PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies
Sen, Malabika, Kindsfather, Audrey, Danilova, Ludmila, Zhang, Feng, Colombo, Raffaele, LaPorte, Matthew G., Kurland, Brenda F., Huryn, Donna M., Wipf, Peter, Herman, James G.
Published in Epigenetics (02.07.2020)
Published in Epigenetics (02.07.2020)
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Journal Article
PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions
Pignataro, Luca, Carboni, Stefano, Civera, Monica, Colombo, Raffaele, Piarulli, Umberto, Gennari, Cesare
Published in Angewandte Chemie (International ed.) (03.09.2010)
Published in Angewandte Chemie (International ed.) (03.09.2010)
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Journal Article
Selective O-acylation of unprotected N-benzylserine methyl ester and O,N-acyl transfer in the formation of cyclo[Asp-Ser] diketopiperazines
Marchini, Mattia, Mingozzi, Michele, Colombo, Raffaele, Gennari, Cesare, Durini, Marco, Piarulli, Umberto
Published in Tetrahedron (04.12.2010)
Published in Tetrahedron (04.12.2010)
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Journal Article
Metabolite-Based Modification of Poly(l‑lysine) for Improved Gene Delivery
Urello, Morgan A, Xiang, Lucia, Colombo, Raffaele, Ma, Alexander, Joseph, Augustine, Boyd, Jonathan, Peterson, Norman, Gao, Changshou, Wu, Herren, Christie, R. James
Published in Biomacromolecules (14.09.2020)
Published in Biomacromolecules (14.09.2020)
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Journal Article
Cyclopentadiene as a Multifunctional Reagent for Normal- and Inverse-Electron Demand Diels–Alder Bioconjugation
Ting, Cheng-Yueh, Kolbeck, Paul T., Colombo, Raffaele, Chakiath, Chacko, Rice, Megan, Marelli, Marcello, Christie, R. James
Published in Bioconjugate chemistry (21.09.2022)
Published in Bioconjugate chemistry (21.09.2022)
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Journal Article
The Journey of Antibody-Drug Conjugates: Lessons Learned from 40 Years of Development
Colombo, Raffaele, Tarantino, Paolo, Rich, Jamie R, LoRusso, Patricia M, de Vries, Elisabeth G E
Published in Cancer discovery (01.11.2024)
Published in Cancer discovery (01.11.2024)
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Journal Article
Abstract 1538: Revisiting the dogma of antibody drug conjugates (ADCs): Emerging data challenge the benefit of linker stability and the primacy of payload delivery
Colombo, Raffaele, Barnscher, Stuart D., Rich, Jamie R.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands
Marchini, Mattia, Mingozzi, Michele, Colombo, Raffaele, Guzzetti, Ileana, Belvisi, Laura, Vasile, Francesca, Potenza, Donatella, Piarulli, Umberto, Arosio, Daniela, Gennari, Cesare
Published in Chemistry : a European journal (14.05.2012)
Published in Chemistry : a European journal (14.05.2012)
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Journal Article
Synthesis and Biological Evaluation (in Vitro and in Vivo) of Cyclic Arginine-Glycine-Aspartate (RGD) Peptidomimetic-Paclitaxel Conjugates Targeting lntegrin alpha(v)beta(3)
Colombo, Raffaele, Mingozzi, Michele, Belvisi, Laura, Arosio, Daniela, Piarulli, Umberto, Carenini, Nives, Perego, Paola, Zaffaroni, Nadia, De Cesare, Michelandrea, Castiglioni, Vittoria, Scanziani, Eugenio, Gennari, Cesare
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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Journal Article
Synthesis and Biological Evaluation (in Vitro and in Vivo) of Cyclic Arginine–Glycine–Aspartate (RGD) Peptidomimetic–Paclitaxel Conjugates Targeting Integrin αVβ3
Colombo, Raffaele, Mingozzi, Michele, Belvisi, Laura, Arosio, Daniela, Piarulli, Umberto, Carenini, Nives, Perego, Paola, Zaffaroni, Nadia, De Cesare, Michelandrea, Castiglioni, Vittoria, Scanziani, Eugenio, Gennari, Cesare
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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Journal Article
Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates
Petersen, Mark E, Brant, Michael G, Lasalle, Manuel, Das, Samir, Duan, Renee, Wong, Jodi, Ding, Tong, Wu, Kaylee J, Siddappa, Dayananda, Fang, Chen, Zhang, Wen, Wu, Alex M L, Hirkala-Schaefer, Truman, Garnett, Graham A E, Fung, Vincent, Yang, Luying, Hernandez Rojas, Andrea, Lawn, Samuel O, Barnscher, Stuart D, Rich, Jamie R, Colombo, Raffaele
Published in Molecular cancer therapeutics (02.05.2024)
Published in Molecular cancer therapeutics (02.05.2024)
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Journal Article
Correction: The first synthesis of N-acetylneuraminic acid 1,7-lactone
Colombo, Raffaele, Anastasia, Mario, Rota, Paola, Allevi, Pietro
Published in Chemical communications (Cambridge, England) (18.03.2015)
Published in Chemical communications (Cambridge, England) (18.03.2015)
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Journal Article
Correction to “Chemoselective Synthesis of Sialic Acid 1,7-Lactones”
Allevi, Pietro, Rota, Paola, Scaringi, Raffaella, Colombo, Raffaele, Anastasia, Mario
Published in Journal of organic chemistry (20.03.2015)
Published in Journal of organic chemistry (20.03.2015)
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Journal Article
Total Synthesis and Biological Evaluation of Tubulysin Analogues
Colombo, Raffaele, Wang, Zhiyong, Han, Junyan, Balachandran, Raghavan, Daghestani, Hikmat N, Camarco, Daniel P, Vogt, Andreas, Day, Billy W, Mendel, David, Wipf, Peter
Published in Journal of organic chemistry (04.11.2016)
Published in Journal of organic chemistry (04.11.2016)
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Journal Article
캄프토테신 유사체, 접합체 및 사용 방법
BARNSCHER STUART DANIEL, PETERSEN MARK EDMUND, DAS SAMIR, RICH JAMES R, COLOMBO RAFFAELE, BRANT MICHAEL G, LASALLE MANUEL MICHEL AUGUSTE
Year of Publication 07.03.2024
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Year of Publication 07.03.2024
Patent
Chemoselective Synthesis of Sialic Acid 1,7-Lactones
Allevi, Pietro, Rota, Paola, Scaringi, Raffaella, Colombo, Raffaele, Anastasia, Mario
Published in Journal of organic chemistry (20.08.2010)
Published in Journal of organic chemistry (20.08.2010)
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Journal Article
Abstract 2641: ZW191, a novel FRa-targeting antibody drug conjugate bearing a topoisomerase 1 inhibitor payload
Lawn, Sam, Rojas, Andrea Hernandez, Colombo, Raffaele, Siddappa, Dayananda, Wong, Jodi, Wu, Kaylee, Fung, Vincent, Urosev, Dunja, Yang, Luying, Rich, Jamie R., Barnscher, Stuart D.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors
LaPorte, Matthew G., Wang, Zhuzhu, Colombo, Raffaele, Garzan, Atefeh, Peshkov, Vsevolod A., Liang, Mary, Johnston, Paul A., Schurdak, Mark E., Sen, Malabika, Camarco, Daniel P., Hua, Yun, Pollock, Netanya I., Lazo, John S., Grandis, Jennifer R., Wipf, Peter, Huryn, Donna M.
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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Journal Article