Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease
Vancamelbeke, Maaike, Vanuytsel, Tim, Farré, Ricard, Verstockt, Sare, Ferrante, Marc, Van Assche, Gert, Rutgeerts, Paul, Schuit, Frans, Vermeire, Séverine, Arijs, Ingrid, Cleynen, Isabelle
Published in Inflammatory bowel diseases (01.10.2017)
Published in Inflammatory bowel diseases (01.10.2017)
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Journal Article
Cellular diversity in the colon: another brick in the wall
Cleynen, Isabelle, Laukens, Debby
Published in Nature reviews. Gastroenterology & hepatology (01.07.2019)
Published in Nature reviews. Gastroenterology & hepatology (01.07.2019)
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Journal Article
A Genetic Variation in the Neonatal Fc-Receptor Affects Anti-TNF Drug Concentrations in Inflammatory Bowel Disease
Billiet, Thomas, Dreesen, Erwin, Cleynen, Isabelle, Wollants, Willem-Jan, Ferrante, Marc, Van Assche, Gert, Gils, Ann, Vermeire, Severine
Published in The American journal of gastroenterology (01.10.2016)
Published in The American journal of gastroenterology (01.10.2016)
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Journal Article
Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project
Cleynen, Isabelle, González, Juan R, Figueroa, Carolina, Franke, Andre, McGovern, Dermot, Bortlík, Martin, Crusius, Bart J A, Vecchi, Maurizio, Artieda, Marta, Szczypiorska, Magdalena, Bethge, Johannes, Arteta, David, Ayala, Edgar, Danese, Silvio, van Hogezand, Ruud A, Panés, Julian, Peña, Salvador Amado, Lukas, Milan, Jewell, Derek P, Schreiber, Stefan, Vermeire, Severine, Sans, Miquel
Published in Gut (01.11.2013)
Published in Gut (01.11.2013)
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Journal Article
Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease
Henckaerts, Liesbet, Cleynen, Isabelle, Brinar, Marko, John, Jestinah Mahachie, Van Steen, Kristel, Rutgeerts, Paul, Vermeire, Séverine
Published in Inflammatory bowel diseases (01.06.2011)
Published in Inflammatory bowel diseases (01.06.2011)
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Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment
Arijs, Ingrid, De Hertogh, Gert, Lemaire, Katleen, Quintens, Roel, Van Lommel, Leentje, Van Steen, Kristel, Leemans, Peter, Cleynen, Isabelle, Van Assche, Gert, Vermeire, Séverine, Geboes, Karel, Schuit, Frans, Rutgeerts, Paul
Published in PloS one (24.11.2009)
Published in PloS one (24.11.2009)
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Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
Cleynen, Isabelle, Vazeille, Emilie, Artieda, Marta, Verspaget, Hein W, Szczypiorska, Magdalena, Bringer, Marie-Agnès, Lakatos, Peter L, Seibold, Frank, Parnell, Kirstie, Weersma, Rinse K, Mahachie John, Jestinah M, Morgan-Walsh, Rebecca, Staelens, Dominiek, Arijs, Ingrid, De Hertogh, Gert, Müller, Stefan, Tordai, Atilla, Hommes, Daniel W, Ahmad, Tariq, Wijmenga, Cisca, Pender, Sylvia, Rutgeerts, Paul, Van Steen, Kristel, Lottaz, Daniel, Vermeire, Severine, Darfeuille-Michaud, Arlette
Published in Gut (01.08.2014)
Published in Gut (01.08.2014)
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Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
Hong, Shengjun, Prokopenko, Dmitry, Dobricic, Valerija, Kilpert, Fabian, Bos, Isabelle, Vos, Stephanie J. B., Tijms, Betty M., Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Cleynen, Isabelle, Gabel, Silvy, Schaeverbeke, Jolien, Scheltens, Philip, Teunissen, Charlotte E., Niemantsverdriet, Ellis, Engelborghs, Sebastiaan, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C., Bordet, Regis, Molinuevo, José Luis, Rami, Lorena, Kettunen, Petronella, Wallin, Anders, Lleó, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J. B., Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Wittig, Michael, Franke, Andre, Tanzi, Rudolph E., Visser, Pieter Jelle, Bertram, Lars
Published in Translational psychiatry (22.11.2020)
Published in Translational psychiatry (22.11.2020)
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Association of Alzheimer's disease polygenic risk scores with amyloid accumulation in cognitively intact older adults
Luckett, Emma S, Abakkouy, Yasmina, Reinartz, Mariska, Adamczuk, Katarzyna, Schaeverbeke, Jolien, Verstockt, Sare, De Meyer, Steffi, Van Laere, Koen, Dupont, Patrick, Cleynen, Isabelle, Vandenberghe, Rik
