Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model
Li, Si-Yang, Converse, Paul J, Betoudji, Fabrice, Lee, Jin, Mdluli, Khisimuzi, Upton, Anna, Fotouhi, Nader, Nuermberger, Eric L
Published in Antimicrobial agents and chemotherapy (18.04.2023)
Published in Antimicrobial agents and chemotherapy (18.04.2023)
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Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis
Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Adamson, John, Converse, Paul J., Swanson, Rosemary V., Almeida, Deepak V., Grosset, Jacques H.
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2015)
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Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis
Yam, Katherine C, D'Angelo, Igor, Kalscheuer, Rainer, Zhu, Haizhong, Wang, Jian-Xin, Snieckus, Victor, Ly, Lan H, Converse, Paul J, Jacobs, Jr, William R, Strynadka, Natalie, Eltis, Lindsay D
Published in PLoS pathogens (01.03.2009)
Published in PLoS pathogens (01.03.2009)
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Characterization of mouse models of Mycobacterium avium complex infection and evaluation of drug combinations
Andréjak, Claire, Almeida, Deepak V, Tyagi, Sandeep, Converse, Paul J, Ammerman, Nicole C, Grosset, Jacques H
Published in Antimicrobial agents and chemotherapy (01.04.2015)
Published in Antimicrobial agents and chemotherapy (01.04.2015)
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Journal Article
Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9
Ordonez, Alvaro A, Tasneen, Rokeya, Pokkali, Supriya, Xu, Ziyue, Converse, Paul J, Klunk, Mariah H, Mollura, Daniel J, Nuermberger, Eric L, Jain, Sanjay K
Published in Disease models & mechanisms (01.07.2016)
Published in Disease models & mechanisms (01.07.2016)
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A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis
Leung-Theung-Long, Stéphane, Coupet, Charles-Antoine, Gouanvic, Marie, Schmitt, Doris, Ray, Aurélie, Hoffmann, Chantal, Schultz, Huguette, Tyagi, Sandeep, Soni, Heena, Converse, Paul J, Arias, Lilibeth, Kleinpeter, Patricia, Sansas, Benoît, Mdluli, Khisimuzi, Vilaplana, Cristina, Cardona, Pere-Joan, Nuermberger, Eric, Marchand, Jean-Baptiste, Silvestre, Nathalie, Inchauspé, Geneviève
Published in PloS one (02.05.2018)
Published in PloS one (02.05.2018)
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Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models
Converse, Paul J, Karakousis, Petros C, Klinkenberg, Lee G, Kesavan, Anup K, Ly, Lan H, Allen, Shannon Sedberry, Grosset, Jacques H, Jain, Sanjay K, Lamichhane, Gyanu, Manabe, Yukari C, McMurray, David N, Nuermberger, Eric L, Bishai, William R
Published in Infection and Immunity (01.03.2009)
Published in Infection and Immunity (01.03.2009)
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Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer
Converse, Paul J, Almeida, Deepak V, Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C, Li, Si-Yang, Anders, Nicole M, Rudek, Michelle A, Grosset, Jacques H, Nuermberger, Eric L
Published in PLoS neglected tropical diseases (01.08.2018)
Published in PLoS neglected tropical diseases (01.08.2018)
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Journal Article
Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease
Converse, Paul J, Tyagi, Sandeep, Xing, Yalan, Li, Si-Yang, Kishi, Yoshito, Adamson, John, Nuermberger, Eric L, Grosset, Jacques H
Published in PLoS neglected tropical diseases (04.06.2015)
Published in PLoS neglected tropical diseases (04.06.2015)
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Understanding the Significance of Biochemistry in the Storage, Handling, Purification, and Sampling of Amphiphilic Mycolactone
Kubicek-Sutherland, Jessica Z, Vu, Dung M, Anderson, Aaron S, Sanchez, Timothy C, Converse, Paul J, Martí-Arbona, Ricardo, Nuermberger, Eric L, Swanson, Basil I, Mukundan, Harshini
Published in Toxins (04.04.2019)
Published in Toxins (04.04.2019)
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Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide
Grosset, Jacques, Almeida, Deepak, Converse, Paul J, Tyagi, Sandeep, Li, Si-Yang, Ammerman, Nicole C, Pym, Alexander S, Wallengren, Kristina, Hafner, Richard, Lalloo, Umesh, Swindells, Susan, Bishai, William R
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
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Journal Article
Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease
Converse, Paul J, Xing, Yalan, Kim, Ki Hyun, Tyagi, Sandeep, Li, Si-Yang, Almeida, Deepak V, Nuermberger, Eric L, Grosset, Jacques H, Kishi, Yoshito
Published in PLoS neglected tropical diseases (01.01.2014)
Published in PLoS neglected tropical diseases (01.01.2014)
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Journal Article
Microbiological, histological, immunological, and toxin response to antibiotic treatment in the mouse model of Mycobacterium ulcerans disease
Sarfo, Fred Stephen, Converse, Paul J, Almeida, Deepak V, Zhang, Jihui, Robinson, Clive, Wansbrough-Jones, Mark, Grosset, Jacques H
Published in PLoS neglected tropical diseases (01.03.2013)
Published in PLoS neglected tropical diseases (01.03.2013)
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Journal Article
BCG-mediated protection against Mycobacterium ulcerans infection in the mouse
Converse, Paul J, Almeida, Deepak V, Nuermberger, Eric L, Grosset, Jacques H
Published in PLoS neglected tropical diseases (15.03.2011)
Published in PLoS neglected tropical diseases (15.03.2011)
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Journal Article
Activities of rifampin, Rifapentine and clarithromycin alone and in combination against mycobacterium ulcerans disease in mice
Almeida, Deepak, Converse, Paul J, Ahmad, Zahoor, Dooley, Kelly E, Nuermberger, Eric L, Grosset, Jacques H
Published in PLoS neglected tropical diseases (04.01.2011)
Published in PLoS neglected tropical diseases (04.01.2011)
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Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set
Sun, Ronggai, Converse, Paul J., Ko, Chiew, Tyagi, Sandeep, Morrison, Norman E., Bishai, William R.
Published in Molecular microbiology (01.04.2004)
Published in Molecular microbiology (01.04.2004)
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Journal Article
Using Bioluminescence To Monitor Treatment Response in Real Time in Mice with Mycobacterium ulcerans Infection
TIANYU ZHANG, LI, Si-Yang, CONVERSE, Paul J, ALMEIDA, Deepak V, GROSSET, Jacques H, NUERMBERGER, Eric L
Published in Antimicrobial Agents and Chemotherapy (01.01.2011)
Published in Antimicrobial Agents and Chemotherapy (01.01.2011)
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Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease
Almeida, Deepak V, Converse, Paul J, Li, Si-Yang, Tyagi, Sandeep, Nuermberger, Eric L, Grosset, Jacques H
Published in PLoS neglected tropical diseases (01.02.2013)
Published in PLoS neglected tropical diseases (01.02.2013)
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