Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy
Meyers, Marvin J, Arhancet, Graciela B, Hockerman, Susan L, Chen, Xiangyang, Long, Scott A, Mahoney, Matthew W, Rico, Joseph R, Garland, Danny J, Blinn, James. R, Collins, Joe T, Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F, Wendling, Jay M, Dietz, Jessica D, Payne, Maria A, Homer, Bruce L, Heron, Marcia I, Reitz, David B, Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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Stereochemical Requirements for the Mineralocorticoid Receptor Antagonist Activity of Dihydropyridines
Arhancet, Graciela B, Woodard, Scott S, Dietz, Jessica D, Garland, Danny J, Wagner, Grace M, Iyanar, Kaliappan, Collins, Joe T, Blinn, James R, Numann, Randal E, Hu, Xiao, Huang, Horng-Chih
Published in Journal of medicinal chemistry (27.05.2010)
Published in Journal of medicinal chemistry (27.05.2010)
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Process development of a FGF21 protein-antibody conjugate
Dirksen, Anouk, Davis, Keith A, Collins, Joe T, Bhattacharya, Keshab, Finneman, Jari I, Pepin, Erin L, Ryczek, Jeffrey S, Brown, Paul W, Wellborn, William B, Mangalathillam, Ratish, Evans, Brad P, Pozzo, Mark J, Finn, Rory F
Published in Biopolymers (01.01.2018)
Published in Biopolymers (01.01.2018)
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Discovery of Novel Cyanodihydropyridines as Potent Mineralocorticoid Receptor Antagonists
Arhancet, Graciela B, Woodard, Scott S, Iyanar, Kaliappan, Case, Brenda L, Woerndle, Rhonda, Dietz, Jessica D, Garland, Danny J, Collins, Joe T, Payne, Maria A, Blinn, James R, Pomposiello, Silvia I, Hu, Xiao, Heron, Marcia I, Huang, Horng-Chih, Lee, Len F
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents
Li, James J, Anderson, Gary D, Burton, Earl G, Cogburn, J. Nita, Collins, Joe T, Garland, Danny J, Gregory, Susan A, Huang, Horng-Chih, Isakson, Peter C
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
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A Practical Synthesis of [(1S,3S)-3-Aminocyclohexyl]methanol and 2-[(1S,3S)-3-Aminocyclohexyl]propan-2-ol, Useful Intermediates for the Preparation of Novel mPGES-1 Inhibitors
Walker, Daniel P., Heasley, Steven E., MacInnes, Allison, Anjeh, Tizah, Lu, Hwang-Fun, Fobian, Yvette M., Collins, Joe T., Vazquez, Michael L., Mao, Michael K.
Published in Synlett (01.12.2011)
Published in Synlett (01.12.2011)
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R-isomers of Arg-Gly-Asp (RGD) mimics as potent αvβ3 inhibitors
NAGARAJAN, Srinivasan R, DEVADAS, Balekudru, LANTZ, Melissa K, JUN ZHU, GREEN, Nawasa F, RUSSELL, Mark A, LANDIS, Bryan H, MILLER, Lawrence M, MEYER, Debra M, DUFFIN, Tiffany D, ENGLEMAN, V. Wayne, FINN, Mary B, MALECHA, James W, FREEMAN, Sandra K, GRIGGS, David W, WILLIAMS, Melanie L, NICKOLS, Maureen A, PEGG, Jodi A, SHANNON, Kristen E, STEININGER, Christina, WESTLIN, Marisa M, NICKOLS, G. Alan, KEENE, Jeffery L, LU, Hwang-Fun, RUMINSKI, Peter G, RICO, Joseph G, ROGERS, Thomas E, MARRUFO, Laura D, COLLINS, Joe T, KLEINE, H. Peter
Published in Bioorganic & medicinal chemistry (01.06.2007)
Published in Bioorganic & medicinal chemistry (01.06.2007)
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Journal Article
Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy
Meyers, Marvin J., Arhancet, Graciela B., Hockerman, Susan L., Chen, Xiangyang, Long, Scott A., Mahoney, Matthew W., Rico, Joseph R., Garland, Danny J., Blinn, James. R., Collins, Joe T., Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F., Wendling, Jay M., Dietz, Jessica D., Payne, Maria A., Homer, Bruce L., Heron, Marcia I., Reitz, David B., Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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Journal Article
Pilot-Plant Preparation of an αvβ3 Integrin Antagonist. Part 2. Synthesis of N-[2-(5-Hydroxy-4,6-tetrahydropyrimidine)]-3-amino-5-hydroxybenzoic Acid
Clark, Jerry D., Collins, Joe T., Kleine, H. Peter, Weisenburger, Gerald A., Anderson, D. Keith
Published in Organic process research & development (16.07.2004)
Published in Organic process research & development (16.07.2004)
