Pharmacological effects of berberine and its derivatives: a patent update
Jin, Yifeng, Khadka, Daulat B, Cho, Won-Jea
Published in Expert opinion on therapeutic patents (01.02.2016)
Published in Expert opinion on therapeutic patents (01.02.2016)
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Journal Article
Repurposing of cyclophilin A inhibitors as broad-spectrum antiviral agents
Han, Jinhe, Lee, Myoung Kyu, Jang, Yejin, Cho, Won-Jea, Kim, Meeheyin
Published in Drug discovery today (01.07.2022)
Published in Drug discovery today (01.07.2022)
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Journal Article
Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP
YONG DEUK KIM, PARK, Keun-Gyu, LEE, Chul-Ho, CHOI, Hueng-Sik, LEE, Yong-Soo, PARK, Yun-Yong, KIM, Don-Kyu, NEDUMARAN, Balachandar, WON GU JANG, CHO, Won-Jea, HA, Joohun, LEE, In-Kyu
Published in Diabetes (New York, N.Y.) (01.02.2008)
Published in Diabetes (New York, N.Y.) (01.02.2008)
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Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity
Kim, Jeong-Kook, Kim, Joon-Young, Kim, Han-Jong, Park, Keun-Gyu, Harris, Robert A, Cho, Won-Jea, Lee, Jae-Tae, Lee, In-Kyu
Published in PloS one (15.11.2013)
Published in PloS one (15.11.2013)
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Journal Article
Antiviral Activity of Isoquinolone Derivatives against Influenza Viruses and Their Cytotoxicity
Jang, Yejin, Han, Jinhe, Li, Xiaoli, Shin, Hyunjin, Cho, Won-Jea, Kim, Meehyein
Published in Pharmaceuticals (Basel, Switzerland) (06.07.2021)
Published in Pharmaceuticals (Basel, Switzerland) (06.07.2021)
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Journal Article
Berberine bioisostere Q8 compound stimulates osteoblast differentiation and function in vitro
Han, Younho, Jin, Yifeng, Lee, Sung Ho, Khadka, Daulat Bikram, Cho, Won-Jea, Lee, Kwang Youl
Published in Pharmacological research (01.05.2017)
Published in Pharmacological research (01.05.2017)
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Journal Article
Insights into the Structural Features Essential for JAK2 Inhibition and Selectivity
Zhao, Chao, Khadka, Daulat Bikram, Cho, Won-Jea
Published in Current medicinal chemistry (01.04.2016)
Published in Current medicinal chemistry (01.04.2016)
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Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines
Karki, Radha, Thapa, Pritam, Kang, Mi Jeong, Jeong, Tae Cheon, Nam, Jung Min, Kim, Hye-Lin, Na, Younghwa, Cho, Won-Jea, Kwon, Youngjoo, Lee, Eung-Seok
Published in Bioorganic & medicinal chemistry (01.05.2010)
Published in Bioorganic & medicinal chemistry (01.05.2010)
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Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study
Karki, Radha, Thapa, Pritam, Yoo, Han Young, Kadayat, Tara Man, Park, Pil-Hoon, Na, Youngwha, Lee, Eunyoung, Jeon, Kyung-Hwa, Cho, Won-Jea, Choi, Heesung, Kwon, Youngjoo, Lee, Eung-Seok
Published in European journal of medicinal chemistry (01.03.2012)
Published in European journal of medicinal chemistry (01.03.2012)
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Journal Article
Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety
Thapa, Pritam, Karki, Radha, Yun, Minho, Kadayat, Tara Man, Lee, Eunyoung, Kwon, Han Byeol, Na, Younghwa, Cho, Won-Jea, Kim, Nam Doo, Jeong, Byeong-Seon, Kwon, Youngjoo, Lee, Eung-Seok
Published in European journal of medicinal chemistry (01.06.2012)
Published in European journal of medicinal chemistry (01.06.2012)
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cAMP‐dependent activation of protein kinase A as a therapeutic target of skin hyperpigmentation by diphenylmethylene hydrazinecarbothioamide
Shin, Hyoeun, Hong, Seung Deok, Roh, Eunmiri, Jung, Sang‐Hun, Cho, Won‐Jea, Hong Park, Sun, Yoon, Da Young, Ko, Seon Mi, Hwang, Bang Yeon, Hong, Jin Tae, Heo, Tae‐Young, Han, Sang‐Bae, Kim, Youngsoo
Published in British journal of pharmacology (01.07.2015)
Published in British journal of pharmacology (01.07.2015)
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The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3
Lee, Sun-Mi, Yoon, Kyoung Bin, Lee, Hyo Jeong, Kim, Jiwon, Chung, You Kyoung, Cho, Won-Jea, Mukai, Chisato, Choi, Sun, Kang, Keon Wook, Han, Sun-Young, Ko, Hyojin, Kim, Yong-Chul
Published in Bioorganic & medicinal chemistry (01.11.2016)
Published in Bioorganic & medicinal chemistry (01.11.2016)
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Journal Article
Structure-based Virtual Screening and Identification of a Novel Androgen Receptor Antagonist
Song, Chin-Hee, Yang, Su Hui, Park, Eunsook, Cho, Suk Hee, Gong, Eun-Yeung, Khadka, Daulat Bikram, Cho, Won-Jea, Lee, Keesook
Published in The Journal of biological chemistry (31.08.2012)
Published in The Journal of biological chemistry (31.08.2012)
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Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis
Kim, Eun-Jin, Yoon, Young-Sil, Hong, Suckchang, Son, Ho-Young, Na, Tae-Young, Lee, Min-Ho, Kang, Hyun-Jin, Park, Jinyoung, Cho, Won-Jea, Kim, Sang-Gun, Koo, Seung-Hoi, Park, Hyeung-geun, Lee, Mi-Ock
Published in Hepatology (Baltimore, Md.) (01.05.2012)
Published in Hepatology (Baltimore, Md.) (01.05.2012)
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Journal Article
Crystal Structure of Human Myotubularin-Related Protein 1 Provides Insight into the Structural Basis of Substrate Specificity
Bong, Seoung Min, Son, Kka-bi, Yang, Seung-Won, Park, Jae-Won, Cho, Jea-Won, Kim, Kyung-Tae, Kim, Hackyoung, Kim, Seung Jun, Kim, Young Jun, Lee, Byung Il
Published in PloS one (28.03.2016)
Published in PloS one (28.03.2016)
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Journal Article
SAR Based Design of Nicotinamides as a Novel Class of Androgen Receptor Antagonists for Prostate Cancer
Yang, Su Hui, Song, Chin-Hee, Van, Hue Thi My, Park, Eunsook, Khadka, Daulat Bikram, Gong, Eun-Yeung, Lee, Keesook, Cho, Won-Jea
Published in Journal of medicinal chemistry (25.04.2013)
Published in Journal of medicinal chemistry (25.04.2013)
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Journal Article
Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode
Lee, Sang Jae, Han, Byeong-Gu, Cho, Jea-Won, Choi, Jang-Sik, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Lee, Byung Il
Published in PloS one (31.07.2013)
Published in PloS one (31.07.2013)
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Journal Article
Development of kNN QSAR Models for 3-Arylisoquinoline Antitumor Agents
Tropsha, Alexander, Golbraikh, Alexander, Cho, Won-Jea
Published in Bulletin of the Korean Chemical Society (20.07.2011)
Published in Bulletin of the Korean Chemical Society (20.07.2011)
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