Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase
Ngu, Khehyong, Weinstein, David S., Liu, Wen, Langevine, Charles, Combs, Donald W., Zhuang, Shaobin, Chen, Xing, Madsen, Cort S., Harper, Timothy W., Ahmad, Saleem, Robl, Jeffrey A.
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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Journal Article
Discovery of selective imidazole-based inhibitors of mammalian 15-lipoxygenase: Highly potent against human enzyme within a cellular environment
Weinstein, David S., Liu, Wen, Ngu, Khehyong, Langevine, Charles, Combs, Donald W., Zhuang, Shaobin, Chen, Cindy, Madsen, Cort S., Harper, Timothy W., Robl, Jeffrey A.
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Journal Article
Benzoxazinones as PPARγ Agonists. 2. SAR of the Amide Substituent and In Vivo Results in a Type 2 Diabetes Model
Rybczynski, Philip J, Zeck, Roxanne E, Dudash, Joseph, Combs, Donald W, Burris, Thomas P, Yang, Maria, Osborne, Melville C, Chen, Xiaoli, Demarest, Keith T
Published in Journal of medicinal chemistry (01.01.2004)
Published in Journal of medicinal chemistry (01.01.2004)
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Journal Article
Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase
Weinstein, David S., Liu, Wen, Gu, Zhengxiang, Langevine, Charles, Ngu, Khehyong, Fadnis, Leena, Combs, Donald W., Sitkoff, Doree, Ahmad, Saleem, Zhuang, Shaobin, Chen, Xing, Wang, Feng-Lai, Loughney, Deborah A., Atwal, Karnail S., Zahler, Robert, Macor, John E., Madsen, Cort S., Murugesan, Natesan
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
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Journal Article
PROMOR App: A web application for label-free quantification (LFQ) proteomics data analysis and predictive modeling
Patel, Sagar, Ranathunge, Chathurani, Pinky, Lubna, Nyalwidhe, Julius O., John Semmes, O., Armstrong, Robert K., Donald Combs, C.
Published in 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (06.12.2022)
Published in 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (06.12.2022)
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Conference Proceeding
promor: a comprehensive R package for label-free proteomics data analysis and predictive modeling
Ranathunge, Chathurani, Patel, Sagar S, Pinky, Lubna, Correll, Vanessa L, Chen, Shimin, Semmes, O John, Armstrong, Robert K, Combs, C Donald, Nyalwidhe, Julius O
Published in Bioinformatics advances (01.01.2023)
Published in Bioinformatics advances (01.01.2023)
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Journal Article
Synthesis and evaluation of spirobenzazepines as potent vasopressin receptor antagonists
Xiang, Min Amy, Chen, Robert H., Demarest, Keith T., Gunnet, Joseph, Look, Richard, Hageman, William, Murray, William V., Combs, Donald W., Patel, Mona
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
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Journal Article
Nonsteroidal progesterone receptor ligands. 1. 3-Aryl-1-benzoyl-1,4,5,6- tetrahydropyridazines
Combs, Donald W, Reese, Kimberly, Phillips, Audrey
Published in Journal of medicinal chemistry (01.12.1995)
Published in Journal of medicinal chemistry (01.12.1995)
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Journal Article
Benzoxazinones as PPARγ agonists. part 1: SAR of three aromatic regions
Rybczynski, Philip J., Zeck, Roxanne E., Combs, Donald W., Turchi, Ignatius, Burris, Thomas P., Xu, Jun Z., Yang, Maria, Demarest, Keith T.
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
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Journal Article
Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1
Ahmad, Saleem, Ngu, Khehyong, Combs, Donald W, Wu, Shung C, Weinstein, David S, Liu, Wen, Chen, Bang-Chi, Chandrasena, Gamini, Dorso, Charles R, Kirby, Mark, Atwal, Karnail S
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
Nonsteroidal progesterone receptor ligands with unprecedented receptor selectivity
Palmer, Stephen, Campen, Carolyn A, Allan, George F, Rybczynski, Philip, Haynes-Johnson, Donna, Hutchins, Amy, Kraft, Patricia, Kiddoe, Margaret, Lai, Muh-Tsann, Lombardi, Elizabeth, Pedersen, Phyllis, Hodgen, Gary, Combs, Donald W
Published in The Journal of steroid biochemistry and molecular biology (01.12.2000)
Published in The Journal of steroid biochemistry and molecular biology (01.12.2000)
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Journal Article
Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists
Xiang, Min Amy, Chen, Robert H., Demarest, Keith T., Gunnet, Joseph, Look, Richard, Hageman, William, Murray, William V., Combs, Donald W., Rybczynski, Philip J., Patel, Mona
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
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Journal Article
Nonsteroidal Progesterone Receptor Ligands. 2. High-Affinity Ligands with Selectivity for Bone Cell Progesterone Receptors
Combs, Donald W, Reese, Kimberly, Cornelius, Lyndon A. M, Gunnet, Joseph W, Cryan, Ellen V, Granger, Kay S, Jordan, Jerold J, Demarest, Keith T
Published in Journal of medicinal chemistry (01.12.1995)
Published in Journal of medicinal chemistry (01.12.1995)
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Journal Article
6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents
Combs, Donald W, Rampulla, Marianne S, Bell, Stanley C, Klaubert, Dieter H, Tobia, Alfonso J, Falotico, Robert, Haertlein, Barbara, Lakas-Weiss, Constance, Moore, John B
Published in Journal of medicinal chemistry (01.01.1990)
Published in Journal of medicinal chemistry (01.01.1990)
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Journal Article