Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility
Byers, Spencer, Buchler, Ingrid P., DePasquale, Michael, Rowley, Helen L., Kulkarni, Rajiv S., Pinder, Lucy, Kolobova, Anna, Li, Cailian, Au, Vinh, Akuma, Daniel, Zhang, Gongliang, Wei, Huijun, Cheetham, Sharon C., Barrow, James C., Carr, Gregory V.
Published in Psychopharmacology (01.09.2020)
Published in Psychopharmacology (01.09.2020)
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Journal Article
The utility of animal models to evaluate novel anti‐obesity agents
Vickers, Steven P, Jackson, Helen C, Cheetham, Sharon C
Published in British journal of pharmacology (01.10.2011)
Published in British journal of pharmacology (01.10.2011)
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Journal Article
Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model
Fromont, Christophe, Atzori, Alessio, Kaur, Divneet, Hashmi, Lubna, Greco, Graziella, Cabanillas, Alejandro, Nguyen, Huy Van, Jones, D. Heulyn, Garzón, Miguel, Varela, Ana, Stevenson, Brett, Iacobini, Greg P, Lenoir, Marc, Rajesh, Sundaresan, Box, Clare, Kumar, Jitendra, Grant, Paige, Novitskaya, Vera, Morgan, Juliet, Sorrell, Fiona J, Redondo, Clara, Kramer, Andreas, Harris, C. John, Leighton, Brendan, Vickers, Steven P, Cheetham, Sharon C, Kenyon, Colin, Grabowska, Anna M, Overduin, Michael, Berditchevski, Fedor, Weston, Chris J, Knapp, Stefan, Fischer, Peter M, Butterworth, Sam
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
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Journal Article
Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet
Vickers, Steven P, Cheetham, Sharon C, Headland, Katie R, Dickinson, Keith, Grempler, Rolf, Mayoux, Eric, Mark, Michael, Klein, Thomas
Published in Diabetes, metabolic syndrome and obesity (01.01.2014)
Published in Diabetes, metabolic syndrome and obesity (01.01.2014)
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Journal Article
Receptor Occupancy and Brain Free Fraction
WATSON, Jeanette, WRIGHT, Sara, LUCAS, Adam, CLARKE, Kirsten L, VIGGERS, Jean, CHEETHAM, Sharon, JEFFREY, Phil, PORTER, Rod, READ, Kevin D
Published in Drug metabolism and disposition (01.04.2009)
Published in Drug metabolism and disposition (01.04.2009)
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Journal Article
Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments
Chapman, Victoria, Vickers, Steven, Cheetham, Sharon, Byrne, Frederika Maria
Published in Journal of Diabetes Research (01.01.2015)
Published in Journal of Diabetes Research (01.01.2015)
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Journal Article
Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats
Jones, Robert B., Vickers, Steven P., Cheetham, Sharon C., Headland, Katie R., Mark, Michael, Klein, Thomas
Published in European journal of pharmacology (15.04.2014)
Published in European journal of pharmacology (15.04.2014)
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Journal Article
Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats
Izzi-Engbeaya, Chioma, Ma, Yue, Buckley, Niki W., Ratnasabapathy, Risheka, Richardson, Errol, Counsell, John R., Fernandes-Freitas, Isabel, Norton, Mariana, Farooq, Gala, Mirza, Zainab, Cai, Mingzhu, Cheetham, Sharon, Seckl, Jonathan, Murphy, Kevin, Dhillo, Waljit S., Gardiner, James
Published in Molecular metabolism (Germany) (01.06.2020)
Published in Molecular metabolism (Germany) (01.06.2020)
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Journal Article
Prokineticin 2 Is a Hypothalamic Neuropeptide That Potently Inhibits Food Intake
GARDINER, James V, BATAVELJIC, Attia, EBLING, Francis J. P, VICKERS, Steven P, CHEETHAM, Sharon, GHATEI, Mohammad A, BLOOM, Stephen R, DHILLO, Waljit S, PATEL, Neekhil A, BEWICK, Gavin A, ROY, Debabrata, CAMPBELL, Daniel, GREENWOOD, Hannah C, MURPHY, Kevin G, HAMEED, Saira, JETHWA, Preeti H
Published in Diabetes (New York, N.Y.) (01.02.2010)
Published in Diabetes (New York, N.Y.) (01.02.2010)
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Journal Article
Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals
Vickers, Steven P, Cheetham, Sharon C, Birmingham, Gareth D, Rowley, Helen L, Headland, Katie R, Dickinson, Keith, Grempler, Rolf, Hocher, Berthold, Mark, Michael, Klein, Thomas
Published in Clinical laboratory (Heidelberg) (01.01.2012)
Published in Clinical laboratory (Heidelberg) (01.01.2012)
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Dopamine, but Not Norepinephrine or Serotonin, Reuptake Inhibition Reverses Motor Deficits in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Primates
Hansard, Matthew J, Smith, Lance A, Jackson, Michael J, Cheetham, Sharon C, Jenner, Peter
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
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Journal Article
Metabolic consequences of antipsychotic therapy: preclinical and clinical perspectives on diabetes, diabetic ketoacidosis, and obesity
Heal, David J, Gosden, Jane, Jackson, Helen C, Cheetham, Sharon C, Smith, Sharon L
Published in Handbook of experimental pharmacology (01.01.2012)
Published in Handbook of experimental pharmacology (01.01.2012)
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Journal Article
Dexamethasone and Enalaprilat but Not SB525334 Exhibit Anti-Inflammatory Properties in Precision-Cut Kidney Slices (PCKSs) Obtained from Mice with Adriamycin-Induced Nephropathy: SA-PO285
Pijacka, Wioletta, Lincevicius, Gisele, Willis, Jessica, Levers, Connor T., Butler, Stephanie, Vickers, Steven, Cheetham, Sharon
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates
Hansard, Matthew J., Smith, Lance A., Jackson, Michael J., Cheetham, Sharon C., Jenner, Peter
Published in Movement disorders (01.01.2004)
Published in Movement disorders (01.01.2004)
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Journal Article
Reduced dopamine turnover in the basal ganglia of depressed suicides
Bowden, Christine, Cheetham, Sharon C, Lowther, Sandra, Katona, Cornelius L.E, Crompton, M.Rufus, Horton, Roger W
Published in Brain research (19.09.1997)
Published in Brain research (19.09.1997)
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