Macrophage-colony stimulating factor is required for the production of neutrophil-promoting activity by mouse embryo fibroblasts deficient in G-CSF and GM-CSF
Zhang, Hui Hua, Basu, Sunanda, Wu, Fenqiang, Begley, C. Glenn, Saris, Christiaan J. M., Dunn, Ashley R., Burgess, Antony W., Walker, Francesca
Published in Journal of leukocyte biology (01.10.2007)
Published in Journal of leukocyte biology (01.10.2007)
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Part 2: Structure–activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase
Wurz, Ryan P., Pettus, Liping H., Henkle, Bradley, Sherman, Lisa, Plant, Matthew, Miner, Kent, McBride, Helen J., Wong, Lu Min, Saris, Christiaan J.M., Lee, Matthew R., Chmait, Samer, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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3-Amino-7-phthalazinylbenzoisoxazoles as a Novel Class of Potent, Selective, and Orally Available Inhibitors of p38α Mitogen-Activated Protein Kinase
Pettus, Liping H, Xu, Shimin, Cao, Guo-Qiang, Chakrabarti, Partha P, Rzasa, Robert M, Sham, Kelvin, Wurz, Ryan P, Zhang, Dawei, Middleton, Scott, Henkle, Bradley, Plant, Matthew H, Saris, Christiaan J. M, Sherman, Lisa, Wong, Lu Min, Powers, David A, Tudor, Yanyan, Yu, Violeta, Lee, Matthew R, Syed, Rashid, Hsieh, Faye, Tasker, Andrew S
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase ⊥ Atomic coordinates and structure factors for crystal structure of compound 3d with p38α can be accessed using PDB code 3LHJ
Pettus, Liping H, Wurz, Ryan P, Xu, Shimin, Herberich, Brad, Henkle, Bradley, Liu, Qiurong, McBride, Helen J, Mu, Sharon, Plant, Matthew H, Saris, Christiaan J. M, Sherman, Lisa, Wong, Lu Min, Chmait, Samer, Lee, Matthew R, Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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Independent and inter-dependent immunoregulatory effects of IL-27, IFN-β and IL-10 in the suppression of human Th17 cells and murine EAE
Fitzgerald, Denise C., Fonseca-Kelly, Zoe, Cullimore, Melissa L., Safabakhsh, Pegah, Saris, Christiaan J. M., Zhang, Guang-Xian, Rostami, Abdolmohamad
Published in The Journal of immunology (1950) (01.03.2013)
Published in The Journal of immunology (1950) (01.03.2013)
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Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38 alpha Mitogen-Activated Protein Kinase
Pettus, Liping H., Wurz, Ryan P., Xu, Shimin, Herberich, Brad, Henkle, Bradley, Liu, Qiurong, McBride, Helen J., Mu, Sharon, Plant, Matthew H., Saris, Christiaan J. M., Sherman, Lisa, Wong, Lu Min, Chmait, Samer, Lee, Matthew R., Mohr, Christopher, Hsieh, Faye, Tasker, Andrew S.
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study
van Es, Michael A, MD, Van Vught, Paul W, MSc, Blauw, Hylke M, MD, Franke, Lude, MSc, Saris, Christiaan G, MD, Andersen, Peter M, MD, Van Den Bosch, Ludo, PhD, de Jong, Sonja W, MD, van 't Slot, Ruben, BSc, Birve, Anna, PhD, Lemmens, Robin, MD, de Jong, Vianney, MD, Baas, Frank, PhD, Schelhaas, Helenius J, MD, Sleegers, Kristel, MD, Van Broeckhoven, Christine, PhD, Wokke, John HJ, MD, Wijmenga, Cisca, PhD, Robberecht, Wim, MD, Veldink, Jan H, MD, Ophoff, Roel A, PhD, van den Berg, Leonard H, MD
Published in Lancet neurology (01.10.2007)
Published in Lancet neurology (01.10.2007)
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IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis1
Troy, Amy E., Zaph, Colby, Du, Yurong, Taylor, Betsy C., Guild, Katherine J., Hunter, Christopher A., Saris, Christiaan J. M., Artis, David
Published in The Journal of immunology (1950) (13.07.2009)
Published in The Journal of immunology (1950) (13.07.2009)
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A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes: IL-27 inhibits activation induced T cell death
Kim, Gisen, Shinnakasu, Ryo, Saris, Christiaan JM, Cheroutre, Hilde, Kronenberg, Mitchell
Published in The Journal of immunology (1950) (18.01.2013)
Published in The Journal of immunology (1950) (18.01.2013)
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A Role for IL-27/IL-27R Signaling in Prevention of Acute Intestinal Inflammation (B53)
Troy, Amy E., Saris, Christiaan J M, Hunter, Christopher A, Artis, David
Published in The Journal of immunology (1950) (01.04.2007)
Published in The Journal of immunology (1950) (01.04.2007)
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Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza: e1004110
Liu, Francesca DianeM, Kenngott, Elisabeth E, Schröter, Micha F, Kühl, Anja, Jennrich, Silke, Watzlawick, Ralf, Hoffmann, Ute, Wolff, Thorsten, Norley, Stephen, Scheffold, Alexander, Stumhofer, Jason S, Saris, Christiaan JM, Schwab, Jan M, Hunter, Christopher A, Debes, Gudrun F, Hamann, Alf
Published in PLoS pathogens (01.05.2014)
Published in PLoS pathogens (01.05.2014)
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3-Amino-7-phthalazinylbenzoisoxazoles as a Novel Class of Potent, Selective, and Orally Available Inhibitors of p38a Mitogen-Activated Protein Kinase
PETTUS, Liping H, SHIMIN XU, PLANT, Matthew H, SARIS, Christiaan J. M, SHERMAN, Lisa, LU MIN WONG, POWERS, David A, TUDOR, Yanyan, YU, Violeta, LEE, Matthew R, SYED, Rashid, HSIEH, Faye, CAO, Guo-Qiang, TASKER, Andrew S, CHAKRABARTI, Partha P, RZASA, Robert M, SHAM, Kelvin, WURZ, Ryan P, DAWEI ZHANG, MIDDLETON, Scott, HENKLE, Bradley
Published in Journal of medicinal chemistry (2008)
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Published in Journal of medicinal chemistry (2008)
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