The therapeutic potential of second and third generation CB1R antagonists
Cinar, Resat, Iyer, Malliga R., Kunos, George
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
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Journal Article
Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD
Udi, Shiran, Hinden, Liad, Earley, Brian, Drori, Adi, Reuveni, Noa, Hadar, Rivka, Cinar, Resat, Nemirovski, Alina, Tam, Joseph
Published in Journal of the American Society of Nephrology (01.12.2017)
Published in Journal of the American Society of Nephrology (01.12.2017)
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Journal Article
Crystal Structure of the Human Cannabinoid Receptor CB2
Li, Xiaoting, Hua, Tian, Vemuri, Kiran, Ho, Jo-Hao, Wu, Yiran, Wu, Lijie, Popov, Petr, Benchama, Othman, Zvonok, Nikolai, Locke, K’ara, Qu, Lu, Han, Gye Won, Iyer, Malliga R., Cinar, Resat, Coffey, Nathan J., Wang, Jingjing, Wu, Meng, Katritch, Vsevolod, Zhao, Suwen, Kunos, George, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie
Published in Cell (24.01.2019)
Published in Cell (24.01.2019)
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Journal Article
Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
Jourdan, Tony, Godlewski, Grzegorz, Cinar, Resat, Bertola, Adeline, Szanda, Gergő, Liu, Jie, Tam, Joseph, Han, Tiffany, Mukhopadhyay, Bani, Skarulis, Monica C, Ju, Cynthia, Aouadi, Myriam, Czech, Michael P, Kunos, George
Published in Nature medicine (01.09.2013)
Published in Nature medicine (01.09.2013)
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Journal Article
Cholesterol as a modulator of cannabinoid receptor CB2 signaling
Yeliseev, Alexei, Iyer, Malliga R, Joseph, Thomas T, Coffey, Nathan J, Cinar, Resat, Zoubak, Lioudmila, Kunos, George, Gawrisch, Klaus
Published in Scientific reports (12.02.2021)
Published in Scientific reports (12.02.2021)
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Journal Article
Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
RAJESH, Mohanraj, BATKAI, Sándor, HASKO, Gyorgy, PACHER, Pál, KECHRID, Malek, MUKHOPADHYAY, Partha, LEE, Wen-Shin, HORVATH, Bela, HOLOVAC, Eileen, CINAR, Resat, LIAUDET, Lucas, MACKIE, Ken
Published in Diabetes (New York, N.Y.) (01.03.2012)
Published in Diabetes (New York, N.Y.) (01.03.2012)
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Journal Article
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy
Jourdan, Tony, Szanda, Gergő, Rosenberg, Avi Z, Tam, Joseph, Earley, Brian James, Godlewski, Grzegorz, Cinar, Resat, Liu, Ziyi, Liu, Jie, Ju, Cynthia, Pacher, Pál, Kunos, George
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2014)
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Journal Article
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization
Björnson, Elias, Mukhopadhyay, Bani, Asplund, Anna, Pristovsek, Nusa, Cinar, Resat, Romeo, Stefano, Uhlen, Mathias, Kunos, George, Nielsen, Jens, Mardinoglu, Adil
Published in Cell reports (Cambridge) (01.12.2015)
Published in Cell reports (Cambridge) (01.12.2015)
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Journal Article
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms
Mukhopadhyay, Bani, Schuebel, Kornel, Mukhopadhyay, Partha, Cinar, Resat, Godlewski, Grzegorz, Xiong, Keming, Mackie, Ken, Lizak, Martin, Yuan, Qiaoping, Goldman, David, Kunos, George
Published in Hepatology (Baltimore, Md.) (01.05.2015)
Published in Hepatology (Baltimore, Md.) (01.05.2015)
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Journal Article
Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance
Tam, Joseph, Cinar, Resat, Liu, Jie, Godlewski, Grzegorz, Wesley, Daniel, Jourdan, Tony, Szanda, Gergő, Mukhopadhyay, Bani, Chedester, Lee, Liow, Jeih-San, Innis, Robert B., Cheng, Kejun, Rice, Kenner C., Deschamps, Jeffrey R., Chorvat, Robert J., McElroy, John F., Kunos, George
Published in Cell metabolism (08.08.2012)
Published in Cell metabolism (08.08.2012)
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Journal Article
Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis
Godlewski, Grzegorz, Cinar, Resat, Coffey, Nathan J., Liu, Jie, Jourdan, Tony, Mukhopadhyay, Bani, Chedester, Lee, Liu, Ziyi, Osei-Hyiaman, Douglas, Iyer, Malliga R., Park, Joshua K., Smith, Roy G., Iwakura, Hiroshi, Kunos, George
