LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics
Nguyen, Holly M., Vessella, Robert L., Morrissey, Colm, Brown, Lisha G., Coleman, Ilsa M., Higano, Celestia S., Mostaghel, Elahe A., Zhang, Xiaotun, True, Lawrence D., Lam, Hung‐Ming, Roudier, Martine, Lange, Paul H., Nelson, Peter S., Corey, Eva
Published in The Prostate (01.05.2017)
Published in The Prostate (01.05.2017)
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Journal Article
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling
Brady, Lauren, Kriner, Michelle, Coleman, Ilsa, Morrissey, Colm, Roudier, Martine, True, Lawrence D., Gulati, Roman, Plymate, Stephen R., Zhou, Zoey, Birditt, Brian, Meredith, Rhonda, Geiss, Gary, Hoang, Margaret, Beechem, Joseph, Nelson, Peter S.
Published in Nature communications (03.03.2021)
Published in Nature communications (03.03.2021)
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Journal Article
Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling
Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.
Published in Cancer cell (09.10.2017)
Published in Cancer cell (09.10.2017)
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Journal Article
Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer
Labrecque, Mark P, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lakely, Bryce, Nguyen, Holly M, Yang, Yu C, da Costa, Rui M Gil, Kaipainen, Arja, Coleman, Roger, Higano, Celestia S, Yu, Evan Y, Cheng, Heather H, Mostaghel, Elahe A, Montgomery, Bruce, Schweizer, Michael T, Hsieh, Andrew C, Lin, Daniel W, Corey, Eva, Nelson, Peter S, Morrissey, Colm
Published in The Journal of clinical investigation (01.10.2019)
Published in The Journal of clinical investigation (01.10.2019)
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Journal Article
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
Carlson, Patrick, Dasgupta, Arko, Grzelak, Candice A., Kim, Jeanna, Barrett, Alexander, Coleman, Ilsa M., Shor, Ryann E., Goddard, Erica T., Dai, Jinxiang, Schweitzer, Emma M., Lim, Andrea R., Crist, Sarah B., Cheresh, David A., Nelson, Peter S., Hansen, Kirk C., Ghajar, Cyrus M.
Published in Nature cell biology (01.02.2019)
Published in Nature cell biology (01.02.2019)
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Journal Article
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
Sun, Yu, Campisi, Judith, Higano, Celestia, Beer, Tomasz M, Porter, Peggy, Coleman, Ilsa, True, Lawrence, Nelson, Peter S
Published in Nature medicine (01.09.2012)
Published in Nature medicine (01.09.2012)
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Journal Article
Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress
Nyquist, Michael D., Corella, Alexandra, Coleman, Ilsa, De Sarkar, Navonil, Kaipainen, Arja, Ha, Gavin, Gulati, Roman, Ang, Lisa, Chatterjee, Payel, Lucas, Jared, Pritchard, Colin, Risbridger, Gail, Isaacs, John, Montgomery, Bruce, Morrissey, Colm, Corey, Eva, Nelson, Peter S.
