Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion
Jiang, Nian, Xie, Bowen, Xiao, Wenwu, Fan, Ming, Xu, Shanxiu, Duan, Yixin, Hamsafar, Yamah, Evans, Angela C., Huang, Jie, Zhou, Weibing, Lin, Xuelei, Ye, Ningrong, Wanggou, Siyi, Chen, Wen, Jing, Di, Fragoso, Ruben C., Dugger, Brittany N., Wilson, Paul F., Coleman, Matthew A., Xia, Shuli, Li, Xuejun, Sun, Lun-Quan, Monjazeb, Arta M., Wang, Aijun, Murphy, William J., Kung, Hsing-Jien, Lam, Kit S., Chen, Hong-Wu, Li, Jian Jian
Published in Nature communications (21.03.2022)
Published in Nature communications (21.03.2022)
Get full text
Journal Article
RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype
Cai, Demin, Wang, Junjian, Gao, Bei, Li, Jin, Wu, Feng, Zou, June X., Xu, Jianzhen, Jiang, Yuqian, Zou, Hongye, Huang, Zenghong, Borowsky, Alexander D., Bold, Richard J., Lara, Primo N., Li, Jian Jian, Chen, Xinbin, Lam, Kit S., To, Ka-Fai, Kung, Hsing-Jien, Fiehn, Oliver, Zhao, Ruqian, Evans, Ronald M., Chen, Hong-Wu
Published in Nature communications (11.10.2019)
Published in Nature communications (11.10.2019)
Get full text
Journal Article
A long noncoding RNA connects c-Myc to tumor metabolism
Hung, Chiu-Lien, Wang, Ling-Yu, Yu, Yen-Ling, Chen, Hong-Wu, Srivastava, Shiv, Petrovics, Gyorgy, Kung, Hsing-Jien
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2014)
Get full text
Journal Article
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Candas-Green, Demet, Xie, Bowen, Huang, Jie, Fan, Ming, Wang, Aijun, Menaa, Cheikh, Zhang, Yanhong, Zhang, Lu, Jing, Di, Azghadi, Soheila, Zhou, Weibing, Liu, Lin, Jiang, Nian, Li, Tao, Gao, Tianyi, Sweeney, Colleen, Shen, Rulong, Lin, Tzu-yin, Pan, Chong-xian, Ozpiskin, Omer M., Woloschak, Gayle, Grdina, David J., Vaughan, Andrew T., Wang, Ji Ming, Xia, Shuli, Monjazeb, Arta M., Murphy, William J., Sun, Lun-Quan, Chen, Hong-Wu, Lam, Kit S., Weichselbaum, Ralph R., Li, Jian Jian
Published in Nature communications (14.09.2020)
Published in Nature communications (14.09.2020)
Get full text
Journal Article
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer
Liu, Chengfei, Lou, Wei, Yang, Joy C., Liu, Liangren, Armstrong, Cameron M., Lombard, Alan P., Zhao, Ruining, Noel, Onika D. V., Tepper, Clifford G., Chen, Hong-Wu, Dall’Era, Marc, Evans, Christopher P., Gao, Allen C.
Published in Nature communications (16.11.2018)
Published in Nature communications (16.11.2018)
Get full text
Journal Article
KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC
Wang, Hung-Jung, Pochampalli, Mamata, Wang, Ling-Yu, Zou, June X, Li, Pei-Shan, Hsu, Sheng-Chieh, Wang, Bi-Juan, Huang, Shih-Han, Yang, Ping, Yang, Joy C., Chu, Cheng-Ying, Hsieh, Chia-Ling, Sung, Shian-Ying, Li, Chien-Feng, Tepper, Clifford G., Ann, David K., Gao, Allen C., Evans, Christopher P., Izumiya, Yoshihiro, Chuu, Chi-Pin, Wang, Wen-Ching, Chen, Hong-Wu, Kung, Hsing-Jien
Published in Oncogene (01.01.2019)
Published in Oncogene (01.01.2019)
Get full text
Journal Article
Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance
Zou, June X, Duan, Zhijian, Wang, Junjian, Sokolov, Alex, Xu, Jianzhen, Chen, Christopher Z, Li, Jian Jian, Chen, Hong-Wu
Published in Molecular cancer research (01.04.2014)
Published in Molecular cancer research (01.04.2014)
Get full text
Journal Article
CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer
Han, Shujun, Wei, Ryan, Zhang, Xiaodi, Jiang, Nian, Fan, Ming, Huang, Jie Hunter, Xie, Bowen, Zhang, Lu, Miao, Weili, Butler, Ashley Chen-Ping, Coleman, Matthew A, Vaughan, Andrew T, Wang, Yinsheng, Chen, Hong-Wu, Liu, Jiankang, Li, Jian Jian
Published in Frontiers in oncology (15.11.2019)
Published in Frontiers in oncology (15.11.2019)
Get full text
Journal Article
Androgen receptor blockade resistance with enzalutamide in prostate cancer results in immunosuppressive alterations in the tumor immune microenvironment
Xu, Pengfei, Yang, Joy C, Chen, Bo, Nip, Christopher, Van Dyke, Jonathan E, Zhang, Xiong, Chen, Hong-Wu, Evans, Christopher P, Murphy, William J, Liu, Chengfei
Published in Journal for immunotherapy of cancer (01.05.2023)
Published in Journal for immunotherapy of cancer (01.05.2023)
Get full text
Journal Article
Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling
Wang, Jun-Jian, Zou, June X., Wang, Hong, Duan, Zhi-Jian, Wang, Hai-Bin, Chen, Peng, Liu, Pei-Qing, Xu, Jian-Zhen, Chen, Hong-Wu
Published in Acta pharmacologica Sinica (01.08.2019)
Published in Acta pharmacologica Sinica (01.08.2019)
Get full text
Journal Article
Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer
Chen, Yixin, Tu, Mei-Juan, Han, Fangwei, Liu, Zhenzhen, Batra, Neelu, Lara, Primo N., Chen, Hong-Wu, Bi, Huichang, Yu, Ai-Ming
Published in Acta pharmaceutica Sinica. B (01.10.2023)
Published in Acta pharmaceutica Sinica. B (01.10.2023)
Get full text
Journal Article
KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis
Wang, Ling-Yu, Hung, Chiu-Lien, Chen, Yun-Ru, Yang, Joy C., Wang, Junjian, Campbell, Mel, Izumiya, Yoshihiro, Chen, Hong-Wu, Wang, Wen-Ching, Ann, David K., Kung, Hsing-Jien
Published in Cell reports (Cambridge) (13.09.2016)
Published in Cell reports (Cambridge) (13.09.2016)
Get full text
Journal Article
KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation
Hsia, Datsun A., Tepper, Clifford G., Pochampalli, Mamata R., Hsia, Elaine Y. C., Izumiya, Chie, Huerta, Steve B., Wright, Michael E., Chen, Hong-Wu, Kung, Hsing-Jien, Izumiya, Yoshihiro, Wang, James C.
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2010)
Get full text
Journal Article
Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling
Zhang, Xiong, Huang, Zenghong, Wang, Junjian, Ma, Zhao, Yang, Joy, Corey, Eva, Evans, Christopher P, Yu, Ai-Ming, Chen, Hong-Wu
Published in Cancers (01.04.2021)
Published in Cancers (01.04.2021)
Get full text
Journal Article