Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs
Pradere, Ugo, Garnier-Amblard, Ethel C, Coats, Steven J, Amblard, Franck, Schinazi, Raymond F
Published in Chemical reviews (24.09.2014)
Published in Chemical reviews (24.09.2014)
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Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs
Sari, Ozkan, Bassit, Leda, Gavegnano, Christina, McBrayer, Tamara R., McCormick, Louise, Cox, Bryan, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.
Published in Tetrahedron letters (15.02.2017)
Published in Tetrahedron letters (15.02.2017)
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Efficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection
Cho, Jong Hyun, Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.
Published in Tetrahedron (29.07.2011)
Published in Tetrahedron (29.07.2011)
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Diastereoselective Synthesis of 2′-Dihalopyrimidine Ribonucleoside Inhibitors of Hepatitis C Virus Replication
Zhou, Longhu, Zhang, Hongwang, Li, Chengwei, De Schutter, Coralie, Sari, Ozkan, Mengshetti, Seema, Zhou, Shaoman, Kasthuri, Mahesh, Coats, Steven J, Schinazi, Raymond F, Amblard, Franck
Published in ACS omega (11.01.2022)
Published in ACS omega (11.01.2022)
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Trimethylsilyl-Directed 1,3-Dipolar Cycloaddition Reactions in the Solid-Phase Synthesis of 1,2,3-Triazoles
Coats, Steven J, Link, Jeffrey S, Gauthier, Diane, Hlasta, Dennis J
Published in Organic letters (14.04.2005)
Published in Organic letters (14.04.2005)
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Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors
Zhou, Longhu, Amblard, Franck, Zhang, Hongwang, McBrayer, Tamara R., Detorio, Mervi A., Whitaker, Tony, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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HIV nucleoside reverse transcriptase inhibitors
Amblard, Franck, Patel, Dharmeshkumar, Michailidis, Eleftherios, Coats, Steven J., Kasthuri, Mahesh, Biteau, Nicolas, Tber, Zahira, Ehteshami, Maryam, Schinazi, Raymond F.
Published in European journal of medicinal chemistry (05.10.2022)
Published in European journal of medicinal chemistry (05.10.2022)
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Anti-Human Immunodeficiency Virus Activity, Cross-Resistance, Cytotoxicity, and Intracellular Pharmacology of the 3′-Azido-2′,3′-Dideoxypurine Nucleosides
SLUIS-CREMER, Nicolas, KOONTZ, Dianna, SCHINAZI, Raymond F, MELLORS, John W, BASSIT, Leda, HERNANDEZ-SANTIAGO, Brenda I, DETORIO, Mervi, RAPP, Kim L, AMBLARD, Franck, BONDADA, Lavanya, GRIER, Jason, COATS, Steven J
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
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The Base Component of 3′-Azido-2′,3′-Dideoxynucleosides Influences Resistance Mutations Selected in HIV-1 Reverse Transcriptase
METEER, Jeffrey D, KOONTZ, Dianna, ASIF, Ghazia, ZHANG, Hong-Wang, DETORIO, Mervi, SOLOMON, Sarah, COATS, Steven J, SLUIS-CREMER, Nicolas, SCHINAZI, Raymond F, MELLORS, John W
Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
Published in Antimicrobial Agents and Chemotherapy (01.08.2011)
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Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors
Boucle, Sebastien, Lu, Xiao, Bassit, Leda, Ozturk, Tugba, Russell, Olivia Ollinger, Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
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Synthesis and anti-HCV activity of β-d-2′-deoxy-2′-α-chloro-2′-β-fluoro and β-d-2′-deoxy-2′-α-bromo-2′-β-fluoro nucleosides and their phosphoramidate prodrugs
Ovadia, Reuben, Khalil, Ahmed, Li, Hao, De Schutter, Coralie, Mengshetti, Seema, Zhou, Shaoman, Bassit, Leda, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry (15.02.2019)
Published in Bioorganic & medicinal chemistry (15.02.2019)
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2′-Chloro,2′-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture
Zhou, Shaoman, Mahmoud, Sawsan, Liu, Peng, Zhou, Longhu, Ehteshami, Maryam, Bassit, Leda, Tao, Sijia, Domaoal, Robert A, Sari, Ozkan, Schutter, Coralie De, Amiralaei, Sheida, Khalil, Ahmed, Ollinger Russell, Olivia, McBrayer, Tamara, Whitaker, Tony, Abou-Taleb, Nageh, Amblard, Franck, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
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Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases
Cho, Jong hyun, Coats, Steven J., Schinazi, Raymond F.
Published in Tetrahedron letters (03.06.2015)
Published in Tetrahedron letters (03.06.2015)
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Asymmetric Binding to NS5A by Daclatasvir (BMS-790052) and Analogs Suggests Two Novel Modes of HCV Inhibition
Nettles, James H, Stanton, Richard A, Broyde, Joshua, Amblard, Franck, Zhang, Hongwang, Zhou, Longhu, Shi, Junxing, McBrayer, Tamara R, Whitaker, Tony, Coats, Steven J, Kohler, James J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (11.12.2014)
Published in Journal of medicinal chemistry (11.12.2014)
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Synthesis and anti-HCV activity of a series of β-d-2′-deoxy-2′-dibromo nucleosides and their corresponding phosphoramidate prodrugs
Chen, Zhe, Cox, Bryan D., Garnier-Amblard, Ethel C., McBrayer, Tamara R., Coats, Steven J., Schinazi, Raymond F., Amblard, Franck
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Journal Article
Discovery of a Series of 2′-α-Fluoro,2′-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus
Mengshetti, Seema, Zhou, Longhu, Sari, Ozkan, De Schutter, Coralie, Zhang, Hongwang, Cho, Jong Hyun, Tao, Sijia, Bassit, Leda C, Verma, Kiran, Domaoal, Robert A, Ehteshami, Maryam, Jiang, Yong, Ovadia, Reuben, Kasthuri, Mahesh, Ollinger Russell, Olivia, McBrayer, Tamara, Whitaker, Tony, Pattassery, Judy, Pascual, Maria Luz, Uher, Lothar, Lin, Biing Y, Lee, Sam, Amblard, Franck, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
β‑d‑2′‑C‑Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms
Zhou, Longhu, Zhang, Hong-wang, Tao, Sijia, Bassit, Leda, Whitaker, Tony, McBrayer, Tamara R, Ehteshami, Maryam, Amiralaei, Sheida, Pradere, Ugo, Cho, Jong Hyun, Amblard, Franck, Bobeck, Drew, Detorio, Mervi, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (23.04.2015)
Published in Journal of medicinal chemistry (23.04.2015)
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