Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I
Kim, Nayun, Huang, Shar-yin N., Williams, Jessica S., Li, Yue C., Clark, Alan B., Cho, Jang-Eun, Kunkel, Thomas A., Pommier, Yves, Jinks-Robertson, Sue
Published in Science (American Association for the Advancement of Science) (24.06.2011)
Published in Science (American Association for the Advancement of Science) (24.06.2011)
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Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition
Lujan, Scott A, Clausen, Anders R, Clark, Alan B, MacAlpine, Heather K, MacAlpine, David M, Malc, Ewa P, Mieczkowski, Piotr A, Burkholder, Adam B, Fargo, David C, Gordenin, Dmitry A, Kunkel, Thomas A
Published in Genome research (01.11.2014)
Published in Genome research (01.11.2014)
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A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair
Smogorzewska, Agata, Desetty, Rohini, Saito, Takamune T., Schlabach, Michael, Lach, Francis P., Sowa, Mathew E., Clark, Alan B., Kunkel, Thomas A., Harper, J. Wade, Colaiácovo, Monica P., Elledge, Stephen J.
Published in Molecular cell (09.07.2010)
Published in Molecular cell (09.07.2010)
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Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
Schaetzlein, Sonja, Chahwan, Richard, Avdievich, Elena, Roa, Sergio, Wei, Kaichun, Eoff, Robert L, Sellers, Rani S, Clark, Alan B, Kunkel, Thomas A, Scharff, Matthew D, Edelmann, Winfried
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
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Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors
Lujan, Scott A., Williams, Jessica S., Clausen, Anders R., Clark, Alan B., Kunkel, Thomas A.
Published in Molecular cell (09.05.2013)
Published in Molecular cell (09.05.2013)
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An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents
Kucherlapati, Melanie H, Lee, Kyeryoung, Nguyen, Andrew A, Clark, Alan B, Hou, Jr, Harry, Rosulek, Andrew, Li, Hua, Yang, Kan, Fan, Kunhua, Lipkin, Martin, Bronson, Roderick T, Jelicks, Linda, Kunkel, Thomas A, Kucherlapati, Raju, Edelmann, Winfried
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2010)
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Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice
Schaetzlein, Sonja, Kodandaramireddy, N.R., Ju, Zhenyu, Lechel, Andre, Stepczynska, Anna, Lilli, Dana R., Clark, Alan B., Rudolph, Cornelia, Kuhnel, Florian, Wei, Kaichun, Schlegelberger, Brigitte, Schirmacher, Peter, Kunkel, Thomas A., Greenberg, Roger A., Edelmann, Winfried, Rudolph, K. Lenhard
Published in Cell (07.09.2007)
Published in Cell (07.09.2007)
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Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer
Dumstorf, Chad A, Clark, Alan B, Lin, Qingcong, Kissling, Grace E, Yuan, Tao, Kucherlapati, Raju, McGregor, W Glenn, Kunkel, Thomas A
Published in Proceedings of the National Academy of Sciences - PNAS (28.11.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.11.2006)
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Patient-directed self-management of pain (PaDSMaP) compared to treatment as usual following total knee replacement; a randomised controlled trial
Deane, Katherine H O, Gray, Richard, Balls, Paula, Darrah, Clare, Swift, Louise, Clark, Alan B, Barton, Garry R, Morris, Sophie, Butters, Sue, Bullough, Angela, Flaherty, Helen, Talbot, Barbara, Sanders, Mark, Donell, Simon T
Published in BMC health services research (10.05.2018)
Published in BMC health services research (10.05.2018)
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Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
Wei, Kaichun, Clark, Alan B, Wong, Edmund, Kane, Michael F, Mazur, Dan J, Parris, Tchaiko, Kolas, Nadine K, Russell, Robert, Hou, Jr, Harry, Kneitz, Burkhard, Yang, Guohze, Kunkel, Thomas A, Kolodner, Richard D, Cohen, Paula E, Edelmann, Winfried
Published in Genes & development (01.03.2003)
Published in Genes & development (01.03.2003)
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An Msh2 point mutation uncouples DNA mismatch repair and apoptosis
LIN, Diana P, YUXUN WANG, UMAR, Asad, KUCHERLAPATI, Raju, LIPKIN, Martin, KUNKEL, Thomas A, EDELMANN, Winfried, SCHERER, Stefan J, CLARK, Alan B, KAN YANG, AVDIEVICH, Elena, BO JIN, WERLING, Uwe, PARRIS, Tchaiko, KURIHARA, Naoto
Published in Cancer research (Chicago, Ill.) (15.01.2004)
Published in Cancer research (Chicago, Ill.) (15.01.2004)
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A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
Jirawatnotai, Siwanon, Hu, Yiduo, Michowski, Wojciech, Elias, Joshua E., Becks, Lisa, Bienvenu, Frederic, Zagozdzon, Agnieszka, Goswami, Tapasree, Wang, Yaoyu E., Clark, Alan B., Kunkel, Thomas A., van Harn, Tanja, Xia, Bing, Correll, Mick, Quackenbush, John, Livingston, David M., Gygi, Steven P., Sicinski, Piotr
Published in Nature (London) (08.06.2011)
Published in Nature (London) (08.06.2011)
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Genome instability due to ribonucleotide incorporation into DNA
Kunkel, Thomas A, McElhinny, Stephanie A Nick, Kumar, Dinesh, Clark, Alan B, Watt, Danielle L, Watts, Brian E, Lundström, Else-Britt, Johansson, Erik, Chabes, Andrei
Published in Nature chemical biology (01.10.2010)
Published in Nature chemical biology (01.10.2010)
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Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific
Williams, Jessica S, Clausen, Anders R, Lujan, Scott A, Marjavaara, Lisette, Clark, Alan B, Burgers, Peter M, Chabes, Andrei, Kunkel, Thomas A
Published in Nature structural & molecular biology (01.04.2015)
Published in Nature structural & molecular biology (01.04.2015)
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Stimulation of Chromosomal Rearrangements by Ribonucleotides
Conover, Hailey N, Lujan, Scott A, Chapman, Mary J, Cornelio, Deborah A, Sharif, Rabab, Williams, Jessica S, Clark, Alan B, Camilo, Francheska, Kunkel, Thomas A, Argueso, Juan Lucas
Published in Genetics (Austin) (01.11.2015)
Published in Genetics (Austin) (01.11.2015)
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