Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation
Jänne, Pasi A., Riely, Gregory J., Gadgeel, Shirish M., Heist, Rebecca S., Ou, Sai-Hong I., Pacheco, Jose M., Johnson, Melissa L., Sabari, Joshua K., Leventakos, Konstantinos, Yau, Edwin, Bazhenova, Lyudmila, Negrao, Marcelo V., Pennell, Nathan A., Zhang, Jun, Anderes, Kenna, Der-Torossian, Hirak, Kheoh, Thian, Velastegui, Karen, Yan, Xiaohong, Christensen, James G., Chao, Richard C., Spira, Alexander I.
Published in The New England journal of medicine (14.07.2022)
Published in The New England journal of medicine (14.07.2022)
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Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
Yaeger, Rona, Weiss, Jared, Pelster, Meredith S., Spira, Alexander I., Barve, Minal, Ou, Sai-Hong I., Leal, Ticiana A., Bekaii-Saab, Tanios S., Paweletz, Cloud P., Heavey, Grace A., Christensen, James G., Velastegui, Karen, Kheoh, Thian, Der-Torossian, Hirak, Klempner, Samuel J.
Published in The New England journal of medicine (05.01.2023)
Published in The New England journal of medicine (05.01.2023)
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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1)
Ou, Sai-Hong Ignatius, Jänne, Pasi A., Leal, Ticiana A., Rybkin, Igor I., Sabari, Joshua K., Barve, Minal A., Bazhenova, Lyudmila, Johnson, Melissa L., Velastegui, Karen L., Cilliers, Cornelius, Christensen, James G., Yan, Xiaohong, Chao, Richard C., Papadopoulos, Kyriakos P.
Published in Journal of clinical oncology (10.08.2022)
Published in Journal of clinical oncology (10.08.2022)
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Bullying Victimization and Youth's Likelihood of Carrying a Handgun
Christensen, James B, Jones, Melissa S, Hoffmann, John P
Published in Journal of interpersonal violence (09.08.2024)
Published in Journal of interpersonal violence (09.08.2024)
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Lack of association between human plasma oxytocin and interpersonal trust in a Prisoner's Dilemma paradigm
Christensen, James C, Shiyanov, Pavel A, Estepp, Justin R, Schlager, John J
Published in PloS one (30.12.2014)
Published in PloS one (30.12.2014)
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Enhanced efficacy of sitravatinib in metastatic models of antiangiogenic therapy resistance
Dolan, Melissa, Mastri, Michalis, Tracz, Amanda, Christensen, James G, Chatta, Gurkamal, Ebos, John M L
Published in PloS one (01.08.2019)
Published in PloS one (01.08.2019)
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Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
Sequist, Lecia V, Waltman, Belinda A, Dias-Santagata, Dora, Digumarthy, Subba, Turke, Alexa B, Fidias, Panos, Bergethon, Kristin, Shaw, Alice T, Gettinger, Scott, Cosper, Arjola K, Akhavanfard, Sara, Heist, Rebecca S, Temel, Jennifer, Christensen, James G, Wain, John C, Lynch, Thomas J, Vernovsky, Kathy, Mark, Eugene J, Lanuti, Michael, Iafrate, A John, Mino-Kenudson, Mari, Engelman, Jeffrey A
Published in Science translational medicine (23.03.2011)
Published in Science translational medicine (23.03.2011)
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Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer
Kemp, Samantha B, Cheng, Noah, Markosyan, Nune, Sor, Rina, Kim, Il-Kyu, Hallin, Jill, Shoush, Jason, Quinones, Liz, Brown, Natalie V, Bassett, Jared B, Joshi, Nikhil, Yuan, Salina, Smith, Molly, Vostrejs, William P, Perez-Vale, Kia Z, Kahn, Benjamin, Mo, Feiyan, Donahue, Timothy R, Radu, Caius G, Clendenin, Cynthia, Christensen, James G, Vonderheide, Robert H, Stanger, Ben Z
Published in Cancer discovery (06.02.2023)
Published in Cancer discovery (06.02.2023)
