Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder
Galvani, Giuseppe, Mottolese, Nicola, Gennaccaro, Laura, Loi, Manuela, Medici, Giorgio, Tassinari, Marianna, Fuchs, Claudia, Ciani, Elisabetta, Trazzi, Stefania
Published in Journal of neuroinflammation (08.07.2021)
Published in Journal of neuroinflammation (08.07.2021)
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Journal Article
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
Trazzi, Stefania, Fuchs, Claudia, Viggiano, Rocchina, De Franceschi, Marianna, Valli, Emanuele, Jedynak, Paulina, Hansen, Finn K, Perini, Giovanni, Rimondini, Roberto, Kurz, Thomas, Bartesaghi, Renata, Ciani, Elisabetta
Published in Human molecular genetics (15.09.2016)
Published in Human molecular genetics (15.09.2016)
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Journal Article
Mapping pathological phenotypes in a mouse model of CDKL5 disorder
Amendola, Elena, Zhan, Yang, Mattucci, Camilla, Castroflorio, Enrico, Calcagno, Eleonora, Fuchs, Claudia, Lonetti, Giuseppina, Silingardi, Davide, Vyssotski, Alexei L, Farley, Dominika, Ciani, Elisabetta, Pizzorusso, Tommaso, Giustetto, Maurizio, Gross, Cornelius T
Published in PloS one (16.05.2014)
Published in PloS one (16.05.2014)
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Journal Article
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling
Fuchs, Claudia, Trazzi, Stefania, Torricella, Roberta, Viggiano, Rocchina, De Franceschi, Marianna, Amendola, Elena, Gross, Cornelius, Calzà, Laura, Bartesaghi, Renata, Ciani, Elisabetta
Published in Neurobiology of disease (01.10.2014)
Published in Neurobiology of disease (01.10.2014)
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Journal Article
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder
Tassinari, Marianna, Mottolese, Nicola, Galvani, Giuseppe, Ferrara, Domenico, Gennaccaro, Laura, Loi, Manuela, Medici, Giorgio, Candini, Giulia, Rimondini, Roberto, Ciani, Elisabetta, Trazzi, Stefania
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Journal Article
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling
Fuchs, Claudia, Medici, Giorgio, Trazzi, Stefania, Gennaccaro, Laura, Galvani, Giuseppe, Berteotti, Chiara, Ren, Elisa, Loi, Manuela, Ciani, Elisabetta
Published in Brain pathology (Zurich, Switzerland) (01.09.2019)
Published in Brain pathology (Zurich, Switzerland) (01.09.2019)
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Journal Article
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder
Tassinari, Marianna, Uguagliati, Beatrice, Trazzi, Stefania, Cerchier, Camilla Bruna, Cavina, Ottavia Vera, Mottolese, Nicola, Loi, Manuela, Candini, Giulia, Medici, Giorgio, Ciani, Elisabetta
Published in Neurobiology of disease (15.06.2023)
Published in Neurobiology of disease (15.06.2023)
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Journal Article
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
Loi, Manuela, Trazzi, Stefania, Fuchs, Claudia, Galvani, Giuseppe, Medici, Giorgio, Gennaccaro, Laura, Tassinari, Marianna, Ciani, Elisabetta
Published in Molecular neurobiology (01.05.2020)
Published in Molecular neurobiology (01.05.2020)
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Journal Article
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder
Fuchs, Claudia, Rimondini, Roberto, Viggiano, Rocchina, Trazzi, Stefania, De Franceschi, Marianna, Bartesaghi, Renata, Ciani, Elisabetta
Published in Neurobiology of disease (01.10.2015)
Published in Neurobiology of disease (01.10.2015)
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Journal Article
Timing of therapies for Down syndrome: the sooner, the better
Stagni, Fiorenza, Giacomini, Andrea, Guidi, Sandra, Ciani, Elisabetta, Bartesaghi, Renata
Published in Frontiers in behavioral neuroscience (06.10.2015)
Published in Frontiers in behavioral neuroscience (06.10.2015)
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Journal Article