Published in Cell metabolism (04.06.2019)
Published in Cell metabolism (04.06.2019)
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Journal Article
Chronic alcohol produces neuroadaptations to prime dorsal striatal learning
DePoy, Lauren, Daut, Rachel, Brigman, Jonathan L., MacPherson, Kathryn, Crowley, Nicole, Gunduz-Cinar, Ozge, Pickens, Charles L., Cinar, Resat, Saksida, Lisa M., Kunos, George, Lovinger, David M., Bussey, Timothy J., Camp, Marguerite C., Holmes, Andrew
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2013)
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Journal Article
Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors
Kundu, Biswajit, Dvorácskó, Szabolcs, Basu, Abhishek, Pommerolle, Lenny, Kim, Kyu Ah, Wood, Casey M, Gibbs, Eve, Behee, Madeline, Tarasova, Nadya I, Cinar, Resat, Iyer, Malliga R
Published in Molecules (Basel, Switzerland) (26.06.2024)
Published in Molecules (Basel, Switzerland) (26.06.2024)
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Journal Article
Network analyses identify liver‐specific targets for treating liver diseases
Lee, Sunjae, Zhang, Cheng, Liu, Zhengtao, Klevstig, Martina, Mukhopadhyay, Bani, Bergentall, Mattias, Cinar, Resat, Ståhlman, Marcus, Sikanic, Natasha, Park, Joshua K, Deshmukh, Sumit, Harzandi, Azadeh M, Kuijpers, Tim, Grøtli, Morten, Elsässer, Simon J, Piening, Brian D, Snyder, Michael, Smith, Ulf, Nielsen, Jens, Bäckhed, Fredrik, Kunos, George, Uhlen, Mathias, Boren, Jan, Mardinoglu, Adil
Published in Molecular systems biology (01.08.2017)
Published in Molecular systems biology (01.08.2017)
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Journal Article
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase
Liu, Jie, Cinar, Resat, Xiong, Keming, Godlewski, Grzegorz, Jourdan, Tony, Lin, Yuhong, Ntambi, James M., Kunos, George
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2013)
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Journal Article
Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Liu, Zhenhua, Yang, Nannan, Dong, Jie, Tian, Wotu, Chang, Lisa, Ma, Jinghong, Guo, Jifeng, Tan, Jieqiong, Dong, Ao, He, Kaikai, Zhou, Jingheng, Cinar, Resat, Wu, Junbing, Salinas, Armando G, Sun, Lixin, Kumar, Mantosh, Sullivan, Breanna T, Oldham, Braden B, Pitz, Vanessa, Makarious, Mary B, Ding, Jinhui, Kung, Justin, Xie, Chengsong, Hawes, Sarah L, Wang, Lupeng, Wang, Tao, Chan, Piu, Zhang, Zhuohua, Le, Weidong, Chen, Shengdi, Lovinger, David M, Blauwendraat, Cornelis, Singleton, Andrew B, Cui, Guohong, Li, Yulong, Cai, Huaibin, Tang, Beisha
Published in Nature communications (17.06.2022)
Published in Nature communications (17.06.2022)
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Journal Article
Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling
Tam, Joseph, Szanda, Gergő, Drori, Adi, Liu, Ziyi, Cinar, Resat, Kashiwaya, Yoshihiro, Reitman, Marc L., Kunos, George
Published in Molecular metabolism (Germany) (01.10.2017)
Published in Molecular metabolism (Germany) (01.10.2017)
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Journal Article
National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report
Wolff, Daniel, Radojcic, Vedran, Lafyatis, Robert, Cinar, Resat, Rosenstein, Rachel K., Cowen, Edward W., Cheng, Guang-Shing, Sheshadri, Ajay, Bergeron, Anne, Williams, Kirsten M., Todd, Jamie L., Teshima, Takanori, Cuvelier, Geoffrey D.E., Holler, Ernst, McCurdy, Shannon R., Jenq, Robert R., Hanash, Alan M., Jacobsohn, David, Santomasso, Bianca D., Jain, Sandeep, Ogawa, Yoko, Steven, Philipp, Luo, Zhonghui Katie, Dietrich-Ntoukas, Tina, Saban, Daniel, Bilic, Ervina, Penack, Olaf, Griffith, Linda M., Cowden, Meredith, Martin, Paul J., Greinix, Hildegard T., Sarantopoulos, Stefanie, Socie, Gerard, Blazar, Bruce R., Pidala, Joseph, Kitko, Carrie L., Couriel, Daniel R., Cutler, Corey, Schultz, Kirk R., Pavletic, Steven Z., Lee, Stephanie J., Paczesny, Sophie
Published in Transplantation and cellular therapy (01.10.2021)
Published in Transplantation and cellular therapy (01.10.2021)
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Conference Proceeding