Abstract 858: Potent in vivo activity of the aurora kinase inhibitor ABT-348 in human acute myeloid leukemia and myelodysplastic syndrome xenograft models
Wang, Yi-Chun, Kaleta, Lance, Rodriguez, Luis E., Ellis, Paul A., Bukofzer, Gail, Clarin, Jerry, Schlessinger, Sally, Li, Junling, Glaser, Keith, Michaelides, Michael, Albert, Daniel, Tse, Chris, Palma, Joann P., Donawho, Cherrie K.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract B231: Potent in vivo activity of the Aurora kinase inhibitor ABT-348 in a broad spectrum of histological types: Evaluation of efficacy, dosing/scheduling, and PK/PD
Donawho, Cherrie K., Montgomery, Debra, Rodriguez, Luis E., Wang, Yi-Chun, Ellis, Paul E., Kaleta, Lance, Bukofzer, Gail, Bouska, Jennifer, Clarin, Jerry, Schlessinger, Sally, Wang, Baole, Glaser, Keith, Michaelides, Mike, Albert, Daniel, Tse, Chris, Frost, David J., Palma, Joann P.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract 1818: The Aurora B inhibitor ABT-348 is not susceptible to known resistance mechanisms of other Aurora B inhibitors
Guo, Jun, Curtin, Michael L., Heyman, Robin, Anderson, Mark G., Marcotte, Patrick A., Tapang, Paul, Palma, Joann, Rodriguez, Luis E., Niquette, Amanda, Bouska, Jennifer J., Albert, Daniel H., Donawho, Cherrie K., Frey, Robin R., Michaelides, Michael, Tse, Chris, Glaser, Keith B., Shah, Omar J.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract C202: Discovery and initial characterization of the clinical compound ABT-348, a potent inhibitor of the VEGF, PDGF, and Aurora kinase families
Curtin, Michael L., Heyman, Robin, Frey, Robin R., Soni, Niru B., Marcotte, Patick A., Pease, Lori J., Glaser, Keith B., Magoc, Terrance J., Tapang, Paul, Albert, Daniel H., Osterling, Donald J., Olson, Amanda M., Bouska, Jennifer J., Guan, Zhiwen, Martin, Ruth L., Stewart, Kent D., Tse, Chris, Davidsen, Steven K., Michaelides, Michael R.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract A239: Preclinical characterization of ABT-348, a kinase inhibitor targeting the Aurora, VEGFR/PDGFR, and SRC kinase families
Glaser, Keith B., Li, Junling, Marcotte, Patrick A., Magoc, Terrance J., Guo, Jun, Reuter, David R., Tapang, Paul, Wei, Ru-Qi, Pease, Lori J., Bui, Mai H., Chen, Zehan, Frey, Robin R., Johnson, Eric F., Osterling, Donald J., Olson, Amanda M., Bouska, Jennifer J., Curtin, Michael L., Donawho, Cherrie K., Michaelides, Michael R., Tse, Chris, Davidsen, Steven K., Albert, Daniel H.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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NAMPT AND ROCK INHIBITORS
ANIL VASUDEVAN, MACK HELMUT, CHRIS TSE, MICHAEL L CURTIN, MICHAEL MICHAELIDES, RAMZI SWEIS, TODD M HANSEN, MARINA A PLIUSHCHEV, OMAR J SHAH, HOWARD R HEYMAN, CLARK RICHARD F, KEVIN R WOLLER, BRYAN K SORENSEN
Year of Publication 03.08.2017
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Year of Publication 03.08.2017
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Discovery of a Potent and Selective BCL-X L Inhibitor with in Vivo Activity
Tao, Zhi-Fu, Hasvold, Lisa, Wang, Le, Wang, Xilu, Petros, Andrew M., Park, Chang H., Boghaert, Erwin R., Catron, Nathaniel D., Chen, Jun, Colman, Peter M., Czabotar, Peter E., Deshayes, Kurt, Fairbrother, Wayne J., Flygare, John A., Hymowitz, Sarah G., Jin, Sha, Judge, Russell A., Koehler, Michael F. T., Kovar, Peter J., Lessene, Guillaume, Mitten, Michael J., Ndubaku, Chudi O., Nimmer, Paul, Purkey, Hans E., Oleksijew, Anatol, Phillips, Darren C., Sleebs, Brad E., Smith, Brian J., Smith, Morey L., Tahir, Stephen K., Watson, Keith G., Xiao, Yu, Xue, John, Zhang, Haichao, Zobel, Kerry, Rosenberg, Saul H., Tse, Chris, Leverson, Joel D., Elmore, Steven W., Souers, Andrew J.