Corrigendum to “APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome” [Neurobiology of Disease 67 (2014) 24–36]
Trazzi, Stefania, Fuchs, Claudia, De Franceschi, Marianna, Mitrugno, Valentina Maria, Bartesaghi, Renata, Ciani, Elisabetta
Published in Neurobiology of disease (01.05.2020)
Published in Neurobiology of disease (01.05.2020)
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Journal Article
CDKL5 deficiency entails sleep apneas in mice
Lo Martire, Viviana, Alvente, Sara, Bastianini, Stefano, Berteotti, Chiara, Silvani, Alessandro, Valli, Alice, Viggiano, Rocchina, Ciani, Elisabetta, Zoccoli, Giovanna
Published in Journal of sleep research (01.08.2017)
Published in Journal of sleep research (01.08.2017)
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Journal Article
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder
Gennaccaro, Laura, Fuchs, Claudia, Loi, Manuela, Roncacè, Vincenzo, Trazzi, Stefania, Ait-Bali, Yassine, Galvani, Giuseppe, Berardi, Anna Cecilia, Medici, Giorgio, Tassinari, Marianna, Ren, Elisa, Rimondini, Roberto, Giustetto, Maurizio, Aicardi, Giorgio, Ciani, Elisabetta
Published in Neurobiology of disease (01.06.2021)
Published in Neurobiology of disease (01.06.2021)
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Journal Article
The Amyloid Precursor Protein (APP) Triplicated Gene Impairs Neuronal Precursor Differentiation and Neurite Development through Two Different Domains in the Ts65Dn Mouse Model for Down Syndrome
Trazzi, Stefania, Fuchs, Claudia, Valli, Emanuele, Perini, Giovanni, Bartesaghi, Renata, Ciani, Elisabetta
Published in The Journal of biological chemistry (19.07.2013)
Published in The Journal of biological chemistry (19.07.2013)
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Journal Article
Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice
Stagni, Fiorenza, Giacomini, Andrea, Guidi, Sandra, Ciani, Elisabetta, Ragazzi, Elena, Filonzi, Mirco, De Iasio, Rosaria, Rimondini, Roberto, Bartesaghi, Renata
Published in Neurobiology of disease (01.02.2015)
Published in Neurobiology of disease (01.02.2015)
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Journal Article
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder
Loi, Manuela, Gennaccaro, Laura, Fuchs, Claudia, Trazzi, Stefania, Medici, Giorgio, Galvani, Giuseppe, Mottolese, Nicola, Tassinari, Marianna, Giorgini, Roberto Rimondini, Milelli, Andrea, Ciani, Elisabetta
Published in International journal of molecular sciences (31.05.2021)
Published in International journal of molecular sciences (31.05.2021)
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Journal Article
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome
Giacomini, Andrea, Stagni, Fiorenza, Trazzi, Stefania, Guidi, Sandra, Emili, Marco, Brigham, Elizabeth, Ciani, Elisabetta, Bartesaghi, Renata
Published in Neurobiology of disease (01.10.2015)
Published in Neurobiology of disease (01.10.2015)
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Journal Article
Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist
Ren, Elisa, Roncacé, Vincenzo, Trazzi, Stefania, Fuchs, Claudia, Medici, Giorgio, Gennaccaro, Laura, Loi, Manuela, Galvani, Giuseppe, Ye, Keqiang, Rimondini, Roberto, Aicardi, Giorgio, Ciani, Elisabetta
Published in Frontiers in cellular neuroscience (30.04.2019)
Published in Frontiers in cellular neuroscience (30.04.2019)
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Journal Article
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
Loi, Manuela, Bastianini, Stefano, Candini, Giulia, Rizzardi, Nicola, Medici, Giorgio, Papa, Valentina, Gennaccaro, Laura, Mottolese, Nicola, Tassinari, Marianna, Uguagliati, Beatrice, Berteotti, Chiara, Martire, Viviana Lo, Zoccoli, Giovanna, Cenacchi, Giovanna, Trazzi, Stefania, Bergamini, Christian, Ciani, Elisabetta
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation
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Journal Article
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