Respiratory syncytial virus fusion inhibitors. Part 7: Structure–activity relationships associated with a series of isatin oximes that demonstrate antiviral activity in vivo
Sin, Ny, Venables, Brian L., Combrink, Keith D., Gulgeze, H. Belgin, Yu, Kuo-Long, Civiello, Rita L., Thuring, Jan, Wang, X. Alan, Yang, Zheng, Zadjura, Lisa, Marino, Anthony, Kadow, Kathleen F., Cianci, Christopher W., Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Get full text
Journal Article
Respiratory syncytial virus fusion inhibitors. Part 4: Optimization for oral bioavailability
Yu, Kuo-Long, Sin, Ny, Civiello, Rita L., Wang, X. Alan, Combrink, Keith D., Gulgeze, H. Belgin, Venables, Brian L., Wright, J.J. Kim, Dalterio, Richard A., Zadjura, Lisa, Marino, Anthony, Dando, Sandra, D’Arienzo, Celia, Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Colonno, Richard J., Yang, Zheng, Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Get full text
Journal Article
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity
Wang, Xiangdong Alan, Cianci, Christopher W., Yu, Kuo-Long, Combrink, Keith D., Thuring, Jan W., Zhang, Yi, Civiello, Rita L., Kadow, Kathleen F., Roach, Julia, Li, Zhufang, Langley, David R., Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Get full text
Journal Article
Respiratory syncytial virus fusion inhibitors. Part 6: An examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety
Combrink, Keith D., Gulgeze, H. Belgin, Thuring, Jan W., Yu, Kuo-Long, Civiello, Rita L., Zhang, Yi, Pearce, Bradley C., Yin, Zhiwei, Langley, David R., Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Yang, Zheng, Zadjura, Lisa, Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Get full text
Journal Article
Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs
Bisacchi, Gregory S, Braitman, Abbe, Cianci, Christopher W, Clark, Junius M, Field, A. Kirk, Hagen, Moira E, Hockstein, Deborah R, Malley, Mary F, Mitt, Toomas
Published in Journal of medicinal chemistry (01.04.1991)
Published in Journal of medicinal chemistry (01.04.1991)
Get full text
Journal Article
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo
Yu, Kuo-Long, Wang, Xiangdong Alan, Civiello, Rita L., Trehan, Ashok K., Pearce, Bradley C., Yin, Zhiwei, Combrink, Keith D., Gulgeze, H. Belgin, Zhang, Yi, Kadow, Kathleen F., Cianci, Christopher W., Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Wyde, Philip R., Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Get full text
Journal Article
Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives
YU, Kuo-Long, YI ZHANG, CIANCI, Christopher W, KRYSTAL, Mark, MEANWELL, Nicholas A, CIVIELLO, Rita L, TREHAN, A. Ashok K, PEARCE, Bradley C, ZHIWEI YIN, COMBRINK, Keith D, GULGEZE, H. Belgin, WANG, Xiangdong Alan, KADOW, Kathleen F
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
Get full text
Journal Article
Development of a photoaffinity label for respiratory syncytial virus inhibitors
Dischino, Douglas D., Cianci, Christopher W., Civiello, Rita, Krystal, Mark, Meanwell, Nicholas A., Morimoto, Hiromi, Williams, Philip G., Yu, Kuo-Long
Published in Journal of labelled compounds & radiopharmaceuticals (31.10.2003)
Published in Journal of labelled compounds & radiopharmaceuticals (31.10.2003)
Get full text
Journal Article
Discovery and Development of Orally Active RSV Fusion Inhibitors
Meanwell, Nicholas A, Cianci, Christopher W, Krystal, Mark R
Published in Antiviral Drugs (08.08.2011)
Published in Antiviral Drugs (08.08.2011)
Get full text
Book Chapter
Antiviral Drug Discovery
Meanwell, Nicholas A, D'Andrea, Stanley V, Cianci, Christopher W, Dicker, Ira B, Yeung, Kap‐Sun, Belema, Makonen, Krystal, Mark
Published in Drug Discovery (2013)
Published in Drug Discovery (2013)
Get full text
Book Chapter
Corrigendum to “Respiratory syncytial virus fusion inhibitors. Part 4: Optimization for oral bioavailability” [Bioorg. Med. Chem. Lett. 17 (2007) 895–901]
Yu, Kuo-Long, Sin, Ny, Civiello, Rita L., Wang, X. Alan, Combrink, Keith D., Gulgeze, H. Belgin, Venables, Brian L., Kim Wright, J.J., Dalterio, Richard A., Zadjura, Lisa, Marino, Anthony, Dando, Sandra, D’Arienzo, Celia, Kadow, Kathleen F., Cianci, Christopher W., Li, Zhufang, Clarke, Junius, Genovesi, Eugene V., Medina, Ivette, Lamb, Lucinda, Colonno, Richard J., Yang, Zheng, Krystal, Mark, Meanwell, Nicholas A.