Published in ACS medicinal chemistry letters (09.10.2014)
Published in ACS medicinal chemistry letters (09.10.2014)
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Bcl-2 Family Protein Inhibitors Induce a Unique Thrombocytopenia In Vivo
Elmore, Steven W., Bauch, Joy, Fryer, Ryan M., Iciek, Laurie, Marsh, Kennan, Morgan, Sherry J., Nelson, Richard, Reinhart, Glenn A., Smith, Morey L., Tse, Chris, Rosenberg, Saul H.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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The Bcl-2 Family Protein Inhibitor, ABT-263, Promotes Apoptotic-Like Response in Isolated Platelets
Tse, Chris, Zhang, Haichao, Chen, Jun, Fryer, Ryan M., Nelson, Richard, Nimmer, Paul, Reinhart, Glenn A., Smith, Morey L., Tahir, Stephen K., Rosenberg, Saul H., Elmore, Steven W.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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The Bcl-2/Bcl-X(L)/Bcl-w inhibitor, navitoclax, enhances the activity of chemotherapeutic agents in vitro and in vivo
Chen, Jun, Jin, Sha, Abraham, Vivek, Huang, Xiaoli, Liu, Bernard, Mitten, Michael J, Nimmer, Paul, Lin, Xiaoyu, Smith, Morey, Shen, Yu, Shoemaker, Alexander R, Tahir, Stephen K, Zhang, Haichao, Ackler, Scott L, Rosenberg, Saul H, Maecker, Heather, Sampath, Deepak, Leverson, Joel D, Tse, Chris, Elmore, Steven W
Published in Molecular cancer therapeutics (01.12.2011)
Published in Molecular cancer therapeutics (01.12.2011)
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NAMPT And Rock Inhibitors
CURTIN, Michael L, HEYMAN, Howard R, WOLLER, Kevin R, SHAH, Omar J, SWEIS, Ramzi, VASUDEVAN, Anil, SORENSEN, Bryan K, HANSEN, Todd M, CLARK, Richard F, PLIUSHCHEV, Marina A, MICHAELIDES, Michael, TSE, Chris, MACK, Helmut
Year of Publication 27.11.2020
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Year of Publication 27.11.2020
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inibidores de nampt e rock
MARINA A. PLIUSHCHEV, ANIL VASUDEVAN, RICHARD F. CLARK, TODD .M HANSEN, OMAR J. SHAH, CHRIS TSE, HOWARD R. HEYMAN, MICHAEL L. CURTIN, MICHAEL MICHAELIDES, HELMUT MACK, RAMZI SWEIS, BRYAN K. SORENSEN, KEVIN R. WOLLER
Year of Publication 24.09.2019
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Year of Publication 24.09.2019
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NAMPT and ROCK inhibitors
Tse, Chris, Michaelides, Michael, Shah, Omar J, Heyman, Howard R, Clark, Rick F, Mack, Helmut, Vasudevan, Anil, Sorensen, Bryan K, Sweis, Ramzi, Hansen, Todd M, Woller, Kevin R, Curtain, Michael L, Pliushchev, Marina A
Year of Publication 09.10.2018
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Year of Publication 09.10.2018
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