Search Results - "CHRISTIAN GEGE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

by Mayr, Fabian, Möller, Gabriele, Garscha, Ulrike, Fischer, Jana, Rodríguez Castaño, Patricia, Inderbinen, Silvia G, Temml, Veronika, Waltenberger, Birgit, Schwaiger, Stefan, Hartmann, Rolf W, Gege, Christian, Martens, Stefan, Odermatt, Alex, Pandey, Amit V, Werz, Oliver, Adamski, Jerzy, Stuppner, Hermann, Schuster, Daniela
Published in International journal of molecular sciences (01.10.2020)

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Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently?

Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently?

by Gege, Christian
Published in Expert opinion on drug discovery (02.12.2021)

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Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion

Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion

by Kav, Batuhan, Demé, Bruno, Gege, Christian, Tanaka, Motomu, Schneck, Emanuel, Weikl, Thomas R.
Published in Frontiers in molecular biosciences (19.11.2021)

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RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345

RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345

by Gege, Christian
Published in Expert opinion on therapeutic patents (02.01.2017)

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Replacement of sulfonamide by sulfoximine within a helicase-primase inhibitor with restricted flexibility

Replacement of sulfonamide by sulfoximine within a helicase-primase inhibitor with restricted flexibility

by Gege, Christian, Kleymann, Gerald
Published in Bioorganic & medicinal chemistry letters (01.07.2024)

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Retinoid-related orphan receptor gamma t (RORγt) inhibitors from Vitae Pharmaceuticals (WO2015116904) and structure proposal for their Phase I candidate VTP-43742

Retinoid-related orphan receptor gamma t (RORγt) inhibitors from Vitae Pharmaceuticals (WO2015116904) and structure proposal for their Phase I candidate VTP-43742

by Gege, Christian
Published in Expert opinion on therapeutic patents (02.06.2016)

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Helicase-primase inhibitors for the treatment of herpes simplex virus infections - patent evaluation of WO2023/225162 from Gilead Sciences Inc

Helicase-primase inhibitors for the treatment of herpes simplex virus infections - patent evaluation of WO2023/225162 from Gilead Sciences Inc

by Gege, Christian, Kleymann, Gerald
Published in Expert opinion on therapeutic patents (02.10.2024)

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Retinoid-related orphan receptor γ t modulators: comparison of Glenmark's me-too patent application (WO2015008234) with the originator application from Merck Sharp and Dohme (WO2012106995)

Retinoid-related orphan receptor γ t modulators: comparison of Glenmark's me-too patent application (WO2015008234) with the originator application from Merck Sharp and Dohme (WO2012106995)

by Gege, Christian
Published in Expert opinion on therapeutic patents (03.10.2015)

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Carbohydrate−Carbohydrate Recognition Between Lewis X Blood Group Antigens, Mediated by Calcium Ions

Carbohydrate−Carbohydrate Recognition Between Lewis X Blood Group Antigens, Mediated by Calcium Ions

by Gege, Christian, Geyer, Armin, Schmidt, Richard R.
Published in European journal of organic chemistry (01.08.2002)

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New developments in celiac disease treatments

New developments in celiac disease treatments

by Buriánek, Franziska, Gege, Christian, Marinković, Petar
Published in Drug discovery today (01.09.2024)

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Journal Article

Synthesis and Molecular Tumbling Properties of Sialyl Lewis X and Derived Neoglycolipids

Synthesis and Molecular Tumbling Properties of Sialyl Lewis X and Derived Neoglycolipids

by Gege, Christian, Geyer, Armin, Schmidt, Richard R.
Published in Chemistry : a European journal (03.06.2002)

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Nonsteroidal FXR Ligands: Current Status and Clinical Applications

Nonsteroidal FXR Ligands: Current Status and Clinical Applications

by Gege, Christian, Hambruch, Eva, Hambruch, Nina, Kinzel, Olaf, Kremoser, Claus
Published in Handbook of experimental pharmacology (01.01.2019)

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Helicase primase inhibitors (HPIs) are efficacious for therapy of human herpes simplex virus (HSV) disease in an infection mouse model

Helicase primase inhibitors (HPIs) are efficacious for therapy of human herpes simplex virus (HSV) disease in an infection mouse model

by Uhlig, Nadja, Donner, Anne-Kathrin, Gege, Christian, Lange, Franziska, Kleymann, Gerald, Grunwald, Thomas
Published in Antiviral research (01.11.2021)

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Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities

Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities

by Gege, Christian, Kinzel, Olaf, Steeneck, Christoph, Schulz, Andreas, Kremoser, Claus
Published in Current topics in medicinal chemistry (2014)

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Validation of nuclear receptor RORγ isoform 1 as a novel host-directed antiviral target based on the modulation of cholesterol levels

Validation of nuclear receptor RORγ isoform 1 as a novel host-directed antiviral target based on the modulation of cholesterol levels

by Wangen, Christina, Raithel, Andrea, Tillmanns, Julia, Gege, Christian, Herrmann, Alexandra, Vitt, Daniel, Kohlhof, Hella, Marschall, Manfred, Hahn, Friedrich
Published in Antiviral research (01.01.2024)

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Development of a Potent Nurr1 Agonist Tool for In Vivo Applications

Development of a Potent Nurr1 Agonist Tool for In Vivo Applications

by Vietor, Jan, Gege, Christian, Stiller, Tanja, Busch, Romy, Schallmayer, Espen, Kohlhof, Hella, Höfner, Georg, Pabel, Jörg, Marschner, Julian A., Merk, Daniel
Published in Journal of medicinal chemistry (11.05.2023)

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Total synthesis of the natural antigen involved in the hyperacute rejection response to xenotransplants

Total synthesis of the natural antigen involved in the hyperacute rejection response to xenotransplants

by Gege, Christian, Kinzy, Willy, Schmidt, Richard R.
Published in Carbohydrate research (06.10.2000)

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Thermodynamic Properties and Swelling Behavior of Glycolipid Monolayers at Interfaces

Thermodynamic Properties and Swelling Behavior of Glycolipid Monolayers at Interfaces

by Schneider, Matthias F, Mathe, Gerald, Tanaka, Motomu, Schmidt, Richard R
Published in The journal of physical chemistry. B (07.06.2001)

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Identification of the first inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORβ and RORγt

Identification of the first inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORβ and RORγt

by Gege, Christian, Schlüter, Thomas, Hoffmann, Thomas
Published in Bioorganic & medicinal chemistry letters (15.11.2014)

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Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

by Steuer, Christian, Gege, Christian, Fischl, Wolfgang, Heinonen, Karl H., Bartenschlager, Ralf, Klein, Christian D.
Published in Bioorganic & medicinal chemistry (01.07.2011)

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