Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers
Ogiwara, Hideaki, Takahashi, Kazuaki, Sasaki, Mariko, Kuroda, Takafumi, Yoshida, Hiroshi, Watanabe, Reiko, Maruyama, Ami, Makinoshima, Hideki, Chiwaki, Fumiko, Sasaki, Hiroki, Kato, Tomoyasu, Okamoto, Aikou, Kohno, Takashi
Published in Cancer cell (11.02.2019)
Published in Cancer cell (11.02.2019)
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Aurora kinase blockade drives de novo addiction of cervical squamous cell carcinoma to druggable EGFR signalling
Komatsu, Masayuki, Nakamura, Kanako, Takeda, Takashi, Chiwaki, Fumiko, Banno, Kouji, Aoki, Daisuke, Takeshita, Fumitaka, Sasaki, Hiroki
Published in Oncogene (15.04.2022)
Published in Oncogene (15.04.2022)
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Efficacy of glutathione inhibitors for the treatment of ARID1A-deficient diffuse-type gastric cancers
Sasaki, Mariko, Chiwaki, Fumiko, Kuroda, Takafumi, Komatsu, Masayuki, Matsusaki, Keisuke, Kohno, Takashi, Sasaki, Hiroki, Ogiwara, Hideaki
Published in Biochemical and biophysical research communications (05.02.2020)
Published in Biochemical and biophysical research communications (05.02.2020)
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ARHGAP–RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer
Komatsu, Masayuki, Ichikawa, Hitoshi, Chiwaki, Fumiko, Sakamoto, Hiromi, Komatsuzaki, Rie, Asaumi, Makoto, Tsunoyama, Kazuhisa, Fukagawa, Takeo, Matsushita, Hiromichi, Boku, Narikazu, Matsusaki, Keisuke, Takeshita, Fumitaka, Yoshida, Teruhiko, Sasaki, Hiroki
Published in Oncogene (21.10.2022)
Published in Oncogene (21.10.2022)
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Upregulation of IGF2R evades lysosomal dysfunction-induced apoptosis of cervical cancer cells via transport of cathepsins
Takeda, Takashi, Komatsu, Masayuki, Chiwaki, Fumiko, Komatsuzaki, Rie, Nakamura, Kanako, Tsuji, Kosuke, Kobayashi, Yusuke, Tominaga, Eiichiro, Ono, Masaya, Banno, Kouji, Aoki, Daisuke, Sasaki, Hiroki
Published in Cell death & disease (20.11.2019)
Published in Cell death & disease (20.11.2019)
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Multiple roles of single‐minded 2 in esophageal squamous cell carcinoma and its clinical implications
Tamaoki, Masashi, Komatsuzaki, Rie, Komatsu, Masayuki, Minashi, Keiko, Aoyagi, Kazuhiko, Nishimura, Takao, Chiwaki, Fumiko, Hiroki, Tomoko, Daiko, Hiroyuki, Morishita, Kazuhiro, Sakai, Yoshiharu, Seno, Hiroshi, Chiba, Tsutomu, Muto, Manabu, Yoshida, Teruhiko, Sasaki, Hiroki
Published in Cancer science (01.04.2018)
Published in Cancer science (01.04.2018)
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Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities
Tanaka, Yosuke, Chiwaki, Fumiko, Kojima, Shinya, Kawazu, Masahito, Komatsu, Masayuki, Ueno, Toshihide, Inoue, Satoshi, Sekine, Shigeki, Matsusaki, Keisuke, Matsushita, Hiromichi, Boku, Narikazu, Kanai, Yae, Yatabe, Yasushi, Sasaki, Hiroki, Mano, Hiroyuki
Published in Nature cancer (01.09.2021)
Published in Nature cancer (01.09.2021)
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Lipolysis-stimulated lipoprotein receptor-targeted antibody-drug conjugate demonstrates potent antitumor activity against epithelial ovarian cancer
Kanda, Mizuki, Serada, Satoshi, Hiramatsu, Kosuke, Funauchi, Masashi, Obata, Kengo, Nakagawa, Satoshi, Ohkawara, Tomoharu, Murata, Okinori, Fujimoto, Minoru, Chiwaki, Fumiko, Sasaki, Hiroki, Ueda, Yutaka, Kimura, Tadashi, Naka, Tetsuji
Published in Neoplasia (New York, N.Y.) (01.01.2023)
Published in Neoplasia (New York, N.Y.) (01.01.2023)
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CD24 and CK4 are upregulated by SIM2, and are predictive biomarkers for chemoradiotherapy and surgery in esophageal cancer
Takashima, Kenji, Fujii, Satoshi, Komatsuzaki, Rie, Komatsu, Masayuki, Takahashi, Mari, Kojima, Takashi, Daiko, Hiroyuki, Minashi, Keiko, Chiwaki, Fumiko, Muto, Manabu, Sasaki, Hiroki, Yano, Tomonori
Published in International journal of oncology (01.03.2020)
Published in International journal of oncology (01.03.2020)
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Bacterial SOS Genes mucAB/umuDC Promote Mouse Tumors by Activating Oncogenes Nedd9/Aurkb via a miR-145 Sponge
Tanooka, Hiroshi, Inoue, Ayako, Takahashi, Ryou-U, Tatsumi, Kouichi, Fujikawa, Kazuo, Nagao, Tetsuji, Ishiai, Masamichi, Chiwaki, Fumiko, Aoyagi, Kazuhiko, Sasaki, Hiroki, Ochiya, Takahiro
Published in Molecular cancer research (01.09.2020)
Published in Molecular cancer research (01.09.2020)
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SIX1 maintains tumor basal cells via transforming growth factor‐β pathway and associates with poor prognosis in esophageal cancer