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Get full text
Journal Article
análogos de piperazina com grupos heteroarila substituídos como antivirais de influenza de amplo espectro
DAVID R. LANGLEY, GUO LI, WEIXU ZHAI, SEAN KIM, SHIRONG ZHU, SAMUEL GERRITZ, SHUHAO SHI, CHRISTOPHER W. CIANCI, ANNAPURNA PENDRI, BRADLEY C. PEARCE
Year of Publication 24.09.2019
Get full text
Year of Publication 24.09.2019
Patent
1,4-PIPERAZINE DERIVATIVES AS INFLUENZA ANTIVIRALS
ZHAI WEIXU, GERRITZ SAMUEL, LI GUO, SHI SHUHAO, CIANCI CHRISTOPHER, W, PEARCE BRADLEY, C, PENDRI ANNAPURNA, ZHU SHIRONG
Year of Publication 31.05.2016
Get full text
Year of Publication 31.05.2016
Patent
NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS
CIANCI, CHRISTOPHER W, PENDRI, ANNAPURNA, LI, GUO, ZHAI, WEIXU, GERRITZ, SAMUEL, PEARCE, BRADLEY C, ZHU, SHIRONG, SHI, SHUHAO
Year of Publication 31.08.2015
Get full text
Year of Publication 31.08.2015
Patent
NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS
CIANCI, CHRISTOPHER W, PENDRI, ANNAPURNA, LI, GUO, ZHAI, WEIXU, GERRITZ, SAMUEL, PEARCE, BRADLEY C, ZHU, SHIRONG, SHI, SHUHAO
Year of Publication 30.06.2015
Get full text
Year of Publication 30.06.2015
Patent
Nuovi analoghi di piperazina come antivirali ad ampio spettro per l'influenza
ZHAI WEIXU, GERRITZ SAMUEL, LI GUO, PENDRI ANNAPUMA, CIANCI CHRISTOPHER W, SHI SHUHAO, PEARCE BRADLEY C, ZHU SHIRONG
Year of Publication 05.05.2015
Get full text
Year of Publication 05.05.2015
Patent
NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS
ZHAI WEIXU, GERRITZ SAMUEL, LI GUO, CIANCI CHRISTOPHER W, SHI SHUHAO, PENDRI ANNAPURNA, PEARCE BRADLEY C, ZHU SHIRONG
Year of Publication 30.04.2015
Get full text
Year of Publication 30.04.2015
Patent
NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS
CIANCI, CHRISTOPHER W, PENDRI, ANNAPURNA, LI, GUO, ZHAI, WEIXU, GERRITZ, SAMUEL, PEARCE, BRADLEY C, ZHU, SHIRONG, SHI, SHUHAO
Year of Publication 10.04.2015
Get full text
Year of Publication 10.04.2015
Patent
HIDTIL UKENDTE PIPERAZINANALOGER SOM BREDSPEKTREREDE ANTIVIRALE INFLUENZAMIDLER
CIANCI, CHRISTOPHER, W, PENDRI, ANNAPURNA, LI, GUO, ZHAI, WEIXU, GERRITZ, SAMUEL, PEARCE, BRADLEY, C, ZHU, SHIRONG, SHI, SHUHAO
Year of Publication 07.04.2015
Get full text
Year of Publication 07.04.2015
Patent