Improved glucose control and reduced body weight in rodents with dual mechanism of action peptide hybrids
Trevaskis, James L, Mack, Christine M, Sun, Chengzao, Soares, Christopher J, D'Souza, Lawrence J, Levy, Odile E, Lewis, Diane Y, Jodka, Carolyn M, Tatarkiewicz, Krystyna, Gedulin, Bronislava, Gupta, Swati, Wittmer, Carrie, Hanley, Michael, Forood, Bruce, Parkes, David G, Ghosh, Soumitra S
Published in PloS one (22.10.2013)
Published in PloS one (22.10.2013)
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Journal Article
Enhanced Amylin-Mediated Body Weight Loss in Estradiol-Deficient Diet-Induced Obese Rats
Trevaskis, James L, Turek, Victoria F, Wittmer, Carrie, Griffin, Peter S, Wilson, Julie K, Reynolds, James M, Zhao, Yu, Mack, Christine M, Parkes, David G, Roth, Jonathan D
Published in Endocrinology (Philadelphia) (01.12.2010)
Published in Endocrinology (Philadelphia) (01.12.2010)
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Combination Therapy with Amylin and Peptide YY[3–36] in Obese Rodents: Anorexigenic Synergy and Weight Loss Additivity
Roth, Jonathan D, Coffey, Todd, Jodka, Carolyn M, Maier, Holly, Athanacio, Jennifer R, Mack, Christine M, Weyer, Christian, Parkes, David G
Published in Endocrinology (Philadelphia) (01.12.2007)
Published in Endocrinology (Philadelphia) (01.12.2007)
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Discovery and evaluation of pyrazolo[1,5- a]pyrimidines as neuropeptide Y1 receptor antagonists
Griffith, David A., Hargrove, Diane M., Maurer, Tristan S., Blum, Charles A., De Lombaert, Stéphane, Inthavongsay, John K., Klade, Lee E., Mack, Christine M., Rose, Colin R., Sanders, Martin J., Carpino, Philip A.
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
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Journal Article
PYY[3-36] Administration Decreases the Respiratory Quotient and Reduces Adiposity in Diet-Induced Obese Mice
Adams, Sean H, Lei, Chunli, Jodka, Carolyn M, Nikoulina, Svetlana E, Hoyt, Julie A, Gedulin, Bronislava, Mack, Christine M, Kendall, Eric S
Published in The Journal of nutrition (2006)
Published in The Journal of nutrition (2006)
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Structure-activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists
ELLIOTT, Richard L, OLIVER, Robert M, MACK, Christine M, CASSELLA, James V, LAFLAMME, Janet A, GILLASPY, Melissa L, HAMMOND, Marlys, HANK, Richard F, MAURER, Tristan S, BAKER, Demetria L, DASILVA-JARDINE, Paul A, STEVENSON, Ralph W
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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In Vitro and in Vivo Characterization of 3-{2-[6-(2-tert-Butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl}benzonitrile Hydrochloride Salt, a Potent and Selective NPY5 Receptor Antagonist
Elliott, Richard L, Oliver, Robert M, Hammond, Marlys, Patterson, Terrell A, She, Li, Hargrove, Diane M, Martin, Kelly A, Maurer, Tristan S, Kalvass, J. Cory, Morgan, Bradley P, DaSilva-Jardine, Paul A, Stevenson, Ralph W, Mack, Christine M, Cassella, James V
Published in Journal of medicinal chemistry (27.02.2003)
Published in Journal of medicinal chemistry (27.02.2003)
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Structure–activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres
Hammond, Marlys, Elliott, Richard L., Gillaspy, Melissa L., Hager, David C., Hank, Richard F., LaFlamme, Janet A., Oliver, Robert M., DaSilva-Jardine, Paul A., Stevenson, Ralph W., Mack, Christine M., Cassella, James V.
Published in Bioorganic & medicinal chemistry letters (16.06.2003)
Published in Bioorganic & medicinal chemistry letters (16.06.2003)
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Sex differences in the distribution of axon types within the genu of the rat corpus callosum
Mack, Christine M., Boehm, Gary W., Berrebi, Albert S., Denenberg, Victor H.
Published in Brain research (30.10.1995)
Published in Brain research (30.10.1995)
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Journal Article
PYY[3-36] Administration Decreases the Respiratory Quotient and Reduces Adiposity in Diet-Induced Obese Mice1
Adams, Sean H, Lei, Chunli, Jodka, Carolyn M, Nikoulina, Svetlana E, Hoyt, Julie A, Gedulin, Bronislava, Mack, Christine M, Kendall, Eric S
Published in The Journal of nutrition (01.01.2006)
Published in The Journal of nutrition (01.01.2006)
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Journal Article
In vitro and in vivo characterization of 3-{2-[6-(2-tert-butoxyethoxy)pyridin-3-yl}-1H-imidazol-4-yl}benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist
Elliott, RL, Oliver, RM, Hammond, M, Patterson, TA, She, L, Hargrove, DM, Martin, KA, Maurer, TS, Kalvass, JC, Morgan, BP, DaSilva-Jardine, PA, Stevenson, RW, Mack, CM, Cassella, JV
Published in Journal of medicinal chemistry (27.02.2003)
Published in Journal of medicinal chemistry (27.02.2003)
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Journal Article
Ovarian hormones can organize the rat corpus callosum in adulthood
Bimonte, Heather A., Mack, Christine M., Stavnezer, Amy Jo, Denenberg, Victor H.
Published in Brain research. Developmental brain research (30.06.2000)
Published in Brain research. Developmental brain research (30.06.2000)
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Journal Article
AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENHANCING MOIETIES
SRIVASTAVA VED, LEVY ODILE ESTHER, ROTE WILLIAM E, SAMANT MANOJ P, MACK CHRISTINE M
Year of Publication 04.09.2014
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Year of Publication 04.09.2014
Patent
Hybrid polypeptides with selectable properties
Levy Odile Esther, Soares Christopher J, D'Souza Lawrence J, Lewis Diana Y, Ghosh Soumitra S, Hanley Michael R, Parkes David G, Mack Christine M, Jodka Carolyn M
Year of Publication 27.09.2016
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Year of Publication 27.09.2016
Patent