Enantioselective Organocatalytic Construction of Pyrroloindolines by a Cascade Addition-Cyclization Strategy: Synthesis of (-)-Flustramine B
Austin, Joel F., Kim, Sung-Gon, Sinz, Christopher J., Xiao, Wen-Jing, David W. C. Mac Millan, Halpern, Jack
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2004)
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Design, Synthesis, and Evaluation of Novel and Selective G‑protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists
Cox, Jason M, Chu, Hong D, Chelliah, Mariappan V, Debenham, John S, Eagen, Keith, Lan, Ping, Lombardo, Matthew, London, Clare, Plotkin, Michael A, Shah, Unmesh, Sun, Zhongxiang, Vaccaro, Henry M, Venkatraman, Srikanth, Suzuki, Takao, Wang, Nengxue, Ashley, Eric R, Crespo, Alejandro, Madeira, Maria, Leung, Dennis H, Alleyne, Candice, Ogawa, Aimie M, Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam, Kirkland, Melissa, Pachanski, Michele, Powles, Mary Ann, Tozzo, Effie, Akiyama, Taro E, Ujjainwalla, Feroze, Tata, James R, Sinz, Christopher J
Published in ACS medicinal chemistry letters (12.01.2017)
Published in ACS medicinal chemistry letters (12.01.2017)
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Small molecule glucagon receptor antagonists: an updated patent review (2015-2019)
Cheng, Chen, Jabri, Salman, Taoka, Brandon M, Sinz, Christopher J
Published in Expert opinion on therapeutic patents (02.07.2020)
Published in Expert opinion on therapeutic patents (02.07.2020)
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
Engelstoft, Maja S, Park, Won-mee, Sakata, Ichiro, Kristensen, Line V, Husted, Anna Sofie, Osborne-Lawrence, Sherri, Piper, Paul K, Walker, Angela K, Pedersen, Maria H, Nøhr, Mark K, Pan, Jie, Sinz, Christopher J, Carrington, Paul E, Akiyama, Taro E, Jones, Robert M, Tang, Cong, Ahmed, Kashan, Offermanns, Stefan, Egerod, Kristoffer L, Zigman, Jeffrey M, Schwartz, Thue W
Published in Molecular metabolism (Germany) (01.11.2013)
Published in Molecular metabolism (Germany) (01.11.2013)
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Journal Article
Selective N7 Alkylation of 7-Azaindazoles
Lei, Zhiyu, Bao, Jianming, Cheng, Chen, Yu, Wensheng, Hu, Bin, Jin, Weichen, Jabri, Salman, Yang, Song, Zhao, Lianyun, Sinz, Christopher J., Duffy, Joseph L.
Published in Journal of organic chemistry (05.06.2020)
Published in Journal of organic chemistry (05.06.2020)
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Journal Article
Total synthesis of diazonamide A
Knowles, Robert R, Carpenter, Joseph, Blakey, Simon B, Kayano, Akio, Mangion, Ian K, Sinz, Christopher J, Macmillan, David W C
Published in Chemical science (Cambridge) (01.01.2011)
Published in Chemical science (Cambridge) (01.01.2011)
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Journal Article
The Direct and Enantioselective Organocatalytic α-Oxidation of Aldehydes
Brown, Sean P, Brochu, Michael P, Sinz, Christopher J, MacMillan, David W. C
Published in Journal of the American Chemical Society (10.09.2003)
Published in Journal of the American Chemical Society (10.09.2003)
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Journal Article
Modeling a Crowdsourced Definition of Molecular Complexity
Sheridan, Robert P, Zorn, Nicolas, Sherer, Edward C, Campeau, Louis-Charles, Chang, Charlie (Zhenyu), Cumming, Jared, Maddess, Matthew L, Nantermet, Philippe G, Sinz, Christopher J, O’Shea, Paul D
Published in Journal of chemical information and modeling (23.06.2014)
Published in Journal of chemical information and modeling (23.06.2014)
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Journal Article
Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects
Lombardo, Matthew, Bender, Kate, London, Clare, Plotkin, Michael A., Kirkland, Melissa, Mane, Joel, Pachanski, Michele, Geissler, Wayne, Cummings, John, Habulihaz, Bahanu, Akiyama, Taro E., Di Salvo, Jerry, Madeira, Maria, Pols, Joanna, Powles, Mary Ann, Finley, Michael F., Johnson, Eric, Roussel, Thomas, Uebele, Victor N., Crespo, Alejandro, Leung, Dennis, Alleyne, Candice, Trusca, Dorina, Lei, Ying, Howard, Andrew D., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
