Search Results - "CHRISTIANE AMENDT" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

by Zenke, Frank T, Zimmermann, Astrid, Sirrenberg, Christian, Dahmen, Heike, Kirkin, Vladimir, Pehl, Ulrich, Grombacher, Thomas, Wilm, Claudia, Fuchss, Thomas, Amendt, Christiane, Vassilev, Lyubomir T, Blaukat, Andree
Published in Molecular cancer therapeutics (01.05.2020)

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Peposertib, a DNA-PK Inhibitor, Enhances the Anti-Tumor Efficacy of Topoisomerase II Inhibitors in Triple-Negative Breast Cancer Models

Peposertib, a DNA-PK Inhibitor, Enhances the Anti-Tumor Efficacy of Topoisomerase II Inhibitors in Triple-Negative Breast Cancer Models

by Revia, Steffie, Neumann, Felix, Jabs, Julia, Orio, Florian, Sirrenberg, Christian, Zimmermann, Astrid, Amendt, Christiane, Albers, Joachim
Published in International journal of molecular sciences (08.05.2024)

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DNA-Dependent Protein Kinase Inhibitor Peposertib Potentiates the Cytotoxicity of Topoisomerase II Inhibitors in Synovial Sarcoma Models

DNA-Dependent Protein Kinase Inhibitor Peposertib Potentiates the Cytotoxicity of Topoisomerase II Inhibitors in Synovial Sarcoma Models

by Revia, Steffie, Budzinska, Magdalena A, Bogatyrova, Olga, Neumann, Felix, Zimmermann, Astrid, Amendt, Christiane, Albers, Joachim
Published in Cancers (30.12.2023)

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Association of EGFR Expression Level and Cetuximab Activity in Patient-Derived Xenograft Models of Human Non-Small Cell Lung Cancer

Association of EGFR Expression Level and Cetuximab Activity in Patient-Derived Xenograft Models of Human Non-Small Cell Lung Cancer

by AMENDT, Christiane, STAUB, Eike, FRIESE-HAMIM, Manja, STÖRKEL, Stephan, STROH, Christopher
Published in Clinical cancer research (01.09.2014)

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Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate

by Orth, James D, Tang, Yangzhong, Shi, Jade, Loy, Clement T, Amendt, Christiane, Wilm, Claudia, Zenke, Frank T, Mitchison, Timothy J
Published in Molecular cancer therapeutics (01.11.2008)

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Matuzumab Short-Term Therapy in Experimental Pancreatic Cancer: Prolonged Antitumor Activity in Combination with Gemcitabine

Matuzumab Short-Term Therapy in Experimental Pancreatic Cancer: Prolonged Antitumor Activity in Combination with Gemcitabine

by KLEESPIES, Axel, ISCHENKO, Ivan, EICHHORN, Martin E, SEELIGER, Hendrik, AMENDT, Christiane, MANTELL, Ole, JAUCH, Karl-Walter, BRUNS, Christiane J
Published in Clinical cancer research (01.09.2008)

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IgG1 anti‐epidermal growth factor receptor antibodies induce CD8‐dependent antitumor activity

IgG1 anti‐epidermal growth factor receptor antibodies induce CD8‐dependent antitumor activity

by Kubach, Jan, Hubo, Mario, Amendt, Christiane, Stroh, Christopher, Jonuleit, Helmut
Published in International journal of cancer (15.02.2015)

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Abstract 2362: Preclinical efficacy and safety of M9140, a novel antibody-drug conjugate (ADC) with topoisomerase 1 (TOP1) inhibitor payload targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)-expressing colorectal tumors

Abstract 2362: Preclinical efficacy and safety of M9140, a novel antibody-drug conjugate (ADC) with topoisomerase 1 (TOP1) inhibitor payload targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)-expressing colorectal tumors

by Raab-Westphal, Sabine, Hart, Felix, Sloot, Willem, Shan, Min, Rasche, Nicolas, Amendt, Christiane, Anderl, Jan
Published in Cancer research (Chicago, Ill.) (22.03.2024)

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Abstract 964: Induction of immunogenic cell death and interferon signaling by carboplatin and the ATR inhibitor M6620 may contribute to anti-tumor activity of M6620-carboplatin-avelumab triplet combination in MC38 tumor model

Abstract 964: Induction of immunogenic cell death and interferon signaling by carboplatin and the ATR inhibitor M6620 may contribute to anti-tumor activity of M6620-carboplatin-avelumab triplet combination in MC38 tumor model

by Alimzhanov, Marat, George, Ashwin, Shah, Parantu, Zimmerman, Astrid, Schroeder, Andreas, Falk, Martin, Amendt, Christiane, Halle, Joern-Peter, Blaukat, Andree, Zenke, Frank, Soulard, Patricia
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Abstract 2269: ATR inhibitor M6620 enhances anti-tumor efficacy of the combination of the anti-PD-L1 antibody avelumab with platinum-based chemotherapy

Abstract 2269: ATR inhibitor M6620 enhances anti-tumor efficacy of the combination of the anti-PD-L1 antibody avelumab with platinum-based chemotherapy

by Alimzhanov, Marat, Soulard, Patricia, Zimmermann, Astrid, Schroeder, Andreas, Mehr, Keyvan Tadjalli, Amendt, Christiane, Sim, Geok Choo, Blaukat, Andree, Halle, Joern-Peter, Zenke, Frank T.
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Abstract ND08: M3554, a novel anti-GD2 antibody drug conjugate

