawa, Tatsuya, Szulzewsky, Frank, Hoellerbauer, Pia, Bonifert, Tobias, Hoffstrom, Benjamin G., Boiani, Norman E., Bolouri, Hamid, Correnti, Colin E., Oldrini, Barbara, Silber, John R., Squatrito, Massimo, Paddison, Patrick J., Holland, Eric C.
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Simultaneous multiple interaction T-cell engaging (SMITE) bispecific antibodies overcome bispecific T-cell engager (BiTE) resistance via CD28 co-stimulation
Correnti, Colin E., Laszlo, George S., de van der Schueren, Willem J., Godwin, Colin D., Bandaranayake, Ashok, Busch, Melanie A., Gudgeon, Chelsea J., Bates, Olivia M., Olson, James M., Mehlin, Christopher, Walter, Roland B.
Published in Leukemia (01.05.2018)
Published in Leukemia (01.05.2018)
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TNIK signaling imprints CD8+ T cell memory formation early after priming
Jaeger-Ruckstuhl, Carla A., Hinterbrandner, Magdalena, Höpner, Sabine, Correnti, Colin E., Lüthi, Ursina, Friedli, Olivier, Freigang, Stefan, Al Sayed, Mohamad F., Bührer, Elias D., Amrein, Michael A., Schürch, Christian M., Radpour, Ramin, Riether, Carsten, Ochsenbein, Adrian F.
Published in Nature communications (02.04.2020)
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Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation
Peng, Tao, Chanthaphavong, R Savanh, Sun, Sijie, Trigilio, James A, Phasouk, Khamsone, Jin, Lei, Layton, Erik D, Li, Alvason Z, Correnti, Colin E, De van der Schueren, Willem, Vazquez, Julio, O'Day, Diana R, Glass, Ian A, Knipe, David M, Wald, Anna, Corey, Lawrence, Zhu, Jia
Published in The Journal of experimental medicine (07.08.2017)
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A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
Cook Sangar, Michelle L, Girard, Emily J, Hopping, Gene, Yin, Chunfeng, Pakiam, Fiona, Brusniak, Mi-Youn, Nguyen, Elizabeth, Ruff, Raymond, Gewe, Mesfin M, Byrnes-Blake, Kelly, Nairn, Natalie W, Miller, Dennis M, Mehlin, Christopher, Strand, Andrew D, Mhyre, Andrew J, Correnti, Colin E, Strong, Roland K, Simon, Julian A, Olson, James M
Published in Science translational medicine (04.03.2020)
Published in Science translational medicine (04.03.2020)
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Engineering and functionalization of large circular tandem repeat protein nanoparticles
Correnti, Colin E., Hallinan, Jazmine P., Doyle, Lindsey A., Ruff, Raymond O., Jaeger-Ruckstuhl, Carla A., Xu, Yuexin, Shen, Betty W., Qu, Amanda, Polkinghorn, Caley, Friend, Della J., Bandaranayake, Ashok D., Riddell, Stanley R., Kaiser, Brett K., Stoddard, Barry L., Bradley, Philip
Published in Nature structural & molecular biology (01.04.2020)
Published in Nature structural & molecular biology (01.04.2020)
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Screening, large-scale production and structure-based classification of cystine-dense peptides
Correnti, Colin E., Gewe, Mesfin M., Mehlin, Christopher, Bandaranayake, Ashok D., Johnsen, William A., Rupert, Peter B., Brusniak, Mi-Youn, Clarke, Midori, Burke, Skyler E., De Van Der Schueren, Willem, Pilat, Kristina, Turnbaugh, Shanon M., May, Damon, Watson, Alex, Chan, Man Kid, Bahl, Christopher D., Olson, James M., Strong, Roland K.
Published in Nature structural & molecular biology (01.03.2018)
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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
Jaeger-Ruckstuhl, Carla A., Lo, Yun, Fulton, Elena, Waltner, Olivia G., Shabaneh, Tamer B., Simon, Sylvain, Muthuraman, Pranav V., Correnti, Colin E., Newsom, Oliver J., Engstrom, Ian A., Kanaan, Sami B., Bhise, Shruti S., Peralta, Jobelle M.C., Ruff, Raymond, Price, Jason P., Stull, Sylvia M., Stevens, Andrew R., Bugos, Grace, Kluesner, Mitchell G., Voillet, Valentin, Muhunthan, Vishaka, Morrish, Fionnuala, Olson, James M., Gottardo, Raphaël, Sarthy, Jay F., Henikoff, Steven, Sullivan, Lucas B., Furlan, Scott N., Riddell, Stanley R.
Published in Immunity (Cambridge, Mass.) (13.02.2024)
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The CD33 splice isoform lacking exon 2 as therapeutic target in human acute myeloid leukemia
Godwin, Colin D., Laszlo, George S., Wood, Brent L., Correnti, Colin E., Bates, Olivia M., Garling, Eliotte E., Mao, Zhengwei J., Beddoe, Mary E., Lunn, Margaret C., Humbert, Olivier, Kiem, Hans-Peter, Walter, Roland B.
Published in Leukemia (01.09.2020)
Published in Leukemia (01.09.2020)
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Targeting the membrane-proximal C2-set domain of CD33 for improved CD33-directed immunotherapy
Godwin, Colin D., Laszlo, George S., Fiorenza, Salvatore, Garling, Eliotte E., Phi, Tinh-Doan, Bates, Olivia M., Correnti, Colin E., Hoffstrom, Benjamin G., Lunn, Margaret C., Humbert, Olivier, Kiem, Hans-Peter, Turtle, Cameron J., Walter, Roland B.
Published in Leukemia (01.09.2021)
Published in Leukemia (01.09.2021)
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Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager
Crook, Zachary R, Girard, Emily J, Sevilla, Gregory P, Brusniak, Mi-Youn, Rupert, Peter B, Friend, Della J, Gewe, Mesfin M, Clarke, Midori, Lin, Ida, Ruff, Raymond, Pakiam, Fiona, Phi, Tinh-Doan, Bandaranayake, Ashok, Correnti, Colin E, Mhyre, Andrew J, Nairn, Natalie W, Strong, Roland K, Olson, James M
Published in Science translational medicine (18.05.2022)
Published in Science translational medicine (18.05.2022)
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Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies
Gopalakrishnapillai, Anilkumar, Correnti, Colin E, Pilat, Kristina, Lin, Ida, Chan, Man Kid, Bandaranayake, Ashok D, Mehlin, Christopher, Kisielewski, Anne, Hamill, Darcy, Kaeding, Allison J, Meshinchi, Soheil, Olson, James M, Kolb, Edward Anders, Barwe, Sonali P
Published in Cancers (26.11.2021)
Published in Cancers (26.11.2021)
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Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
Malhi, Harman, Homad, Leah J., Wan, Yu-Hsin, Poudel, Bibhav, Fiala, Brooke, Borst, Andrew J., Wang, Jing Yang, Walkey, Carl, Price, Jason, Wall, Abigail, Singh, Suruchi, Moodie, Zoe, Carter, Lauren, Handa, Simran, Correnti, Colin E., Stoddard, Barry L., Veesler, David, Pancera, Marie, Olson, James, King, Neil P., McGuire, Andrew T.
Published in Cell reports. Medicine (21.06.2022)
Published in Cell reports. Medicine (21.06.2022)
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