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Cortes, J.E, Kim, D.-W, Pinilla-Ibarz, J, le Coutre, P, Paquette, R, Chuah, C, Nicolini, F.E, Apperley, J.F, Khoury, H.J, Talpaz, M, DiPersio, J, DeAngelo, D.J, Abruzzese, E, Rea, D, Baccarani, M, Müller, M.C, Gambacorti-Passerini, C, Wong, S, Lustgarten, S, Rivera, V.M, Clackson, T, Turner, C.D, Haluska, F.G, Guilhot, F, Deininger, M.W, Hochhaus, A, Hughes, T, Goldman, J.M, Shah, N.P, Kantarjian, H
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Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial
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407 A Broad Tumor Cell Line Panel Screen of Ponatinib, a Pan-BCR-ABL and Multitargeted Kinase Inhibitor
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Published in European journal of cancer (1990) (01.11.2012)
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164 The Dual ALK/EGFR Inhibitor AP26113 Also Potently Inhibits
Anjum, R, Zhang, S, Squillace, R, Clackson, T, Garner, A.P, Rivera, V.M
Published in European journal of cancer (1990) (01.11.2012)
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81: Efficacy and safety of AP26113 in ALK+ non-small cell lung cancer (NSCLC), including patients with brain metastases
Gettinger, S.N, Bazhenova, L, Salgia, R, Langer, C.J, Gold, K.A, Rosell, R, Shaw, A.T, Weiss, G.J, Narasimhan, N.I, Dorer, D.J, Rivera, V.M, Clackson, T, Haluska, F.G, Camidge, D.R
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Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer
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Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands
WANG, J, VOUTETAKIS, A, PAPA, M, RIVERA, V. M, CLACKSON, T, LODDE, B. M, MINESHIBA, F, BAUM, B. J
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Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers
Iuliucci, J D, Oliver, S D, Morley, S, Ward, C, Ward, J, Dalgarno, D, Clackson, T, Berger, H J
Published in Journal of clinical pharmacology (01.08.2001)
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By-passing immunization: building high affinity human antibodies by chain shuffling
Marks, J D, Griffiths, A D, Malmqvist, M, Clackson, T P, Bye, J M, Winter, G
Published in Bio/technology (New York, N.Y. 1983) (01.07.1992)
Published in Bio/technology (New York, N.Y. 1983) (01.07.1992)
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Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands
Zheng, C, Voutetakis, A, Metzger, M, Afione, S, Cotrim, AP, Eckhaus, MA, Rivera, VM, Clackson, T, Chiorini, JA, Donahue, RE, Dunbar, CE, Baum, BJ
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324 POSTER Synergistic activity of the mTOR inhibitor deforolimus (AP23573; MK-8669) and the anti-androgen bicalutamide in prostate cancer models
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Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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553 POSTER AP24534: an orally active kinase inhibitor that targets multiple pro-angiogenic receptors and exhibits potent anti-tumor activity in vivo
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Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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321 POSTER A phase I trial evaluating pharmacodynamics of deforolimus (AP23573, MK-8669) delivered orally on multiple dosing schedules
Berk, L, Miller, D, Clapham, D, Loewy, J, Mita, M, Britten, C, Poplin, E, Bedrosian, C.L, Clackson, T, Rivera, V.M
Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
O'Hare, Thomas, Shakespeare, William C., Zhu, Xiaotian, Eide, Christopher A., Rivera, Victor M., Wang, Frank, Adrian, Lauren T., Zhou, Tianjun, Huang, Wei-Sheng, Xu, Qihong, Metcalf, Chester A., Tyner, Jeffrey W., Loriaux, Marc M., Corbin, Amie S., Wardwell, Scott, Ning, Yaoyu, Keats, Jeffrey A., Wang, Yihan, Sundaramoorthi, Raji, Thomas, Mathew, Zhou, Dong, Snodgrass, Joseph, Commodore, Lois, Sawyer, Tomi K., Dalgarno, David C., Deininger, Michael W.N., Druker, Brian J., Clackson, Tim
Published in Cancer cell (06.11.2009)
Published in Cancer cell (06.11.2009)
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Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer
Rivera, Victor M., Gao, Guang-ping, Grant, Rebecca L., Schnell, Michael A., Zoltick, Philip W., Rozamus, Leonard W., Clackson, Tim, Wilson, James M.
Published in Blood (15.02.2005)
Published in Blood (15.02.2005)
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