Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan : a quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)
MURPHY, G, COCKETT, M. I, WARD, R. V, DOCHERTY, A. J. P
Published in Biochemical journal (01.07.1991)
Published in Biochemical journal (01.07.1991)
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The role of the C-terminal domain in collagenase and stromelysin specificity
MURPHY, G, ALLAN, J. A, WILLENBROCK, F, COCKETT, M. I, O'CONNEL, J. P, DOCHERTY, A. J. P
Published in The Journal of biological chemistry (15.05.1992)
Published in The Journal of biological chemistry (15.05.1992)
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Assessment of the role of the fibronectin-like domain of gelatinase A by analysis of a deletion mutant
MURPHY, G, QUANG NGUYEN, COCKETT, M. I, ATKINSON, S. J, ALLAN, J. A, KNIGHT, C. G, WILLENBROCK, F, DOCHERTY, A. J. P
Published in The Journal of biological chemistry (04.03.1994)
Published in The Journal of biological chemistry (04.03.1994)
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Journal Article
RGS7 Is Palmitoylated and Exists as Biochemically Distinct Forms
Rose, Jeremy J., Taylor, Jackie B., Shi, Jing, Cockett, Mark I., Jones, Philip G., Hepler, John R.
Published in Journal of neurochemistry (01.11.2000)
Published in Journal of neurochemistry (01.11.2000)
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Antisense Oligonucleotide‐Induced Reduction in 5‐Hydroxytryptamine7 Receptors in the Rat Hypothalamus Without Alteration in Exploratory Behaviour or Neuroendocrine Function
Clemett, D. A., Cockett, M. I., Marsden, C. A., Fone, K. C. F.
Published in Journal of neurochemistry (01.09.1998)
Published in Journal of neurochemistry (01.09.1998)
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Journal Article
The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases
Murphy, G, Willenbrock, F, Ward, R V, Cockett, M I, Eaton, D, Docherty, A J
Published in Biochemical journal (01.05.1992)
Published in Biochemical journal (01.05.1992)
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The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A
Willenbrock, Frances, Crabbe, Thomas, Slocombe, Patrick M, Sutton, Chris W, Docherty, Andrew J. P, Cockett, Mark I, O'Shea, Mark, Brocklehurst, Keith, Phillips, Ian R, Murphy, Gillian
Published in Biochemistry (Easton) (27.04.1993)
Published in Biochemistry (Easton) (27.04.1993)
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The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity
Murphy, Gillian, Houbrechts, Annick, Cockett, Mark I, Williamson, Richard A, O'Shea, Mark, Docherty, Andrew J. P
Published in Biochemistry (Easton) (01.08.1991)
Published in Biochemistry (Easton) (01.08.1991)
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Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes
Murphy, G, Cockett, M I, Stephens, P E, Smith, B J, Docherty, A J
Published in Biochemical journal (15.11.1987)
Published in Biochemical journal (15.11.1987)
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Different Domain Interactions Are Involved in the Binding of Tissue Inhibitors of Metalloproteinases to Stromelysin-1 and Gelatinase A
Nguyen, Quang, Willenbrock, Frances, Cockett, Mark I, O'Shea, Mark, Docherty, Andrew J. P, Murphy, Gillian
Published in Biochemistry (Easton) (01.03.1994)
Published in Biochemistry (Easton) (01.03.1994)
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Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13
O'Shea, Mark, Willenbrock, Frances, Williamson, Richard A, Cockett, Mark I, Freedman, Robert B, Reynolds, John J, Docherty, Andrew J. P, Murphy, Gillian
Published in Biochemistry (Easton) (27.10.1992)
Published in Biochemistry (Easton) (27.10.1992)
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Metalloproteinase domain structure, cellular invasion and metastasis
Cockett, M I, Birch, M L, Murphy, G, Hart, I R, Docherty, A J
Published in Biochemical Society transactions (01.02.1994)
Published in Biochemical Society transactions (01.02.1994)
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Selective Uncoupling of RGS Action by a Single Point Mutation in the G Protein α-Subunit
DiBello, Paul R., Garrison, Tiffany Runyan, Apanovitch, Donald M., Hoffman, Ginger, Shuey, David J., Mason, Kimberly, Cockett, Mark I., Dohlman, Henrik G.
Published in The Journal of biological chemistry (06.03.1998)
Published in The Journal of biological chemistry (06.03.1998)
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Crystallization and preliminary X-ray analysis of nonglycosylated tissue inhibitor of metalloproteinases-1, N30QN78Q TIMP-1
Tolley, S P, Davies, G J, O'Shea, M, Cockett, M I, Docherty, A J, Murphy, G
Published in Proteins, structure, function, and bioinformatics (01.12.1993)
Published in Proteins, structure, function, and bioinformatics (01.12.1993)
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New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans
Mewshaw, Richard E, Kavanagh, Joseph, Stack, Gary, Marquis, Karen L, Shi, Xiaojie, Kagan, Michael Z, Webb, Michael B, Katz, Alan H, Park, Anna, Kang, Young H, Abou-Gharbia, Magid, Scerni, Rosemary, Wasik, Theodore, Cortes-Burgos, Luz, Spangler, Taylor, Brennan, Julie A, Piesla, Michael, Mazandarani, Hossein, Cockett, Mark I, Ochalski, Rafal, Coupet, Joseph, Andree, Terrance H
Published in Journal of medicinal chemistry (19.12.1997)
Published in Journal of medicinal chemistry (19.12.1997)
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RGS7 attenuates signal transduction through the G(alpha q) family of heterotrimeric G proteins in mammalian cells
Shuey, D J, Betty, M, Jones, P G, Khawaja, X Z, Cockett, M I
Published in Journal of neurochemistry (01.05.1998)
Published in Journal of neurochemistry (01.05.1998)
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