Abstract ND08: M3554, a novel anti-GD2 antibody drug conjugate

by Amendt, Christiane, Knuehl, Christine, Crandall, Timothy, Sloot, Willem, Toister-Achituv, Mira, Sweeney-Lasch, Stanley, Pereira, Joao NS, Dotterweich, Julia, Boehm, Hans_Henning, Ma, Jianguo, Anderl, Jan
Published in Cancer research (Chicago, Ill.) (05.04.2024)

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Tumor Static Concentration Curves in Combination Therapy

Tumor Static Concentration Curves in Combination Therapy

by Cardilin, Tim, Almquist, Joachim, Jirstrand, Mats, Sostelly, Alexandre, Amendt, Christiane, El Bawab, Samer, Gabrielsson, Johan
Published in The AAPS journal (01.03.2017)

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Erratum to: Tumor Static Concentration Curves in Combination Therapy

Erratum to: Tumor Static Concentration Curves in Combination Therapy

by Cardilin, Tim, Almquist, Joachim, Jirstand, Mats, Soselly, Alexandre, Amendt, Christiane, El Bawab, Samer, Gabrielsson, Johan
Published in The AAPS journal (01.03.2017)

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The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

by SCHIEMANN, Kai, FINSINGER, Dirk, ZENKE, Frank, AMENDT, Christiane, KNÖCHEL, Thorsten, BRUGE, David, BUCHSTALLER, Hans-Peter, EMDE, Ulrich, STÄHLE, Wolfgang, ANZALI, Soheila
Published in Bioorganic & medicinal chemistry letters (01.03.2010)

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Abstract 5423: Translational PK/PD/efficacy modeling and efficacious human dose prediction for a first-in-class MUC1-EGFR (M1231) bispecific antibody drug conjugate

Abstract 5423: Translational PK/PD/efficacy modeling and efficacious human dose prediction for a first-in-class MUC1-EGFR (M1231) bispecific antibody drug conjugate

by Zutshi, Anup, Neuteboom, Berend, Kumar, Seema, Sloot, Willem, Knuehl, Christine, Dotterweich, Julia, Ma, Jianguo, Amendt, Christiane, Venkatakrishnan, Karthik, Park, Taeshin, Pappas, John, Kim, Kyoung-Ae
Published in Cancer research (Chicago, Ill.) (15.06.2022)

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Abstract 5284: M1231 is a bispecific anti-MUC1xEGFR antibody-drug conjugate designed to treat solid tumors with MUC1 and EGFR co-expression

Abstract 5284: M1231 is a bispecific anti-MUC1xEGFR antibody-drug conjugate designed to treat solid tumors with MUC1 and EGFR co-expression

by Knuehl, Christine, Toleikis, Lars, Dotterweich, Julia, Ma, Jianguo, Kumar, Seema, Ross, Edith, Wilm, Claudia, Schmitt, Martina, Grote, Hans Juergen, Amendt, Christiane
Published in Cancer research (Chicago, Ill.) (15.06.2022)

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The Serum Protein α2-HS Glycoprotein/Fetuin Inhibits Apatite Formation in Vitro and in Mineralizing Calvaria Cells

The Serum Protein α2-HS Glycoprotein/Fetuin Inhibits Apatite Formation in Vitro and in Mineralizing Calvaria Cells

by Schinke, Thorsten, Amendt, Christiane, Trindl, Andreas, Pöschke, Oliver, Müller-Esterl, Werner, Jahnen-Dechent, Willi
Published in The Journal of biological chemistry (01.08.1996)

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Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors

Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors

by Buchstaller, Hans-Peter, Burgdorf, Lars, Finsinger, Dirk, Stieber, Frank, Sirrenberg, Christian, Amendt, Christiane, Grell, Matthias, Zenke, Frank, Krier, Mireille
Published in Bioorganic & medicinal chemistry letters (15.04.2011)

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Abstract 2639: Discovery of novel small molecule inhibitors of Hsp90 for oral treatment

Abstract 2639: Discovery of novel small molecule inhibitors of Hsp90 for oral treatment

by Sirrenberg, Christian, Eggenweiler, Hans-Michael, Buchstaller, Hans-Peter, Wolf, Michael, Grädler, Ulrich, Musil, Djordje, Hoppe, Edmund, Zimmermann, Astrid, Amendt, Christiane, Schwartz, Harry, März, Joachim, Bomke, Jörg, Ansgar, Wegener, Gleitz, Johannes
Published in Cancer research (Chicago, Ill.) (15.04.2010)

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The discovery and optimization of hexahydro-2 H-pyrano[3,2- c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

The discovery and optimization of hexahydro-2 H-pyrano[3,2- c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5

by Schiemann, Kai, Finsinger, Dirk, Zenke, Frank, Amendt, Christiane, Knöchel, Thorsten, Bruge, David, Buchstaller, Hans-Peter, Emde, Ulrich, Stähle, Wolfgang, Anzali, Soheila
Published in Bioorganic & medicinal chemistry letters (2010)

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