Bifunctional small molecules that mediate the degradation of extracellular proteins
Caianiello, David F., Zhang, Mengwen, Ray, Jason D., Howell, Rebecca A., Swartzel, Jake C., Branham, Emily M. J., Chirkin, Egor, Sabbasani, Venkata R., Gong, Angela Z., McDonald, David M., Muthusamy, Viswanathan, Spiegel, David A.
Published in Nature chemical biology (01.09.2021)
Published in Nature chemical biology (01.09.2021)
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Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation
Gryaznova, Mariya, Burakova, Inna, Smirnova, Yuliya, Morozova, Polina, Chirkin, Egor, Gureev, Artem, Mikhaylov, Evgeny, Korneeva, Olga, Syromyatnikov, Mikhail
Published in Microorganisms (Basel) (30.06.2024)
Published in Microorganisms (Basel) (30.06.2024)
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2-Guanidino-quinazoline promotes the readthrough of nonsense mutations underlying human genetic diseases
Bidou, Laure, Bugaud, Olivier, Merer, Goulven, Coupet, Matthieu, Hatin, Isabelle, Chirkin, Egor, Karri, Sabrina, Cintrat, Jean-Christophe, Namy, Olivier
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
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Journal Article
2-Guanidino-quinazoline promotes the readthrough of nonsense mutations underlying human genetic diseases
Bidou, Laure, Bugaud, Olivier, Merer, Goulven, Coupet, Matthieu, Hatin, Isabelle, Chirkin, Egor, Karri, Sabrina, Demais, Stéphane, François, Pauline, Cintrat, Jean-Christophe, Namy, Olivier
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (30.08.2022)
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Journal Article
Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines
Le Roch, Myriam, Afonso, Damien, Chirkin, Egor, Guillory, Xavier, Porée, François-Hugues
Published in Bioorganic & medicinal chemistry (15.03.2022)
Published in Bioorganic & medicinal chemistry (15.03.2022)
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Journal Article
Viability of a [2 + 2 + 1] Hetero-Pauson–Khand Cycloaddition Strategy toward Securinega Alkaloids: Synthesis of the BCD-Ring Core of Securinine and Related Alkaloids
Chirkin, Egor, Michel, Sylvie, Porée, François-Hugues
Published in Journal of organic chemistry (02.07.2015)
Published in Journal of organic chemistry (02.07.2015)
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Journal Article
The Securinega alkaloids
Chirkin, Eqor, Atkatlian, William, Porée, François-Hugues
Published in The Alkaloids. Chemistry and biology (2015)
Published in The Alkaloids. Chemistry and biology (2015)
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Journal Article
조기 종결 코돈의 억제제로서 퀴나졸린 화합물
NAMY OLIVIER, MERER GOULVEN, BIDOU LAURE, CINTRAT JEAN CHRISTOPHE, CHIRKIN EGOR, BUGAUD OLIVIER
Year of Publication 30.03.2023
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Year of Publication 30.03.2023
Patent
Photochemical Strain‐Release‐Driven Cyclobutylation of C(sp3)‐Centered Radicals
Ernouf, Guillaume, Chirkin, Egor, Rhyman, Lydia, Ramasami, Ponnadurai, Cintrat, Jean‐Christophe
Published in Angewandte Chemie (10.02.2020)
Published in Angewandte Chemie (10.02.2020)
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Journal Article
Neutralization of Pathogenic Fungi with Small‐Molecule Immunotherapeutics
Chirkin, Egor, Muthusamy, Viswanathan, Mann, Paul, Roemer, Terry, Nantermet, Philippe G., Spiegel, David A.
Published in Angewandte Chemie (09.10.2017)
Published in Angewandte Chemie (09.10.2017)
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Journal Article
Chiroptical study and absolute configuration of securinine oxidation products
Chirkin, Egor, Atkatlian, William, Do, Quyên, Gaslonde, Thomas, Dufat, Thi-Hanh, Michel, Sylvie, Lemoine, Pascale, Genta-Jouve, Grégory, Porée, François-Hugues
Published in Natural product research (03.07.2015)
Published in Natural product research (03.07.2015)
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Journal Article
QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS
CINTRAT, Jean-Christophe, MERER, Goulven, BUGARD, Olivier, NAMY, Olivier, CHIRKIN, Egor, BIDOU, Laure
Year of Publication 15.06.2023
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Year of Publication 15.06.2023
Patent
QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS
CINTRAT, Jean-Christophe, MERER, Goulven, NAMY, Olivier, CHIRKIN, Egor, BUGAUD, Olivier, BIDOU, Laure
Year of Publication 22.03.2023
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Year of Publication 22.03.2023
Patent
QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS
CINTRAT, JEANRISTOPHE, BIDOU, LAURE, NAMY, OLIVIER, BUGAUD, OLIVIER, CHIRKIN, EGOR, MERER, GOULVEN
Year of Publication 18.11.2021
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Year of Publication 18.11.2021
Patent
QUINAZOLINE COMPOUNDS AS INHIBITORS OF PREMATURE TERMINATION CODONS
CINTRAT, Jean-Christophe, MERER, Goulven, NAMY, Olivier, CHIRKIN, Egor, BUGAUD, Olivier, BIDOU, Laure
Year of Publication 18.11.2021
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Year of Publication 18.11.2021
Patent