Nishimura, Takao, Tamaoki, Masashi, Komatsuzaki, Rie, Oue, Naohide, Taniguchi, Hirokazu, Komatsu, Masayuki, Aoyagi, Kazuhiko, Minashi, Keiko, Chiwaki, Fumiko, Shinohara, Hisashi, Tachimori, Yuji, Yasui, Wataru, Muto, Manabu, Yoshida, Teruhiko, Sakai, Yoshiharu, Sasaki, Hiroki
Published in Cancer science (01.02.2017)
Published in Cancer science (01.02.2017)
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Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells
Fujita, Takeshi, Chiwaki, Fumiko, Takahashi, Ryou-u, Aoyagi, Kazuhiko, Yanagihara, Kazuyoshi, Nishimura, Takao, Tamaoki, Masashi, Komatsu, Masayuki, Komatsuzaki, Rie, Matsusaki, Keisuke, Ichikawa, Hitoshi, Sakamoto, Hiromi, Yamada, Yasuhide, Fukagawa, Takeo, Katai, Hitoshi, Konno, Hiroyuki, Ochiya, Takahiro, Yoshida, Teruhiko, Sasaki, Hiroki
Published in PloS one (25.06.2015)
Published in PloS one (25.06.2015)
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SIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma
Nakamura, Kanako, Komatsu, Masayuki, Chiwaki, Fumiko, Takeda, Takashi, Kobayashi, Yusuke, Banno, Kouji, Aoki, Daisuke, Yoshida, Teruhiko, Sasaki, Hiroki
Published in Scientific reports (06.11.2017)
Published in Scientific reports (06.11.2017)
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Response Predictive Markers and Synergistic Agents for Drug Repositioning of Statins in Ovarian Cancer
Kobayashi, Yusuke, Takeda, Takashi, Kunitomi, Haruko, Chiwaki, Fumiko, Komatsu, Masayuki, Nagai, Shimpei, Nogami, Yuya, Tsuji, Kosuke, Masuda, Kenta, Ogiwara, Hideaki, Sasaki, Hiroki, Banno, Kouji, Aoki, Daisuke
Published in Pharmaceuticals (Basel, Switzerland) (21.01.2022)
Published in Pharmaceuticals (Basel, Switzerland) (21.01.2022)
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Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo
Suzuki, Masami, Chiwaki, Fumiko, Sawada, Yumi, Ashikawa, Maho, Aoyagi, Kazuhiko, Fujita, Takeshi, Yanagihara, Kazuyoshi, Komatsu, Masayuki, Narita, Minoru, Suzuki, Tsutomu, Nagase, Hiroshi, Kushima, Ryoji, Sakamoto, Hiromi, Fukagawa, Takeo, Katai, Hitoshi, Nakagama, Hitoshi, Yoshida, Teruhiko, Uezono, Yasuhito, Sasaki, Hiroki
Published in PloS one (08.04.2015)
Published in PloS one (08.04.2015)
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Intraperitoneal delivery of a small interfering RNA targeting NEDD1 prolongs the survival of scirrhous gastric cancer model mice
Fujita, Takeshi, Yanagihara, Kazuyoshi, Takeshita, Fumitaka, Aoyagi, Kazuhiko, Nishimura, Takao, Takigahira, Misato, Chiwaki, Fumiko, Fukagawa, Takeo, Katai, Hitoshi, Ochiya, Takahiro, Sakamoto, Hiromi, Konno, Hiroyuki, Yoshida, Teruhiko, Sasaki, Hiroki
Published in Cancer science (01.02.2013)
Published in Cancer science (01.02.2013)
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Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy
Tanaka, Yosuke, Aoyagi, Kazuhiko, Minashi, Keiko, Komatsuzaki, Rie, Komatsu, Masayuki, Chiwaki, Fumiko, Tamaoki, Masashi, Nishimura, Takao, Takahashi, Naoki, Oda, Ichiro, Tachimori, Yuji, Arao, Tokuzo, Nishio, Kazuto, Kitano, Shigehisa, Narumi, Kenta, Aoki, Kazunori, Fujii, Satoshi, Ochiai, Atsushi, Yoshida, Teruhiko, Muto, Manabu, Yamada, Yasuhide, Sasaki, Hiroki
Published in PloS one (01.12.2015)
Published in PloS one (01.12.2015)
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Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis
Ono, Hiroe, Hiraoka, Nobuyoshi, Lee, Yeon-Su, Woo, Sang Myung, Lee, Woo Jin, Choi, Il Ju, Saito, Akira, Yanagihara, Kazuyoshi, Kanai, Yae, Ohnami, Sumiko, Chiwaki, Fumiko, Sasaki, Hiroki, Sakamoto, Hiromi, Yoshida, Teruhiko, Saeki, Norihisa
Published in Genes chromosomes & cancer (01.01.2012)
Published in Genes chromosomes & cancer (01.01.2012)
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Clinical significance of measurement of plasma annexin V concentration of patients in the emergency room
Matsuda, Ryuko, Kaneko, Noboru, Kikuchi, Migaku, Chiwaki, Fumiko, Toda, Masashi, Ieiri, Tamio, Horikawa, Yoshifumi, Shimizu, Mayumi, Shimamoto, Ken
Published in Resuscitation (01.05.2003)
Published in Resuscitation (01.05.2003)
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Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells
Saeki, Norihisa, Matsuo, Keitaro, Ono, Hiroe, Chihara, Dai, Chiwaki, Fumiko, Yanagihara, Kazuyoshi, Sasaki, Hiroki, Sakamoto, Hiromi, Tanaka, Hideo, Yoshida, Teruhiko
Published in Journal of carcinogenesis (01.01.2013)
Published in Journal of carcinogenesis (01.01.2013)
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