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Journal Article
Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia
Liu, Ping, Wang, Liping, DuBois, Byron G, Colandrea, Vincent J, Liu, Rongqiang, Cai, Jiaqiang, Du, Xiaoxing, Quan, Weiguo, Morris, William, Bai, Jianwu, Bishwokarma, Bimjhana, Cheng, Mangeng, Piesvaux, Jennifer, Ray, Kallol, Alpert, Carla, Chiu, Chi-Sung, Zielstorff, Mark, Metzger, Joseph M, Yang, Liming, Leung, Dennis, Alleyne, Candice, Vincent, Stella H, Pucci, Vincenzo, Li, Xiaofang, Crespo, Alejandro, Stickens, Dominique, Hale, Jeffrey J, Ujjainwalla, Feroze, Sinz, Christopher J
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
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Journal Article
Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters
Chen, Zhu, Wang, Sheng-ping, Krsmanovic, Mihajlo L, Castro-Perez, Jose, Gagen, Karen, Mendoza, Vivienne, Rosa, Ray, Shah, Vinit, He, Timothy, Stout, Steve J, Geoghagen, Neil S, Lee, Sang H, McLaren, David G, Wang, Liangsu, Roddy, Thomas P, Plump, Andrew S, Hubbard, Brian K, Sinz, Christopher J, Johns, Douglas G
Published in Metabolism, clinical and experimental (01.04.2012)
Published in Metabolism, clinical and experimental (01.04.2012)
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Journal Article
Corrigendum to “Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects” [Bioorg. Med. Chem. Lett. 26 (2016) 5724–5728]
Lombardo, Matthew, Bender, Kate, London, Clare, Plotkin, Michael A., Kirkland, Melissa, Mane, Joel, Pachanski, Michele, Geissler, Wayne, Cummings, John, Habulihaz, Bahanu, Akiyama, Taro E., Di Salvo, Jerry, Madeira, Maria, Pols, Joanna, Powles, Mary Ann, Finley, Michael F., Johnson, Eric, Roussel, Thomas, Uebele, Victor N., Crespo, Alejandro, Leung, Dennis, Alleyne, Candice, Trusca, Dorina, Lei, Ying, Howard, Andrew D., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
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Journal Article
Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes
Guo, Liangqin, Parker, Dann L, Zang, Yi, Sweis, Ramzi F, Liu, Weiguo, Sherer, Edward C, Buist, Nicole, Terebetski, Jenna, Kelly, Terri, Bugianesi, Randal, Priest, Birgit T, Dingley, Karen H, Li, Xiaofang, Mitelman, Stan, Salituro, Gino, Trujillo, Maria E, Pachanski, Michele, Kirkland, Melissa, Powles, Mary Ann, Eiermann, George J, Feng, Yue, Shang, Jin, Howard, Andrew D, Ujjainwalla, Feroze, Sinz, Christopher J, Debenham, John S, Edmondson, Scott D, Nargund, Ravi P, Hagmann, William K, Li, Derun
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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Total Synthesis of Dermostatin A
Sinz, Christopher J., Rychnovsky, Scott D.
Published in Angewandte Chemie (International ed.) (03.09.2001)
Published in Angewandte Chemie (International ed.) (03.09.2001)
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Journal Article
Total synthesis of diazonamide AElectronic supplementary information (ESI) available: Experimental procedures, structural proofs, and spectral data for all new compounds are provided. See DOI: 10.1039/c0sc00577k
Knowles, Robert R, Carpenter, Joseph, Blakey, Simon B, Kayano, Akio, Mangion, Ian K, Sinz, Christopher J, MacMillan, David W. C
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Year of Publication 01.02.2011
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Journal Article
Abstract 17305: Activation of Soluble Guanylate Cyclase Ameliorates the Progression of Glucose Intolerance and Nephropathy in Obese ZSF1 Rats
da Cunha, Valdeci, Shah, Kashmira, Price, Olga, Sinz, Christopher J, Kim, Ronald M
Published in Circulation (New York, N.Y.) (11.11.2016)
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Published in Circulation (New York, N.Y.) (11.11.2016)
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