Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity
I Ciftci, Halil, O Radwan, Mohamed, E Ozturk, Safiye, Ulusoy, N Gokce, Sozer, Ece, E Ellakwa, Doha, Ocak, Zeynep, Can, Mustafa, F S Ali, Taha, I Abd-Alla, Howaida, Yayli, Nurettin, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako
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Published in Molecules (Basel, Switzerland) (30.09.2019)
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Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
Sever, Belgin, Altıntop, Mehlika Dilek, Radwan, Mohamed O., Özdemir, Ahmet, Otsuka, Masami, Fujita, Mikako, Ciftci, Halil I.
Published in European journal of medicinal chemistry (15.11.2019)
Published in European journal of medicinal chemistry (15.11.2019)
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Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
Karabacak, Muhammed, Altıntop, Mehlika Dilek, İbrahim Çiftçi, Halil, Koga, Ryoko, Otsuka, Masami, Fujita, Mikako, Özdemir, Ahmet
Published in Molecules (Basel, Switzerland) (20.10.2015)
Published in Molecules (Basel, Switzerland) (20.10.2015)
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In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors
Sever, Belgin, Altıntop, Mehlika Dilek, Özdemir, Ahmet, Akalın Çiftçi, Gülşen, Ellakwa, Doha E, Tateishi, Hiroshi, Radwan, Mohamed O, Ibrahim, Mahmoud A A, Otsuka, Masami, Fujita, Mikako, Ciftci, Halil I, Ali, Taha F S
Published in Molecules (Basel, Switzerland) (07.11.2020)
Published in Molecules (Basel, Switzerland) (07.11.2020)
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Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition
Radwan, Mohamed O., Ciftci, Halil I., Ali, Taha F.S., Koga, Ryoko, Tateishi, Hiroshi, Nakata, Akiko, Ito, Akihiro, Yoshida, Minoru, Fujita, Mikako, Otsuka, Masami
Published in Bioorganic & medicinal chemistry letters (01.10.2020)
Published in Bioorganic & medicinal chemistry letters (01.10.2020)
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Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety
Altıntop, Mehlika Dilek, Ciftci, Halil Ibrahim, Radwan, Mohamed O, Sever, Belgin, Kaplancıklı, Zafer Asım, Ali, Taha F S, Koga, Ryoko, Fujita, Mikako, Otsuka, Masami, Özdemir, Ahmet
Published in Molecules (Basel, Switzerland) (27.12.2017)
Published in Molecules (Basel, Switzerland) (27.12.2017)
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Design, synthesis, and biological activity of Plastoquinone analogs as a new class of anticancer agents
Bayrak, Nilüfer, Yıldırım, Hatice, Yıldız, Mahmut, Radwan, Mohamed O., Otsuka, Masami, Fujita, Mikako, Tuyun, Amaç Fatih, Ciftci, Halil I.
Published in Bioorganic chemistry (01.11.2019)
Published in Bioorganic chemistry (01.11.2019)
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Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs
Ciftci, Halil I., Bayrak, Nilüfer, Yıldız, Mahmut, Yıldırım, Hatice, Sever, Belgin, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako, Tuyun, Amaç Fatih
Published in Bioorganic chemistry (01.09.2021)
Published in Bioorganic chemistry (01.09.2021)
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Structure based design, synthesis, and evaluation of anti-CML activity of the quinolinequinones as LY83583 analogs
Bayrak, Nilüfer, Ciftci, Halil I., Yıldız, Mahmut, Yıldırım, Hatice, Sever, Belgin, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako, Tuyun, Amaç Fatih
Published in Chemico-biological interactions (25.08.2021)
Published in Chemico-biological interactions (25.08.2021)
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Anticancer activity of Turkish marine extracts: a purple sponge extract induces apoptosis with multitarget kinase inhibition activity
Ciftci, Halil I., Can, Mustafa, Ellakwa, Doha E., Suner, Salih C., Ibrahim, Mohamed A., Oral, Ayhan, Sekeroglu, Nazim, Özalp, Barış, Otsuka, Masami, Fujita, Mikako, Alparslan, Mustafa, Radwan, Mohamed O.
Published in Investigational new drugs (01.10.2020)
Published in Investigational new drugs (01.10.2020)
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The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities
Ciftci, Halil Ibrahim, Ozturk, Safiye Emirdag, Ali, Taha F. S., Radwan, Mohamed O., Tateishi, Hiroshi, Koga, Ryoko, Ocak, Zeynep, Can, Mustafa, Otsuka, Masami, Fujita, Mikako
Published in Biological & pharmaceutical bulletin (01.04.2018)
Published in Biological & pharmaceutical bulletin (01.04.2018)
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Comparison of Mini-percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery in Preschool-aged Children
Pelit, Eyyup Sabri, Atis, Gökhan, Kati, Bülent, Akin, Yiğit, Çiftçi, Halil, Culpan, Meftun, Yeni, Ercan, Caskurlu, Turhan
Published in Urology (Ridgewood, N.J.) (01.03.2017)
Published in Urology (Ridgewood, N.J.) (01.03.2017)
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EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy
Ciftci, Halil I, Radwan, Mohamed O, Sever, Belgin, Hamdy, Ahmed K, Emirdağ, Safiye, Ulusoy, N Gokce, Sozer, Ece, Can, Mustafa, Yayli, Nurettin, Araki, Norie, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako, Altintop, Mehlika Dilek
Published in International journal of molecular sciences (11.10.2021)
Published in International journal of molecular sciences (11.10.2021)
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A novel series of chlorinated plastoquinone analogs: Design, synthesis, and evaluation of anticancer activity
Bayrak, Nilüfer, Yıldırım, Hatice, Yıldız, Mahmut, Radwan, Mohamed O., Otsuka, Masami, Fujita, Mikako, Ciftci, Halil I., Tuyun, Amaç Fatih
Published in Chemical biology & drug design (01.03.2020)
Published in Chemical biology & drug design (01.03.2020)
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A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors
Zeytün, Ebru, Altıntop, Mehlika D, Sever, Belgin, Özdemir, Ahmet, Ellakwa, Doha E, Ocak, Zeynep, Ciftci, Halil I, Otsuka, Masami, Fujita, Mikako, Radwan, Mohamed O
Published in Anti-cancer agents in medicinal chemistry (01.01.2021)
Published in Anti-cancer agents in medicinal chemistry (01.01.2021)
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Effects of N -acetylcysteine on Semen Parameters and Oxidative/Antioxidant Status
Ciftci, Halil, Verit, Ayhan, Savas, Murat, Yeni, Ercan, Erel, Ozcan
Published in Urology (Ridgewood, N.J.) (01.07.2009)
Published in Urology (Ridgewood, N.J.) (01.07.2009)
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Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells
Ciftci, Halil I., Bayrak, Nilüfer, Yıldırım, Hatice, Yıldız, Mahmut, Radwan, Mohamed O., Otsuka, Masami, Fujita, Mikako, Tuyun, Amaç F.
Published in Archiv der Pharmazie (Weinheim) (01.12.2019)
Published in Archiv der Pharmazie (Weinheim) (01.12.2019)
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Antiproliferative S -Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement
Radwan, Mohamed O, Ciftci, Halil I, Ali, Taha F S, Ellakwa, Doha E, Koga, Ryoko, Tateishi, Hiroshi, Nakata, Akiko, Ito, Akihiro, Yoshida, Minoru, Okamoto, Yoshinari, Fujita, Mikako, Otsuka, Masami
Published in Molecules (Basel, Switzerland) (10.09.2019)
Published in Molecules (Basel, Switzerland) (10.09.2019)
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