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Published in eLife (11.09.2024)
Published in eLife (11.09.2024)
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Preclinical Strategy to Reduce Clinical Hepatotoxicity Using in Vitro Bioactivation Data for >200 Compounds
Sakatis, Melanie Z, Reese, Melinda J, Harrell, Andrew W, Taylor, Maxine A, Baines, Ian A, Chen, Liangfu, Bloomer, Jackie C, Yang, Eric Y, Ellens, Harma M, Ambroso, Jeffrey L, Lovatt, Cerys A, Ayrton, Andrew D, Clarke, Stephen E
Published in Chemical research in toxicology (15.10.2012)
Published in Chemical research in toxicology (15.10.2012)
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Sulfamethoxazole and Its Metabolite Nitroso Sulfamethoxazole Stimulate Dendritic Cell Costimulatory Signaling
Sanderson, Joseph P, Naisbitt, Dean J, Farrell, John, Ashby, Charlotte A, Tucker, M. Jane, Rieder, Michael J, Pirmohamed, Munir, Clarke, Stephen E, Park, B. Kevin
Published in Journal of Immunology (01.05.2007)
Published in Journal of Immunology (01.05.2007)
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Contrast coding in the electrosensory system: parallels with visual computation
Clarke, Stephen E., Longtin, André, Maler, Leonard
Published in Nature reviews. Neuroscience (01.12.2015)
Published in Nature reviews. Neuroscience (01.12.2015)
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Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach
GALETIN, Aleksandra, CLARKE, Stephen E, HOUSTON, J. Brian
Published in Drug metabolism and disposition (01.12.2002)
Published in Drug metabolism and disposition (01.12.2002)
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CYTOCHROME P450 GENE INDUCTION IN RATS EX VIVO ASSESSED BY QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (TAQMAN)
BALDWIN, Sandra J, BRAMHALL, Jo L, ASHBY, Charlotte A, LIN YUE, MURDOCK, Paul R, HOOD, Steven R, AYRTON, Andrew D, CLARKE, Stephen E
Published in Drug metabolism and disposition (01.06.2006)
Published in Drug metabolism and disposition (01.06.2006)
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Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
SANDERSON, Joseph P, HOLLIS, Frank J, MAGGS, James L, CLARKE, Stephen E, NAISBITT, Dean J, PARK, B. Kevin
Published in Drug metabolism and disposition (01.12.2008)
Published in Drug metabolism and disposition (01.12.2008)
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Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B57 : 01-restricted CD8+ T-cell activation
Naisbitt, Dean J, Yang, Emma L, Alhaidari, Mohammad, Berry, Neil G, Lawrenson, Alexandre S, Farrell, John, Martin, Philip, Strebel, Klaus, Owen, Andrew, Pye, Matthew, French, Neil S, Clarke, Stephen E, O’Neill, Paul M, Park, B Kevin
Published in AIDS (London) (28.11.2015)
Published in AIDS (London) (28.11.2015)
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Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation
Callan, Hayley E, Jenkins, Rosalind E, Maggs, James L, Lavergne, Sidonie N, Clarke, Stephen E, Naisbitt, Dean J, Park, B. Kevin
Published in Chemical research in toxicology (18.05.2009)
Published in Chemical research in toxicology (18.05.2009)
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FORMATION AND PROTEIN BINDING OF THE ACYL GLUCURONIDE OF A LEUKOTRIENE B4 ANTAGONIST (SB-209247): RELATION TO SPECIES DIFFERENCES IN HEPATOTOXICITY
KENNY, Jane R, MAGGS, James L, TETTEY, Justice N. A, HARRELL, Andrew W, PARKER, Steven G, CLARKE, Stephen E, PARK, B. Kevin
Published in Drug metabolism and disposition (01.02.2005)
Published in Drug metabolism and disposition (01.02.2005)
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Activation of T cells by carbamazepine and carbamazepine metabolites
Wu, Ying, Sanderson, Joseph P., Farrell, John, Drummond, Nicola S., Hanson, Anita, Bowkett, Elizabeth, Berry, Neil, Stachulski, Andrew V., Clarke, Stephen E., Pichler, Werner J., Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.
Published in Journal of Allergy and Clinical Immunology (01.07.2006)
Published in Journal of Allergy and Clinical Immunology (01.07.2006)
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