Synthesis of (+)-Didemniserinolipid B: Application of a 2-Allyl-4-fluorophenyl Auxiliary for Relay Ring-Closing Metathesis
Marvin, Christopher C, Voight, Eric A, Suh, Judy M, Paradise, Christopher L, Burke, Steven D
Published in Journal of organic chemistry (07.11.2008)
Published in Journal of organic chemistry (07.11.2008)
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Journal Article
Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody–Drug Conjugate Payloads
Hobson, Adrian D, McPherson, Michael J, Waegell, Wendy, Goess, Christian A, Stoffel, Robert H, Li, Xiang, Zhou, Jian, Wang, Zhongyuan, Yu, Yajie, Hernandez, Axel, Bryant, Shaughn H, Mathieu, Suzanne L, Bischoff, Agnieszka K, Fitzgibbons, Julia, Pawlikowska, Martyna, Puthenveetil, Sujiet, Santora, Ling C, Wang, Lu, Wang, Lu, Marvin, Christopher C, Hayes, Martin E, Shrestha, Anurupa, Sarris, Kathy A, Li, Biqin
Published in Journal of medicinal chemistry (24.03.2022)
Published in Journal of medicinal chemistry (24.03.2022)
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Journal Article
Optimization of Drug-Linker to Enable Long-term Storage of Antibody–Drug Conjugate for Subcutaneous Dosing
Hobson, Adrian D., Xu, Jianwen, Marvin, Christopher C., McPherson, Michael J., Hollmann, Markus, Gattner, Michael, Dzeyk, Kristina, Fettis, Margaret M., Bischoff, Agnieszka K., Wang, Lu, Fitzgibbons, Julia, Wang, Lu, Salomon, Paulin, Hernandez, Axel, Jia, Ying, Sarvaiya, Hetal, Goess, Christian A., Mathieu, Suzanne L., Santora, Ling C.
Published in Journal of medicinal chemistry (13.07.2023)
Published in Journal of medicinal chemistry (13.07.2023)
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Journal Article
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody–Drug Conjugates
Marvin, Christopher C., Hobson, Adrian D., McPherson, Michael, Dunstan, Theresa A., Vargo, Thomas R., Hayes, Martin E., Fettis, Margaret M., Bischoff, Agnieszka, Wang, Lu, Wang, Lu, Hernandez, Axel, Jia, Ying, Oh, Jason Z., Tian, Yu
Published in Bioconjugate chemistry (18.10.2023)
Published in Bioconjugate chemistry (18.10.2023)
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Journal Article
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC)
Hobson, Adrian D., Xu, Jianwen, Welch, Dennie S., Marvin, Christopher C., McPherson, Michael J., Gates, Bradley, Liao, Xiaoli, Hollmann, Markus, Gattner, Michael J., Dzeyk, Kristina, Sarvaiya, Hetal, Shenoy, Vikram M., Fettis, Margaret M., Bischoff, Agnieszka K., Wang, Lu, Santora, Ling C., Wang, Lu, Fitzgibbons, Julia, Salomon, Paulin, Hernandez, Axel, Jia, Ying, Goess, Christian A., Mathieu, Suzanne L., Bryant, Shaughn H., Larsen, Mary E., Cui, Baoliang, Tian, Yu
Published in Journal of medicinal chemistry (14.09.2023)
Published in Journal of medicinal chemistry (14.09.2023)
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Journal Article
Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Marvin, Christopher C., Hobson, Adrian D., McPherson, Michael J., Hayes, Martin E., Patel, Meena V., Schmidt, Diana L., Li, Tongmei, Randolph, John T., Bischoff, Agnieszka K., Fitzgibbons, Julia, Wang, Lu, Wang, Lu, Hernandez, Axel, Jia, Ying, Goess, Christian A., Bryant, Shaughn H., Mathieu, Suzanne L., Xu, Jianwen
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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Journal Article
Synthesis of (±)-Tetrabenazine by Visible Light Photoredox Catalysis
Orgren, Lindsey R, Maverick, Emily E, Marvin, Christopher C
Published in Journal of organic chemistry (18.12.2015)
Published in Journal of organic chemistry (18.12.2015)
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Journal Article
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate
Hobson, Adrian D., McPherson, Michael J., Hayes, Martin E., Goess, Christian, Li, Xiang, Zhou, Jian, Wang, Zhongyuan, Yu, Yajie, Yang, Jindong, Sun, Liang, Zhang, Qiang, Qu, Pei, Yang, Shi, Hernandez, Axel, Bryant, Shaughn H., Mathieu, Suzanne L., Bischoff, Agnieszka K., Fitzgibbons, Julia, Santora, Ling C., Wang, Lu, Wang, Lu, Fettis, Margaret M., Li, Xiaofeng, Marvin, Christopher C., Wang, Zhi, Patel, Meena V., Schmidt, Diana L., Li, Tongmei, Randolph, John T., Henry, Rodger F., Graff, Candace, Tian, Yu, Aguirre, Ana L., Shrestha, Anurupa
Published in Journal of medicinal chemistry (08.12.2022)
Published in Journal of medicinal chemistry (08.12.2022)
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Journal Article
ABBV-319: a CD19-targeting glucocorticoid receptor modulator antibody-drug conjugate therapy for B-cell malignancies
Chang, Chewei Anderson, Emberley, Ethan, D'Souza, Aloma L., Zhao, Weilong, Cosgrove, Cormac, Parrish, Karen, Mitra, Diya, Payson, Elmer, Oleksijew, Anatol, Ellis, Paul, Rodriguez, Luis, Duggan, Ryan, Hrusch, Cara, Lasko, Loren, Assaily, Wissam, Zheng, Pingping, Liu, Wei, Hernandez, Axel, McCarthy, Kimberley, Zhang, Zhaomei, Rha, Geunbae, Cao, Zhensheng, Li, Yingchun, Perng, Olivia, Campbell, Jos, Zhang, Gloria, Curran, Tyler, Bruncko, Milan, Marvin, Christopher C., Hobson, Adrian, McPherson, Michael, Uziel, Tamar, Pysz, Marybeth A., Zhao, Xi, Bankovich, Alex, Hayflick, Joel, McDevitt, Michael, Freise, Kevin J., Morgan-Lappe, Susan, Purcell, James W.