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MET Amplification Identifies a Small and Aggressive Subgroup of Esophagogastric Adenocarcinoma With Evidence of Responsiveness to Crizotinib
LENNERZ, Jochen K, KWAK, Eunice L, SALGIA, Ravi, BANG, Yung-Jue, CLARK, Jeffrey W, SOLOMON, Benjamin J, JOHN IAFRATE, A, ACKERMAN, Allison, MICHAEL, Michael, FOX, Stephen B, BERGETHON, Kristin, LAUWERS, Gregory Y, CHRISTENSEN, James G, WILNER, Keith D, HABER, Daniel A
Published in Journal of clinical oncology (20.12.2011)
Published in Journal of clinical oncology (20.12.2011)
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A Novel ALK Secondary Mutation and EGFR Signaling Cause Resistance to ALK Kinase Inhibitors
SASAKI, Takaaki, KOIVUNEN, Jussi, CAPELLETTI, Marzia, SHIMAMURA, Takeshi, ERCAN, Dalia, STUMPFOVA, Magda, YUN XIAO, WEREMOWICZ, Stanislawa, BUTANEY, Mohit, HEON, Stephanie, WILNER, Keith, CHRISTENSEN, James G, OGINO, Atsuko, ECK, Michel J, WONG, Kwok-Kin, LINDEMAN, Neal, GRAY, Nathanael S, RODIG, Scott J, JÄNNE, Pasi A, YANAGITA, Masahiko, NIKIFOROW, Sarah, ZHENG, Wei, LATHAN, Christopher, PAUL MARCOUX, J, JINYAN DU, OKUDA, Katsuhiro
Published in Cancer research (Chicago, Ill.) (15.09.2011)
Published in Cancer research (Chicago, Ill.) (15.09.2011)
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Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer
Sabari, Joshua K, Velcheti, Vamsidhar, Shimizu, Kazuhide, Strickland, Matthew R, Heist, Rebecca S, Singh, Mohini, Nayyar, Naema, Giobbie-Hurder, Anita, Digumarthy, Subba R, Gainor, Justin F, Rajan, Anant P, Nieblas-Bedolla, Edwin, Burns, Aaron C, Hallin, Jill, Olson, Peter, Christensen, James G, Kurz, Sylvia C, Brastianos, Priscilla K, Wakimoto, Hiroaki
Published in Clinical cancer research (02.08.2022)
Published in Clinical cancer research (02.08.2022)
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Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC
Turke, Alexa B., Zejnullahu, Kreshnik, Wu, Yi-Long, Song, Youngchul, Dias-Santagata, Dora, Lifshits, Eugene, Toschi, Luca, Rogers, Andrew, Mok, Tony, Sequist, Lecia, Lindeman, Neal I., Murphy, Carly, Akhavanfard, Sara, Yeap, Beow Y., Xiao, Yun, Capelletti, Marzia, Iafrate, A. John, Lee, Charles, Christensen, James G., Engelman, Jeffrey A., Jänne, Pasi A.
Published in Cancer cell (19.01.2010)
Published in Cancer cell (19.01.2010)
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The MET Receptor Tyrosine Kinase Is a Potential Novel Therapeutic Target for Head and Neck Squamous Cell Carcinoma
SEIWERT, Tanguy Y, JAGADEESWARAN, Ramasamy, MARTIN, Leslie, KRISHNASWAMY, Soundararajan, KLEIN-SZANTO, Andres, CHRISTENSEN, James G, VOKES, Everett E, SALGIA, Ravi, FAORO, Leonardo, JANAMANCHI, Varalakshmi, NALLASURA, Vidya, MOHAMED EL DINALI, YALA, Soheil, KANTETI, Rajani, COHEN, Ezra E. W, LINGEN, Mark W
Published in Cancer research (Chicago, Ill.) (01.04.2009)
Published in Cancer research (Chicago, Ill.) (01.04.2009)
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HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors
Shojaei, Farbod, Lee, Joseph H, Simmons, Brett H, Wong, Anthony, Esparza, Carlos O, Plumlee, Pamela A, Feng, Junli, Stewart, Albert E, Hu-Lowe, Dana D, Christensen, James G
Published in Cancer research (Chicago, Ill.) (15.12.2010)
Published in Cancer research (Chicago, Ill.) (15.12.2010)
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HGF Rescues Colorectal Cancer Cells from EGFR Inhibition via MET Activation
LISKA, David, CHEN, Chin-Tung, BACHLEITNER-HOFMANN, Thomas, CHRISTENSEN, James G, WEISER, Martin R
Published in Clinical cancer research (01.02.2011)
Published in Clinical cancer research (01.02.2011)
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