SIRT6: Novel Mechanisms and Links to Aging and Disease
Tasselli, Luisa, Zheng, Wei, Chua, Katrin F
Published in Trends in endocrinology and metabolism (01.03.2017)
Published in Trends in endocrinology and metabolism (01.03.2017)
Get full text
Journal Article
Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives
You, Weijie, Zheng, Wei, Weiss, Sandra, Chua, Katrin F., Steegborn, Clemens
Published in Scientific reports (16.12.2019)
Published in Scientific reports (16.12.2019)
Get full text
Journal Article
Nuclear DNA damage signalling to mitochondria in ageing
Fang, Evandro Fei, Scheibye-Knudsen, Morten, Chua, Katrin F., Mattson, Mark P., Croteau, Deborah L., Bohr, Vilhelm A.
Published in Nature reviews. Molecular cell biology (01.05.2016)
Published in Nature reviews. Molecular cell biology (01.05.2016)
Get full text
Journal Article
SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence
Tasselli, Luisa, Xi, Yuanxin, Zheng, Wei, Tennen, Ruth I, Odrowaz, Zaneta, Simeoni, Federica, Li, Wei, Chua, Katrin F
Published in Nature structural & molecular biology (01.05.2016)
Published in Nature structural & molecular biology (01.05.2016)
Get full text
Journal Article
A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation
Moore, Kaitlyn E., Carlson, Scott M., Camp, Nathan D., Cheung, Peggie, James, Richard G., Chua, Katrin F., Wolf-Yadlin, Alejandro, Gozani, Or
Published in Molecular cell (09.05.2013)
Published in Molecular cell (09.05.2013)
Get full text
Journal Article
Molecular Pathways: Emerging Roles of Mammalian Sirtuin SIRT7 in Cancer
PAREDES, Silvana, VILLANOVA, Lidia, CHUA, Katrin F
Published in Clinical cancer research (01.04.2014)
Published in Clinical cancer research (01.04.2014)
Get full text
Journal Article
Chromatin regulation and genome maintenance by mammalian SIRT6
Tennen, Ruth I., Chua, Katrin F.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.01.2011)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.01.2011)
Get full text
Journal Article
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
Shin, Jiyung, He, Ming, Liu, Yufei, Paredes, Silvana, Villanova, Lidia, Brown, Katharine, Qiu, Xiaolei, Nabavi, Noushin, Mohrin, Mary, Wojnoonski, Kathleen, Li, Patrick, Cheng, Hwei-Ling, Murphy, Andrew J., Valenzuela, David M., Luo, Hanzhi, Kapahi, Pankaj, Krauss, Ronald, Mostoslavsky, Raul, Yancopoulos, George D., Alt, Frederick W., Chua, Katrin F., Chen, Danica
Published in Cell reports (Cambridge) (01.11.2013)
Published in Cell reports (Cambridge) (01.11.2013)
Get full text
Journal Article
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
Barber, Matthew F., Michishita-Kioi, Eriko, Xi, Yuanxin, Tasselli, Luisa, Kioi, Mitomu, Moqtaderi, Zarmik, Tennen, Ruth I., Paredes, Silvana, Young, Nicolas L., Chen, Kaifu, Struhl, Kevin, Garcia, Benjamin A., Gozani, Or, Li, Wei, Chua, Katrin F.
Published in Nature (London) (05.07.2012)
Published in Nature (London) (05.07.2012)
Get full text
Journal Article
Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules
You, Weijie, Rotili, Dante, Li, Tie‐Mei, Kambach, Christian, Meleshin, Marat, Schutkowski, Mike, Chua, Katrin F., Mai, Antonello, Steegborn, Clemens
Published in Angewandte Chemie International Edition (19.01.2017)
Published in Angewandte Chemie International Edition (19.01.2017)
Get full text
Journal Article
The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability
Paredes, Silvana, Angulo-Ibanez, Maria, Tasselli, Luisa, Carlson, Scott M., Zheng, Wei, Li, Tie-Mei, Chua, Katrin F.
Published in The Journal of biological chemistry (13.07.2018)
Published in The Journal of biological chemistry (13.07.2018)
Get full text
Journal Article
Elevated NSD3 histone methylation activity drives squamous cell lung cancer
Yuan, Gang, Flores, Natasha M., Hausmann, Simone, Lofgren, Shane M., Kharchenko, Vladlena, Angulo-Ibanez, Maria, Sengupta, Deepanwita, Lu, Xiaoyin, Czaban, Iwona, Azhibek, Dulat, Vicent, Silvestre, Fischle, Wolfgang, Jaremko, Mariusz, Fang, Bingliang, Wistuba, Ignacio I., Chua, Katrin F., Roth, Jack A., Minna, John D., Shao, Ning-Yi, Jaremko, Łukasz, Mazur, Pawel K., Gozani, Or
Published in Nature (London) (18.02.2021)
Published in Nature (London) (18.02.2021)
Get full text
Journal Article
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
Gozani, Or, Shi, Xiaobing, Hong, Tao, Walter, Kay L, Ewalt, Mark, Michishita, Eriko, Hung, Tiffany, Carney, Dylan, Peña, Pedro, Lan, Fei, Kaadige, Mohan R, Lacoste, Nicolas, Cayrou, Christelle, Davrazou, Foteini, Saha, Anjanabha, Cairns, Bradley R, Ayer, Donald E, Kutateladze, Tatiana G, Shi, Yang, Côté, Jacques, Chua, Katrin F
Published in Nature (06.07.2006)
Published in Nature (06.07.2006)
Get full text
Journal Article
HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies
Slaughter, Mariesa J., Shanle, Erin K., Khan, Abid, Chua, Katrin F., Hong, Tao, Boxer, Lisa D., Allis, C. David, Josefowicz, Steven Z., Garcia, Benjamin A., Rothbart, Scott B., Strahl, Brian D., Davis, Ian J.
Published in Cell reports (Cambridge) (19.01.2021)
Published in Cell reports (Cambridge) (19.01.2021)
Get full text
Journal Article
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors
Malik, Shivani, Villanova, Lidia, Tanaka, Shinji, Aonuma, Misato, Roy, Nilotpal, Berber, Elisabeth, Pollack, Jonathan R., Michishita-Kioi, Eriko, Chua, Katrin F.
Published in Scientific reports (29.04.2015)
Published in Scientific reports (29.04.2015)
Get full text
Journal Article
A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7
Wang, Wesley Wei, Angulo-Ibanez, Maria, Lyu, Jie, Kurra, Yadagiri, Tong, Zhen, Wu, Bo, Zhang, Ling, Sharma, Vangmayee, Zhou, Jennifer, Lin, Hening, Gao, Yi Qin, Li, Wei, Chua, Katrin F, Liu, Wenshe Ray
Published in Journal of the American Chemical Society (13.02.2019)
Published in Journal of the American Chemical Society (13.02.2019)
Get full text
Journal Article
SIRT6 is required for maintenance of telomere position effect in human cells
Tennen, Ruth I., Bua, Dennis J., Wright, Woodring E., Chua, Katrin F.
Published in Nature communications (16.08.2011)
Published in Nature communications (16.08.2011)
Get full text
Journal Article
The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells
Sharma, Amit, Diecke, Sebastian, Zhang, Wendy Y., Lan, Feng, He, Chunjiang, Mordwinkin, Nicholas M., Chua, Katrin F., Wu, Joseph C.
Published in The Journal of biological chemistry (21.06.2013)
Published in The Journal of biological chemistry (21.06.2013)
Get full text
Journal Article