Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist
Whittle, Brendan J., Silverstein, Adam M., Mottola, David M., Clapp, Lucie H.
Published in Biochemical pharmacology (01.07.2012)
Published in Biochemical pharmacology (01.07.2012)
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International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
Norel, Xavier, Sugimoto, Yukihiko, Ozen, Gulsev, Abdelazeem, Heba, Amgoud, Yasmine, Bouhadoun, Amel, Bassiouni, Wesam, Goepp, Marie, Mani, Salma, Manikpurage, Hasanga D., Senbel, Amira, Longrois, Dan, Heinemann, Akos, Yao, Chengcan, Clapp, Lucie H.
Published in Pharmacological reviews (01.10.2020)
Published in Pharmacological reviews (01.10.2020)
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International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E 2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
Norel, Xavier, Sugimoto, Yukihiko, Ozen, Gulsev, Abdelazeem, Heba, Amgoud, Yasmine, Bouhadoun, Amel, Bassiouni, Wesam, Goepp, Marie, Mani, Salma, Manikpurage, Hasanga D, Senbel, Amira, Longrois, Dan, Heinemann, Akos, Yao, Chengcan, Clapp, Lucie H
Published in Pharmacological reviews (01.10.2020)
Published in Pharmacological reviews (01.10.2020)
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Thomas (Tom) B. Bolton – a major force in smooth muscle research
Zholos, Alexander V., Greenwood, Iain A., Lang, Rick J., Benham, Christopher D., Aaronson, Philip I., Garland, Christopher J., Weston, Arthur H., Prestwich, Sally A., Gordienko, Dmitri V., Povstyan, Oleksandr V., Zhang, Hailin, Clapp, Lucie H., Pucovsky, Vladimir, Tare, Marianne, Fenech, Claire J., Unno, Toshihiro, Muraki, Katsuhiko, Shi, Jian, Hughes, Alun D., Halstead, Thomas K., Beech, David J.
Published in The Journal of physiology (01.08.2024)
Published in The Journal of physiology (01.08.2024)
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Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells
Patel, Jigisha A, Shen, Lei, Hall, Susan M, Benyahia, Chabha, Norel, Xavier, McAnulty, Robin J, Moledina, Shahin, Silverstein, Adam M, Whittle, Brendan J, Clapp, Lucie H
Published in International journal of molecular sciences (12.08.2018)
Published in International journal of molecular sciences (12.08.2018)
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Exploring the enzymatic degradation of poly(glycerol adipate)
Swainson, Sadie M.E., Taresco, Vincenzo, Pearce, Amanda K., Clapp, Lucie H., Ager, Barry, McAllister, Mark, Bosquillon, Cynthia, Garnett, Martin C.
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2019)
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Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension
FALCETTI, Emilia, HALL, Susan M, PHILLIPS, Peter G, PATEL, Jigisha, MORRELL, Nicholas W, HAWORTH, Sheila G, CLAPP, Lucie H
Published in American journal of respiratory and critical care medicine (01.11.2010)
Published in American journal of respiratory and critical care medicine (01.11.2010)
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Relative Recovery of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Rats
Aboujassoum, Hamda M, Mohamed-Ali, Vidya, Abraham, David, Clapp, Lucie H, Al-Naemi, Hamda A
Published in Nutrients (28.12.2023)
Published in Nutrients (28.12.2023)
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Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension
Abu-Hanna, Jeries, Anastasakis, Evangelos, Patel, Jigisha A., Eddama, Mohammad Mahmoud Rajab, Denton, Christopher P., Taanman, Jan-Willem, Abraham, David, Clapp, Lucie H.
Published in Vascular pharmacology (01.08.2023)
Published in Vascular pharmacology (01.08.2023)
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Altered cyclooxygenase-1 and enhanced thromboxane receptor activities underlie attenuated endothelial dilatory capacity of omental arteries in obesity
Raees, Asmaa, Bakhamis, Aysha, Mohamed-Ali, Vidya, Bashah, Moataz, Al-Jaber, Mashael, Abraham, David, Clapp, Lucie H., Orie, Nelson N.
Published in Life sciences (1973) (15.12.2019)
Published in Life sciences (1973) (15.12.2019)
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Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension
Ozen, Gulsev, Benyahia, Chabha, Mani, Salma, Boukais, Kamel, Silverstein, Adam M., Bayles, Richard, Nelsen, Andrew C., Castier, Yves, Danel, Claire, Mal, Hervé, Clapp, Lucie H., Longrois, Dan, Norel, Xavier
Published in British journal of pharmacology (01.01.2020)
Published in British journal of pharmacology (01.01.2020)
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Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension
Shen, Lei, Patel, Jigisha A., Norel, Xavier, Moledina, Shahin, Whittle, Brendan J., von Kessler, Kirby, Sista, Prakash, Clapp, Lucie H.
Published in Biochemical pharmacology (01.08.2019)
Published in Biochemical pharmacology (01.08.2019)
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Inhibition of Phosphodiesterase 2 Augments cGMP and cAMP Signaling to Ameliorate Pulmonary Hypertension
Bubb, Kristen J, Trinder, Sarah L, Baliga, Reshma S, Patel, Jigisha, Clapp, Lucie H, MacAllister, Raymond J, Hobbs, Adrian J
Published in Circulation (New York, N.Y.) (05.08.2014)
Published in Circulation (New York, N.Y.) (05.08.2014)
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Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature
Abu-Hanna, Jeries, Patel, Jigisha A, Anastasakis, Evangelos, Cohen, Richard, Clapp, Lucie H, Loizidou, Marilena, Eddama, Mohammad M. R
Published in Clinical epigenetics (01.08.2022)
Published in Clinical epigenetics (01.08.2022)
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The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels
Cunningham, Kevin P., Clapp, Lucie H., Mathie, Alistair, Veale, Emma L.
Published in Frontiers in pharmacology (29.06.2021)
Published in Frontiers in pharmacology (29.06.2021)
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Bronchodilation induced by PGE 2 is impaired in Group III pulmonary hypertension
Ozen, Gulsev, Benyahia, Chabha, Mani, Salma, Boukais, Kamel, Silverstein, Adam M, Bayles, Richard, Nelsen, Andrew C, Castier, Yves, Danel, Claire, Mal, Hervé, Clapp, Lucie H, Longrois, Dan, Norel, Xavier
Published in British journal of pharmacology (01.01.2020)
Published in British journal of pharmacology (01.01.2020)
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Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients
Ozen, Gulsev, Benyahia, Chabha, Amgoud, Yasmine, Patel, Jigisha, Abdelazeem, Heba, Bouhadoun, Amel, Yung, Sonia, Li, Fangfang, Mahieddine, Youcef, Silverstein, Adam M., Castier, Yves, Cazes, Aurélie, Longrois, Dan, Clapp, Lucie H., Norel, Xavier
Published in Prostaglandins & other lipid mediators (01.02.2020)
Published in Prostaglandins & other lipid mediators (01.02.2020)
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