Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics
MacNair, Craig R, Stokes, Jonathan M, Carfrae, Lindsey A, Fiebig-Comyn, Aline A, Coombes, Brian K, Mulvey, Michael R, Brown, Eric D
Published in Nature communications (31.01.2018)
Published in Nature communications (31.01.2018)
Get full text
Journal Article
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy
Ejim, Linda, Farha, Maya A, Falconer, Shannon B, Wildenhain, Jan, Coombes, Brian K, Tyers, Mike, Brown, Eric D, Wright, Gerard D
Published in Nature chemical biology (01.06.2011)
Published in Nature chemical biology (01.06.2011)
Get full text
Journal Article
Evolution of Salmonella -Host Cell Interactions through a Dynamic Bacterial Genome
Ilyas, Bushra, Tsai, Caressa N, Coombes, Brian K
Published in Frontiers in cellular and infection microbiology (29.09.2017)
Published in Frontiers in cellular and infection microbiology (29.09.2017)
Get full text
Journal Article
High-throughput fitness screening and transcriptomics identify a role for a type IV secretion system in the pathogenesis of Crohn's disease-associated Escherichia coli
Elhenawy, Wael, Hordienko, Sarah, Gould, Steven, Oberc, Alexander M, Tsai, Caressa N, Hubbard, Troy P, Waldor, Matthew K, Coombes, Brian K
Published in Nature communications (01.04.2021)
Published in Nature communications (01.04.2021)
Get full text
Journal Article
Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4
Cavallari, Joseph F., Fullerton, Morgan D., Duggan, Brittany M., Foley, Kevin P., Denou, Emmanuel, Smith, Brennan K., Desjardins, Eric M., Henriksbo, Brandyn D., Kim, Kalvin J., Tuinema, Brian R., Stearns, Jennifer C., Prescott, David, Rosenstiel, Philip, Coombes, Brian K., Steinberg, Gregory R., Schertzer, Jonathan D.
Published in Cell metabolism (02.05.2017)
Published in Cell metabolism (02.05.2017)
Get full text
Journal Article
Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2
Caminero, Alberto, McCarville, Justin L, Galipeau, Heather J, Deraison, Celine, Bernier, Steve P, Constante, Marco, Rolland, Corinne, Meisel, Marlies, Murray, Joseph A, Yu, Xuechen B, Alaedini, Armin, Coombes, Brian K, Bercik, Premysl, Southward, Carolyn M, Ruf, Wolfram, Jabri, Bana, Chirdo, Fernando G, Casqueiro, Javier, Surette, Michael G, Vergnolle, Nathalie, Verdu, Elena F
Published in Nature communications (13.03.2019)
Published in Nature communications (13.03.2019)
Get full text
Journal Article
A draft genome of Yersinia pestis from victims of the Black Death
BOS, Kirsten I, SCHUENEMANN, Verena J, WOOD, James, EARN, David J. D, ANN HERRING, D, BAUER, Peter, POINAR, Hendrik N, KRAUSE, Johannes, BRIAN GOLDING, G, BURBANO, Hernán A, WAGLECHNER, Nicholas, COOMBES, Brian K, MCPHEE, Joseph B, DEWITTE, Sharon N, MEYER, Matthias, SCHMEDES, Sarah
Published in Nature (London) (12.10.2011)
Published in Nature (London) (12.10.2011)
Get full text
Journal Article
Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts
Shaler, Christopher R, Parco, Alexandra A, Elhenawy, Wael, Dourka, Jasmeen, Jury, Jennifer, Verdu, Elena F, Coombes, Brian K
Published in Nature communications (18.11.2021)
Published in Nature communications (18.11.2021)
Get full text
Journal Article
A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium
Ellis, Michael J, Tsai, Caressa N, Johnson, Jarrod W, French, Shawn, Elhenawy, Wael, Porwollik, Steffen, Andrews-Polymenis, Helene, McClelland, Michael, Magolan, Jakob, Coombes, Brian K, Brown, Eric D
Published in Nature communications (14.01.2019)
Published in Nature communications (14.01.2019)
Get full text
Journal Article
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance
Stokes, Jonathan M, MacNair, Craig R, Ilyas, Bushra, French, Shawn, Côté, Jean-Philippe, Bouwman, Catrien, Farha, Maya A, Sieron, Arthur O, Whitfield, Chris, Coombes, Brian K, Brown, Eric D
Published in Nature microbiology (06.03.2017)
Published in Nature microbiology (06.03.2017)
Get full text
Journal Article
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death
Schuenemann, Verena J, Bos, Kirsten, DeWitte, Sharon, Schmedes, Sarah, Jamieson, Joslyn, Mittnik, Alissa, Forrest, Stephen, Coombes, Brian K, Wood, James W, Earn, David J. D, White, William, Krause, Johannes, Poinar, Hendrik N
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
Get full text
Journal Article
Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis
Chau, N Y Elizabeth, Ahmad, Shehryar, Whitney, John C, Coombes, Brian K
Published in PLoS pathogens (01.05.2021)
Published in PLoS pathogens (01.05.2021)
Get full text
Journal Article
The transcriptional regulator SsrB is involved in a molecular switch controlling virulence lifestyles of Salmonella
Pérez-Morales, Deyanira, Banda, María M, Chau, N Y Elizabeth, Salgado, Heladia, Martínez-Flores, Irma, Ibarra, J Antonio, Ilyas, Bushra, Coombes, Brian K, Bustamante, Víctor H
Published in PLoS pathogens (01.07.2017)
Published in PLoS pathogens (01.07.2017)
Get full text
Journal Article
General Approach to the Construction of Structure-Switching Reporters from RNA Aptamers
Lau, Pui Sai, Coombes, Brian K, Li, Yingfu
Published in Angewandte Chemie (International ed.) (18.10.2010)
Published in Angewandte Chemie (International ed.) (18.10.2010)
Get full text
Journal Article
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes
Nash, John He, Villegas, Andre, Kropinski, Andrew M, Aguilar-Valenzuela, Renan, Konczy, Paulina, Mascarenhas, Mariola, Ziebell, Kim, Torres, Alfredo G, Karmali, Mohamed A, Coombes, Brian K
Published in BMC genomics (25.11.2010)
Published in BMC genomics (25.11.2010)
Get full text
Journal Article
Molecular Analysis as an Aid To Assess the Public Health Risk of Non-O157 Shiga Toxin-Producing Escherichia coli Strains
Coombes, Brian K, Wickham, Mark E, Mascarenhas, Mariola, Gruenheid, Samantha, Finlay, B. Brett, Karmali, Mohamed A
Published in Applied and Environmental Microbiology (01.04.2008)
Published in Applied and Environmental Microbiology (01.04.2008)
Get full text
Journal Article