Relationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic Clearance
LIYUE HUANG, BERRY, Loren, GANGA, Sindhura, JANOSKY, Brett, CHEN, April, ROBERTS, Jonathan, COLLETTI, Adria E, JASMINE LIN, Min-Hwa
Published in Drug metabolism and disposition (01.02.2010)
Published in Drug metabolism and disposition (01.02.2010)
Get full text
Journal Article
Deletion of Abcg2 has differential effects on excretion and pharmacokinetics of probe substrates in rats
Huang, Liyue, Be, Xuhai, Tchaparian, Eskouhie H, Colletti, Adria E, Roberts, Jonathan, Langley, Meghan, Ling, Yun, Wong, Bradley K, Jin, Lixia
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
Get full text
Journal Article
Identification of Quinone Imine Containing Glutathione Conjugates of Diclofenac in Rat Bile
Waldon, Daniel J, Teffera, Yohannes, Colletti, Adria E, Liu, Jingzhou, Zurcher, Danielle, Copeland, Katrina W, Zhao, Zhiyang
Published in Chemical research in toxicology (20.12.2010)
Published in Chemical research in toxicology (20.12.2010)
Get full text
Journal Article
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors
Peterson, Emily A., Boezio, Alessandro A., Andrews, Paul S., Boezio, Christiane M., Bush, Tammy L., Cheng, Alan C., Choquette, Deborah, Coats, James R., Colletti, Adria E., Copeland, Katrina W., DuPont, Michelle, Graceffa, Russell, Grubinska, Barbara, Kim, Joseph L., Lewis, Richard T., Liu, Jingzhou, Mullady, Erin L., Potashman, Michele H., Romero, Karina, Shaffer, Paul L., Stanton, Mary K., Stellwagen, John C., Teffera, Yohannes, Yi, Shuyan, Cai, Ti, La, Daniel S.
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Get full text
Journal Article
Bioactivation of Isothiazoles: Minimizing the Risk of Potential Toxicity in Drug Discovery
Teffera, Yohannes, Choquette, Deborah, Liu, Jingzhou, Colletti, Adria E, Hollis, L. Steven, Lin, Min-Hwa Jasmine, Zhao, Zhiyang
Published in Chemical research in toxicology (15.11.2010)
Published in Chemical research in toxicology (15.11.2010)
Get full text
Journal Article
Discovery of triazine-benzimidazoles as selective inhibitors of mTOR
Peterson, Emily A., Andrews, Paul S., Be, Xuhai, Boezio, Alessandro A., Bush, Tammy L., Cheng, Alan C., Coats, James R., Colletti, Adria E., Copeland, Katrina W., DuPont, Michelle, Graceffa, Russell, Grubinska, Barbara, Harmange, Jean-Christophe, Kim, Joseph L., Mullady, Erin L., Olivieri, Philip, Schenkel, Laurie B., Stanton, Mary K., Teffera, Yohannes, Whittington, Douglas A., Cai, Ti, La, Daniel S.
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
Get full text
Journal Article
Chemical Reactivity of Methoxy 4-O-Aryl Quinolines: Identification of Glutathione Displacement Products in Vitro and in Vivo
Teffera, Yohannes, Colletti, Adria E, Harmange, Jean Christophe, Hollis, L. Steven, Albrecht, Brian K, Boezio, Alessandro A, Liu, Jingzhou, Zhao, Zhiyang
Published in Chemical research in toxicology (01.11.2008)
Published in Chemical research in toxicology (01.11.2008)
Get full text
Journal Article
The pharmacokinetics of a thiazole benzenesulfonamide β3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: Improving oral bioavailability
STEARNS, Ralph A, MILLER, Randy R, COLLETTI, Adria E, STRAUSS, John R, KEOHANE, Carol Ann, FEENEY, William P, ILIFF, Susan A, CHIU, Shuet-Hing Lee, WEI TANG, KWEI, Gloria Y, TANG, Frank S, MATHVINK, Robert J, NAYLOR, Elizabeth M, CHITTY, Dawn, COLANDREA, Vincent J, WEBER, Ann E
Published in Drug metabolism and disposition (2002)
Published in Drug metabolism and disposition (2002)
Get full text
Journal Article
Pharmacokinetics and Disposition of the Oxytocin Receptor Antagonist L-368,899 in Rats and Dogs
THOMPSON, K. L, VINCENT, S. H, MILLER, R. R, COLLETTI, A. E, ALVARO, R. F, WALLACE, M. A, FEENEY, W. P, LEE CHIU, S.-H
Published in Drug metabolism and disposition (01.10.1997)
Get full text
Published in Drug metabolism and disposition (01.10.1997)
Journal Article
The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability
Stearns, Ralph A, Miller, Randy R, Tang, Wei, Kwei, Gloria Y, Tang, Frank S, Mathvink, Robert J, Naylor, Elizabeth M, Chitty, Dawn, Colandrea, Vincent J, Weber, Ann E, Colletti, Adria E, Strauss, John R, Keohane, Carol Ann, Feeney, William P, Iliff, Susan A, Chiu, Shuet-Hing Lee
Published in Drug metabolism and disposition (01.07.2002)
Published in Drug metabolism and disposition (01.07.2002)
Get full text
Journal Article
Highly potent, orally active diester macrocyclic human renin inhibitors
Weber, Ann E, Steiner, Mark G, Krieter, Philip A, Colletti, Adria E, Tata, James R, Halgren, Thomas A, Ball, Richard G, Doyle, John J, Schorn, Terry W
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
Get full text
Journal Article
Identification of a novel glutathione conjugate of diclofenac by LTQ-Orbitrap
Teffera, Yohannes, Waldon, Daniel J, Colletti, Adria E, Albrecht, Brian K, Zhao, Zhiyang
Published in Drug metabolism letters (01.01.2008)
Get more information
Published in Drug metabolism letters (01.01.2008)
Journal Article
The Pharmacokinetics of a Thiazole Benzenesulfonamide β3-Adrenergic Receptor Agonist and Its Analogs in Rats, Dogs, and Monkeys: Improving Oral Bioavailability
Ralph A. Stearns, Randy R. Miller, Wei Tang, Gloria Y. Kwei, Frank S. Tang, Robert J. Mathvink, Elizabeth M. Naylor, Dawn Chitty, Vincent J. Colandrea, Ann E. Weber, Adria E. Colletti, John R. Strauss, Carol Ann Keohane, William P. Feeney, Susan A. Iliff, Shuet-Hing Lee Chiu
Published in Drug metabolism and disposition (01.07.2002)
Published in Drug metabolism and disposition (01.07.2002)
Get full text
Journal Article
Orally active inhibitors of human leukocyte elastase. I. Disposition of L-683,845 in rats and rhesus monkeys
Vincent, S H, Painter, S K, Krieter, P A, Colletti, A E, Lyszack, E, Rosegay, A, Dean, D, Luffer-Atlas, D, Miller, R R, Cioffe, C, Chiu, S H
Published in Drug metabolism and disposition (01.12.1996)
Get more information
Published in Drug metabolism and disposition (01.12.1996)
Journal Article
Nitric oxide inhibition causes an exaggerated pressor response in Yucatan miniature swine
Vogl, H.W, Colletti, A.E, Zambraski, E.J
Published in Laboratory animal science (Chicago) (01.04.1997)
Get full text
Published in Laboratory animal science (Chicago) (01.04.1997)
Journal Article