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Journal Article
Pilot-Plant Preparation of an α v β 3 Integrin Antagonist. Part 2. Synthesis of N -[2-(5-Hydroxy-4,6-tetrahydropyrimidine)]-3-amino-5-hydroxybenzoic Acid
Clark, Jerry D., Collins, Joe T., Kleine, H. Peter, Weisenburger, Gerald A., Anderson, D. Keith
Published in Organic process research & development (01.07.2004)
Published in Organic process research & development (01.07.2004)
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Journal Article
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors
Nagarajan, Srinivasan R, Devadas, Balekudru, Malecha, James W, Lu, Hwang-Fun, Ruminski, Peter G, Rico, Joseph G, Rogers, Thomas E, Marrufo, Laura D, Collins, Joe T, Kleine, H Peter, Lantz, Melissa K, Zhu, Jun, Green, Nawasa F, Russell, Mark A, Landis, Bryan H, Miller, Lawrence M, Meyer, Debra M, Duffin, Tiffany D, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Griggs, David W, Williams, Melanie L, Nickols, Maureen A, Pegg, Jodi A, Shannon, Kristen E, Steininger, Christina, Westlin, Marisa M, Nickols, G Alan, Keene, Jeffery L
Published in Bioorganic & medicinal chemistry (01.06.2007)
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Published in Bioorganic & medicinal chemistry (01.06.2007)
Journal Article
R-Isomers of Arg-Gly-Asp (RGD) mimics as potent α vβ 3 inhibitors
Nagarajan, Srinivasan R., Devadas, Balekudru, Malecha, James W., Lu, Hwang-Fun, Ruminski, Peter G., Rico, Joseph G., Rogers, Thomas E., Marrufo, Laura D., Collins, Joe T., Kleine, H. Peter, Lantz, Melissa K., Zhu, Jun, Green, Nawasa F., Russell, Mark A., Landis, Bryan H., Miller, Lawrence M., Meyer, Debra M., Duffin, Tiffany D., Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Griggs, David W., Williams, Melanie L., Nickols, Maureen A., Pegg, Jodi A., Shannon, Kristen E., Steininger, Christina, Westlin, Marisa M., Nickols, G. Alan, Keene, Jeffery L.
Published in Bioorganic & medicinal chemistry (2007)
Published in Bioorganic & medicinal chemistry (2007)
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Journal Article
Selective Cyclooxygenase Inhibitors: Novel 1,2-Diarylcyclopentenes Are Potent and Orally Active COX-2 Inhibitors
Reitz, David B., Li, James J., Norton, Monica B., Reinhard, Emily J., Collins, Joe T., Anderson, Gary D., Gregory, Susan A., Koboldt, Carol M., Perkins, William E.
Published in Journal of medicinal chemistry (01.11.1994)
Published in Journal of medicinal chemistry (01.11.1994)
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Journal Article
N1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists
Reitz, David B., Garland, Danny J., Norton, Monica B., Collins, Joe T., Reinhard, Emily J., Manning, Robert E., Olins, Gillian M., Chen, Susan T., Palomo, Maria A., McMahon, Ellen G., Koehler, Konrad F.
Published in Bioorganic & medicinal chemistry letters (01.06.1993)
Published in Bioorganic & medicinal chemistry letters (01.06.1993)
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Journal Article
N 1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists
Reitz, David B., Garland, Danny J., Norton, Monica B., Collins, Joe T., Reinhard, Emily J., Manning, Robert E., Olins, Gillian M., Chen, Susan T., Palomo, Maria A., McMahon, Ellen G., Koehler, Konrad F.
Published in Bioorganic & medicinal chemistry letters (1993)
Published in Bioorganic & medicinal chemistry letters (1993)
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THE N-BOC GROUP AS AN ACTIVATOR FOR THE ALPHA-LITHIATION OF CARBAMATES - SYNTHESIS OF 11-SUBSTITUTED DIBENZOXAZEPINES
HAGEN, TJ, RAFFERTY, MF, COLLINS, JT, GARLAND, DJ, LI, JJ, NORTON, MB, REITZ, DB, TSYMBALOV, S, PITZELE, BS, HALLINAN, EA
Published in Heterocycles (01.03.1994)
Published in Heterocycles (01.03.1994)
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Journal Article
Anilino liver X-receptor modulators
DECRESCENZO GARY A, VAN CAMP JENNIFER ANN, MALECHA JAMES W, KALMAN MONICA J, MIYASHIRO JULIE M, COLLINS JOE T
Year of Publication 31.05.2005
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Year of Publication 31.05.2005
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