Published in Cell reports (Cambridge) (26.05.2020)
Published in Cell reports (Cambridge) (26.05.2020)
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Journal Article
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
Sun, Shihua, Sprenger, Cynthia C T, Vessella, Robert L, Haugk, Kathleen, Soriano, Kathryn, Mostaghel, Elahe A, Page, Stephanie T, Coleman, Ilsa M, Nguyen, Holly M, Sun, Huiying, Nelson, Peter S, Plymate, Stephen R
Published in The Journal of clinical investigation (01.08.2010)
Published in The Journal of clinical investigation (01.08.2010)
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Journal Article
SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer
Zhang, Xiaotun, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lucas, Jared M, Lam, Hung-Ming, Dumpit, Ruth, Corey, Eva, Chéry, Lisly, Lakely, Bryce, Higano, Celestia S, Montgomery, Bruce, Roudier, Martine, Lange, Paul H, Nelson, Peter S, Vessella, Robert L, Morrissey, Colm
Published in Clinical cancer research (15.10.2015)
Published in Clinical cancer research (15.10.2015)
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Journal Article
Imaging Fibroblast Activation Protein Alpha Improves Diagnosis of Metastatic Prostate Cancer with Positron Emission Tomography
Hintz, Hallie M, Gallant, Joseph P, Vander Griend, Donald J, Coleman, Ilsa M, Nelson, Peter S, LeBeau, Aaron M
Published in Clinical cancer research (15.09.2020)
Published in Clinical cancer research (15.09.2020)
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Journal Article
Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer
Glumac, Paige M, Gallant, Joseph P, Shapovalova, Mariya, Li, Yingming, Murugan, Paari, Gupta, Shilpa, Coleman, Ilsa M, Nelson, Peter S, Dehm, Scott M, LeBeau, Aaron M
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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Journal Article
Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature
Labrecque, Mark P, Brown, Lisha G, Coleman, Ilsa M, Nguyen, Holly M, Lin, Daniel W, Corey, Eva, Nelson, Peter S, Morrissey, Colm
Published in PloS one (20.01.2021)
Published in PloS one (20.01.2021)
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Journal Article
Therapeutic Implications for Intrinsic Phenotype Classification of Metastatic Castration-Resistant Prostate Cancer
Coleman, Ilsa M, DeSarkar, Navonil, Morrissey, Colm, Xin, Li, Roudier, Martine P, Sayar, Erolcan, Li, Dapei, Corey, Eva, Haffner, Michael C, Nelson, Peter S
Published in Clinical cancer research (15.07.2022)
Published in Clinical cancer research (15.07.2022)
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Journal Article
Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer
Lim, Yiting, Arora, Sonali, Schuster, Samantha L., Corey, Lukas, Fitzgibbon, Matthew, Wladyka, Cynthia L., Wu, Xiaoying, Coleman, Ilsa M., Delrow, Jeffrey J., Corey, Eva, True, Lawrence D., Nelson, Peter S., Ha, Gavin, Hsieh, Andrew C.
Published in Nature communications (09.07.2021)
Published in Nature communications (09.07.2021)
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Journal Article
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
Lucas, Jared M, Heinlein, Cynthia, Kim, Tom, Hernandez, Susana A, Malik, Muzdah S, True, Lawrence D, Morrissey, Colm, Corey, Eva, Montgomery, Bruce, Mostaghel, Elahe, Clegg, Nigel, Coleman, Ilsa, Brown, Christopher M, Schneider, Eric L, Craik, Charles, Simon, Julian A, Bedalov, Antonio, Nelson, Peter S
Published in Cancer discovery (01.11.2014)
Published in Cancer discovery (01.11.2014)
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Journal Article
Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
Cai, Changmeng, He, Housheng Hansen, Chen, Sen, Coleman, Ilsa, Wang, Hongyun, Fang, Zi, Chen, Shaoyong, Nelson, Peter S., Liu, X. Shirley, Brown, Myles, Balk, Steven P.
Published in Cancer cell (18.10.2011)
Published in Cancer cell (18.10.2011)
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Journal Article
Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate
Pascal, Laura E, True, Lawrence D, Campbell, David S, Deutsch, Eric W, Risk, Michael, Coleman, Ilsa M, Eichner, Lillian J, Nelson, Peter S, Liu, Alvin Y
Published in BMC genomics (23.05.2008)
Published in BMC genomics (23.05.2008)
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Journal Article
The effects of aging on the molecular and cellular composition of the prostate microenvironment
Bianchi-Frias, Daniella, Vakar-Lopez, Funda, Coleman, Ilsa M, Plymate, Stephen R, Reed, May J, Nelson, Peter S
Published in PloS one (01.09.2010)
Published in PloS one (01.09.2010)
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Journal Article
Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer
Pritchard, Colin C., Morrissey, Colm, Kumar, Akash, Zhang, Xiaotun, Smith, Christina, Coleman, Ilsa, Salipante, Stephen J., Milbank, Jennifer, Yu, Ming, Grady, William M., Tait, Jonathan F., Corey, Eva, Vessella, Robert L., Walsh, Tom, Shendure, Jay, Nelson, Peter S.
Published in Nature communications (25.09.2014)
Published in Nature communications (25.09.2014)
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