Published in Blood (15.08.2024)
Published in Blood (15.08.2024)
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Journal Article
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases
McPherson, Michael J, Hobson, Adrian D, Hernandez, Jr, Axel, Marvin, Christopher C, Waegell, Wendy, Goess, Christian, Oh, Jason Z, Shi, Dan, Hayes, Martin E, Wang, Lu, Wang, Lu, Schmidt, Diana, Wang, Zhi, Pitney, Victoria, McCarthy, Kimberley, Jia, Ying, Wang, Ce, Kang, Bit Na, Bryant, Shaughn, Mathieu, Suzanne, Ruzek, Melanie, Parmentier, Julie, D'Cunha, Ronilda R, Pang, Yinuo, Phillips, Lucy, Brown, Nathan J, Xu, Jianwen, Graff, Candace, Tian, Yu, Longenecker, Kenton L, Qiu, Wei, Zhu, Haizhong, Liu, Wei, Zheng, Pingping, Bi, Yingtao, Stoffel, Robert
Published in Science translational medicine (20.03.2024)
Published in Science translational medicine (20.03.2024)
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Journal Article
Correction to “Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody–Drug Conjugate Payloads”
Hobson, Adrian D., McPherson, Michael J., Waegell, Wendy, Goess, Christian A., Stoffel, Robert H., Li, Xiang, Zhou, Jian, Wang, Zhongyuan, Yu, Yajie, Hernandez, Axel, Bryant, Shaughn H., Mathieu, Suzanne L., Bischoff, Agnieszka K., Fitzgibbons, Julia, Pawlikowska, Martyna, Puthenveetil, Sujiet, Santora, Ling C., Wang, Lu, Wang, Lu, Marvin, Christopher C., Hayes, Martin E., Shrestha, Anurupa, Sarris, Kathy A., Li, Biqin
Published in Journal of medicinal chemistry (27.04.2023)
Published in Journal of medicinal chemistry (27.04.2023)
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Journal Article
Correction to “Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate”
Hobson, Adrian D., McPherson, Michael J., Hayes, Martin E., Goess, Christian, Li, Xiang, Zhou, Jian, Wang, Zhongyuan, Yu, Yajie, Yang, Jindong, Sun, Liang, Zhang, Qiang, Qu, Pei, Yang, Shi, Hernandez, Axel, Bryant, Shaughn H., Mathieu, Suzanne L., Bischoff, Agnieszka K., Fitzgibbons, Julia, Santora, Ling C., Wang, Lu, Wang, Lu, Fettis, Margaret M., Li, Xiaofeng, Marvin, Christopher C., Wang, Zhi, Patel, Meena V., Schmidt, Diana L., Li, Tongmei, Randolph, John T., Henry, Rodger F., Graff, Candace, Tian, Yu, Aguirre, Ana L., Shrestha, Anurupa
Published in Journal of medicinal chemistry (27.04.2023)
Published in Journal of medicinal chemistry (27.04.2023)
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Journal Article
Synthesis of A‑9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt
Marvin, Christopher C., Greszler, Stephen N., Shelat, Bhadra H., Voight, Eric A.
Published in ACS omega (06.12.2022)
Published in ACS omega (06.12.2022)
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Journal Article
Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virus
Chris Krueger, A., Chen, Hui-Ju, Randolph, John T., Brown, Brian S., Halvorsen, Geoff T., Heyman, Howard R., Li, Tongmei, Marvin, Christopher C., Shanley, Jason P., Voight, Eric A., Bow, Daniel A.J., Van Handel, Cecilia, Peterkin, Vincent, Carr, Robert A., Stolarik, DeAnne, Dekhtyar, Tatyana, Irvin, Michelle L., Krishnan, Preethi, Henry, Rodger F., Wagner, Rolf, DeGoey, David A.
Published in Bioorganic & medicinal chemistry (01.01.2020)
Published in Bioorganic & medicinal chemistry (01.01.2020)
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Journal Article
Novel Lavendamycin Analogues as Antitumor Agents: Synthesis, in Vitro Cytotoxicity, Structure−Metabolism, and Computational Molecular Modeling Studies with NAD(P)H:Quinone Oxidoreductase 1
Hassani, Mary, Cai, Wen, Holley, David C, Lineswala, Jayana P, Maharjan, Babu R, Ebrahimian, G. Reza, Seradj, Hassan, Stocksdale, Mark G, Mohammadi, Farahnaz, Marvin, Christopher C, Gerdes, John M, Beall, Howard D, Behforouz, Mohammad
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Journal Article
ANTI-CD19 ANTIBODY-DRUG CONJUGATES
A CHEWEI CHANG, ETHAN D EMBERLEY, JAMES W PURCELL, ADRIAN D HOBSON, CHRISTOPHER C MARVIN
Year of Publication 28.12.2023
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Year of Publication 28.12.2023
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