Definition and dynamic control of a continuous chromatography process independent of cell culture titer and impurities
Chmielowski, Rebecca A., Mathiasson, Linda, Blom, Hans, Go, Daniel, Ehring, Hanno, Khan, Heera, Li, Hong, Cutler, Collette, Lacki, Karol, Tugcu, Nihal, Roush, David
Published in Journal of Chromatography A (01.12.2017)
Published in Journal of Chromatography A (01.12.2017)
Get full text
Journal Article
Athero-inflammatory nanotherapeutics: Ferulic acid-based poly(anhydride-ester) nanoparticles attenuate foam cell formation by regulating macrophage lipogenesis and reactive oxygen species generation
Chmielowski, Rebecca A., Abdelhamid, Dalia S., Faig, Jonathan J., Petersen, Latrisha K., Gardner, Carol R., Uhrich, Kathryn E., Joseph, Laurie B., Moghe, Prabhas V.
Published in Acta biomaterialia (15.07.2017)
Published in Acta biomaterialia (15.07.2017)
Get full text
Journal Article
Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation
Zhao, Nanxia, Yang, Xue, Calvelli, Hannah R, Cao, Yue, Francis, Nicola L, Chmielowski, Rebecca A, Joseph, Laurie B, Pang, Zhiping P, Uhrich, Kathryn E, Baum, Jean, Moghe, Prabhas V
Published in Frontiers in bioengineering and biotechnology (21.02.2020)
Published in Frontiers in bioengineering and biotechnology (21.02.2020)
Get full text
Journal Article
Resolution of heterogeneous charged antibody aggregates via multimodal chromatography: A comparison to conventional approaches
Chmielowski, Rebecca A., Meissner, Sandra, Roush, David, Linden, Thomas O., Glowacki, Edward, Konietzko, Janelle, Nti-Gyabaah, Joseph
Published in Biotechnology progress (01.05.2014)
Published in Biotechnology progress (01.05.2014)
Get full text
Journal Article
Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry
Zhou, Haihong, Hoek, Maarten, Yi, Pan, Rohm, Rory J., Mahsut, Ablatt, Brown, Patricia, Saunders, Jason, Chmielowski, Rebecca A., Ren, Ning, Shuster, Dan, Southwick, Katie, Ayanoglu, Gulesi, Gorman, Dan, Laface, Drake, Santino, Salvatore, Conway, James, Liu, Zhong, Cully, Doris, Cleary, Michele, Roddy, Thomas P., Blom, Daniel
Published in Rapid communications in mass spectrometry (15.12.2013)
Published in Rapid communications in mass spectrometry (15.12.2013)
Get full text
Journal Article
Nanotherapeutics Containing Lithocholic Acid-Based Amphiphilic Scorpion-Like Macromolecules Reduce In Vitro Inflammation in Macrophages: Implications for Atherosclerosis
Moretti, Alysha, Li, Qi, Chmielowski, Rebecca, Joseph, Laurie B, Moghe, Prabhas V, Uhrich, Kathryn E
Published in Nanomaterials (Basel, Switzerland) (02.02.2018)
Published in Nanomaterials (Basel, Switzerland) (02.02.2018)
Get full text
Journal Article
Insulin purification—Innovation continuum via synthesis of fundamentals, technology, and modeling
Roush, David, Iammarino, Michael, Chmielowski, Rebecca, Insaidoo, Francis, McCoy, Mark A., Ortigosa, Allison, Rauscher, Michael
Published in Biotechnology and bioengineering (01.08.2024)
Published in Biotechnology and bioengineering (01.08.2024)
Get full text
Journal Article
Quantitative assessment of environmental impact of biologics manufacturing using process mass intensity analysis
Madabhushi, Sri R., Gavin, John, Xu, Sen, Cutler, Collette, Chmielowski, Rebecca, Rayfield, William, Tugcu, Nihal, Chen, Hao
Published in Biotechnology progress (01.11.2018)
Published in Biotechnology progress (01.11.2018)
Get full text
Journal Article
“Build Your Own” ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation
Emmert, Marion H., Bottecchia, Cecilia, Barrientos, Rodell C., Feng, Yinnian, Holland-Moritz, Daniel, Hughes, Gregory J., Lam, Yu-Hong, Regalado, Erik L., Ruccolo, Serge, Sun, Shuwen, Chmielowski, Rebecca, Yang, Cuixian, Lévesque, François, Raymond, Kelly, Haley, Monica
Published in Organic process research & development (16.08.2024)
Published in Organic process research & development (16.08.2024)
Get full text
Journal Article
Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity
Bennett, Neal K, Chmielowski, Rebecca, Abdelhamid, Dalia S, Faig, Jonathan J, Francis, Nicola, Baum, Jean, Pang, Zhiping P, Uhrich, Kathryn E, Moghe, Prabhas V
Published in Biomaterials (01.12.2016)
Published in Biomaterials (01.12.2016)
Get full text
Journal Article
감소된 숙주 세포 단백질 및 증가된 폴리소르베이트-80 안정성을 갖는 항-CTLA4 모노클로날 항체를 포함하는 방법 및 조성물
WELSH JOHN P, CHMIELOWSKI REBECCA A, SHAH DARSHINI, MILLER JUSTIN B, ROUSH DAVID J, INSAIDOO FRANCIS
Year of Publication 26.05.2022
Get full text
Year of Publication 26.05.2022
Patent
METHODS AND COMPOSITIONS COMPRISING AN ANTI-CTLA4 MONOCLONAL ANTIBODY WITH REDUCED HOST CELL PROTEINS AND INCREASED POLYSORBATE-80 STABILITY
CHMIELOWSKI, Rebecca, A, MILLER, Justin, B, ROUSH, David, J, SHAH, Darshini, INSAIDOO, Francis, WELSH, John, P
Year of Publication 31.01.2024
Get full text
Year of Publication 31.01.2024
Patent
METHODS AND COMPOSITIONS COMPRISING AN ANTI-CTLA4 MONOCLONAL ANTIBODY WITH REDUCED HOST CELL PROTEINS AND INCREASED POLYSORBATE-80 STABILITY
Welsh, John P, Insaidoo, Francis K, Shah, Darshini, Miller, Justin B, Chmielowski, Rebecca A, Roush, David J
Year of Publication 11.04.2024
Get full text
Year of Publication 11.04.2024
Patent
METHODS AND COMPOSITIONS COMPRISING AN ANTI-CTLA4 MONOCLONAL ANTIBODY WITH REDUCED HOST CELL PROTEINS AND INCREASED POLYSORBATE-80 STABILITY
CHMIELOWSKI, Rebecca, A, MILLER, Justin, B, ROUSH, David, J, SHAH, Darshini, INSAIDOO, Francis, WELSH, John, P
Year of Publication 03.08.2022
Get full text
Year of Publication 03.08.2022
Patent