The β-myosin G256E mutation impairs relaxation by altering transducer stiffness
Childers, Matthew C., Kao, Kerry Y., Mohran, Saffie, Regnier, Michael
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin
Rynkiewicz, Michael J, Childers, Matthew C, Karpicheva, Olga E, Regnier, Michael, Geeves, Michael A, Lehman, William
Published in The Journal of general physiology (06.05.2024)
Published in The Journal of general physiology (06.05.2024)
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Journal Article
Insights from molecular dynamics simulations for computational protein design
Childers, Matthew Carter, Daggett, Valerie
Published in Molecular systems design & engineering (01.02.2017)
Published in Molecular systems design & engineering (01.02.2017)
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Journal Article
Embryonic myosin mutations alter the mechanics and maturation of HiPSC derived skeletal muscle
Mandrycky, Christian J., Mohran, Saffie, Childers, Matthew C., Luttrell, Shawn M., Buckingham, Kati, Bamshad, Michael J., Mack, David L., Regnier, Michael
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Dynamics of the Pre-Powerstroke Myosin Lever Arm and the Effects of Omecamtiv Mecarbil
Childers, Matthew Carter, Regnier, Michael
Published in International journal of molecular sciences (01.10.2024)
Published in International journal of molecular sciences (01.10.2024)
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Journal Article
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING
Siu, Tony, Altman, Michael D, Baltus, Gretchen A, Childers, Matthew, Ellis, J. Michael, Gunaydin, Hakan, Hatch, Harold, Ho, Thu, Jewell, James, Lacey, Brian M, Lesburg, Charles A, Pan, Bo-Sheng, Sauvagnat, Berengere, Schroeder, Gottfried K, Xu, Serena
Published in ACS medicinal chemistry letters (10.01.2019)
Published in ACS medicinal chemistry letters (10.01.2019)
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Journal Article
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration
Lee, Soah, Vander Roest, Alison S, Blair, Cheavar A, Kao, Kerry, Bremner, Samantha B, Childers, Matthew C, Pathak, Divya, Heinrich, Paul, Lee, Daniel, Chirikian, Orlando, Mohran, Saffie E, Roberts, Brock, Smith, Jacqueline E, Jahng, James W, Paik, David T, Wu, Joseph C, Gunawardane, Ruwanthi N, Ruppel, Kathleen M, Mack, David L, Pruitt, Beth L, Regnier, Michael, Wu, Sean M, Spudich, James A, Bernstein, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)
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Journal Article
Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts
Landim-Vieira, Maicon, Childers, Matthew C, Wacker, Amanda L, Garcia, Michelle Rodriquez, He, Huan, Singh, Rakesh, Brundage, Elizabeth A, Johnston, Jamie R, Whitson, Bryan A, Chase, P Bryant, Janssen, Paul M L, Regnier, Michael, Biesiadecki, Brandon J, Pinto, J Renato, Parvatiyar, Michelle S
Published in eLife (03.05.2022)
Published in eLife (03.05.2022)
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Journal Article
Novel surveillance of psychological distress during the great recession
Ayers, John W, Althouse, Benjamin M, Allem, Jon-Patrick, Childers, Matthew A, Zafar, Waleed, Latkin, Carl, Ribisl, Kurt M, Brownstein, John S
Published in Journal of affective disorders (15.12.2012)
Published in Journal of affective disorders (15.12.2012)
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Journal Article
Conformational sampling of CMT-2D associated GlyRS mutations
Childers, Matthew Carter, Regnier, Michael, Bothwell, Mark, Smith, Alec S.T.
Published in Brain multiphysics (2022)
Published in Brain multiphysics (2022)
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Journal Article
Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects
Chong, Jessica X., Childers, Matthew Carter, Marvin, Colby T., Marcello, Anthony J., Gonorazky, Hernan, Hazrati, Lili-Naz, Dowling, James J., Al Amrani, Fatema, Alanay, Yasemin, Nieto, Yolanda, Gabriel, Miguel Á Marín, Aylsworth, Arthur S., Buckingham, Kati J., Shively, Kathryn M., Sommers, Olivia, Anderson, Kailyn, Regnier, Michael, Bamshad, Michael J.
Published in HGG advances (13.07.2023)
Published in HGG advances (13.07.2023)
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