Published in Alzheimer's research & therapy (23.09.2022)
Published in Alzheimer's research & therapy (23.09.2022)
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Journal Article
Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults
Luckett, Emma S, Zielonka, Magdalena, Kordjani, Amine, Schaeverbeke, Jolien, Adamczuk, Katarzyna, De Meyer, Steffi, Van Laere, Koen, Dupont, Patrick, Cleynen, Isabelle, Vandenberghe, Rik
Published in Alzheimer's research & therapy (12.07.2023)
Published in Alzheimer's research & therapy (12.07.2023)
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Journal Article
A Matrix-based Model Predicts Primary Response to Infliximab in Crohn’s Disease
Billiet, Thomas, Papamichael, Konstantinos, de Bruyn, Magali, Verstockt, Bram, Cleynen, Isabelle, Princen, Fred, Singh, Sharat, Ferrante, Marc, Van Assche, Gert, Vermeire, Severine
Published in Journal of Crohn's and colitis (01.12.2015)
Published in Journal of Crohn's and colitis (01.12.2015)
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Journal Article
Confirmation of Multiple Crohn's Disease Susceptibility Loci in a Large Dutch-Belgian Cohort
WEERSMA, Rinse K, STOKKERS, Pieter C. F, WIJMENGA, Cisca, VERMEIRE, Séverine, CLEYNEN, Isabelle, WOLFKAMP, Simone C. S, HENCKAERTS, Liesbet, SCHREIBER, Stefan, DIJKSTRA, Gerard, FRANKE, Andre, NOLTE, Ilja M, RUTGEERTS, Paul
Published in The American journal of gastroenterology (01.03.2009)
Published in The American journal of gastroenterology (01.03.2009)
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Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis
Pereira, Márcia S, Durães, Cecília, Catarino, Telmo A, Costa, José L, Cleynen, Isabelle, Novokmet, Mislav, Krištić, Jasminka, Štambuk, Jerko, Conceição-Neto, Nádia, Machado, José C, Marcos-Pinto, Ricardo, Magro, Fernando, Vermeire, Séverine, Lauc, Gordan, Lago, Paula, Pinho, Salomé S
Published in Clinical and translational gastroenterology (01.04.2020)
Published in Clinical and translational gastroenterology (01.04.2020)
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Journal Article
Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau‐PET load in cognitively intact older adults
Schaeverbeke, Jolien, Luckett, Emma S, Gabel, Silvy, Reinartz, Mariska, De Meyer, Steffi, Cleynen, Isabelle, Sleegers, Kristel, Van Broeckhoven, Christine, Bormans, Guy, Serdons, Kim, Van Laere, Koen, Dupont, Patrick, Vandenberghe, Rik
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)
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Journal Article
An efficient algorithm to perform multiple testing in epistasis screening
Van Lishout, François, Mahachie John, Jestinah M, Gusareva, Elena S, Urrea, Victor, Cleynen, Isabelle, Théâtre, Emilie, Charloteaux, Benoît, Calle, Malu Luz, Wehenkel, Louis, Van Steen, Kristel
Published in BMC bioinformatics (24.04.2013)
Published in BMC bioinformatics (24.04.2013)
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Molecular Changes in the Non-Inflamed Terminal Ileum of Patients with Ulcerative Colitis
Lee, Ho-Su, Vancamelbeke, Maaike, Verstockt, Sare, Wilms, Tom, Verstockt, Bram, Sabino, João, Ferrante, Marc, Vermeire, Séverine, Cleynen, Isabelle
Published in Cells (Basel, Switzerland) (28.07.2020)
Published in Cells (Basel, Switzerland) (28.07.2020)
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Journal Article
Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review
Cleynen, Isabelle, Jüni, Peter, Bekkering, Geertruida E, Nüesch, Eveline, Mendes, Camila T, Schmied, Stefanie, Wyder, Stefan, Kellen, Eliane, Villiger, Peter M, Rutgeerts, Paul, Vermeire, Séverine, Lottaz, Daniel
Published in PloS one (08.09.2011)
Published in PloS one (08.09.2011)
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ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior
Forni, Diego, Cleynen, Isabelle, Ferrante, Marc, Cassinotti, Andrea, Cagliani, Rachele, Ardizzone, Sandro, Vermeire, Severine, Fichera, Maria, Lombardini, Marta, Maconi, Giovanni, de Franchis, Roberto, Asselta, Rosanna, Biasin, Mara, Clerici, Mario, Sironi, Manuela
Published in Journal of Crohn's and colitis (01.06.2014)
Published in Journal of Crohn's and colitis (01.06.2014)
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